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Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

Machine Learning · Computer Science 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…

Positron Emission Tomography (PET) is an important tool for studying Alzheimer's disease (AD). PET scans can be used as diagnostics tools, and to provide molecular characterization of patients with cognitive disorders. However, multiple…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Bo Zhou , Rui Wang , Ming-Kai Chen , Adam P. Mecca , Ryan S. O'Dell , Christopher H. Van Dyck , Richard E. Carson , James S. Duncan , Chi Liu

In recent days, Convolutional Neural Networks (CNN) have demonstrated impressive performance in medical image analysis. However, there is a lack of clear understanding of why and how the Convolutional Neural Network performs so well for…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Jyoti Islam , Yanqing Zhang

Computed tomography perfusion (CTP) and magnetic resonance perfusion (MRP) are widely used in acute ischemic stroke assessment and other cerebrovascular conditions to generate quantitative maps of cerebral hemodynamics. While commercial…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Marijn Borghouts , Ruisheng Su

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Fusing multi-modality medical images, such as MR and PET, can provide various anatomical or functional information about human body. But PET data is always unavailable due to different reasons such as cost, radiation, or other limitations.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Shengye Hu , Baiying Lei , Yong Wang , Zhiguang Feng , Yanyan Shen , Shuqiang Wang

Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…

Medical Physics · Physics 2018-08-01 Kuang Gong , Jaewon Yang , Kyungsang Kim , Georges El Fakhri , Youngho Seo , Quanzheng Li

Background: Alzheimer's disease (AD) diagnosis heavily relies on amyloid-beta positron emission tomography (Abeta-PET), which is limited by high cost and limited accessibility. This study explores whether Abeta-PET spatial patterns can be…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhengjie Zhang , Xiaoxie Mao , Qihao Guo , Shaoting Zhang , Qi Huang , Mu Zhou , Fang Xie , Mianxin Liu

Accurate dose calculations in proton therapy rely on high-quality CT images. While planning CTs (pCTs) serve as a reference for dosimetric planning, Cone Beam CT (CBCT) is used throughout Adaptive Radiotherapy (ART) to generate sCTs for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 David Vallmanya Poch , Yorick Estievenart , Elnura Zhalieva , Sukanya Patra , Mohammad Yaqub , Souhaib Ben Taieb

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Transcranial MRI-guided focused ultrasound (TcMRgFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively under MRI guidance. It is clinically approved to thermally ablate regions of the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Charles F. Caskey , Benoit M. Dawant

Positron emission tomographs (PET) do not measure an image directly. Instead, they measure at the boundary of the field-of-view (FOV) of PET tomograph a sinogram that consists of measurements of the sums of all the counts along the lines…

Optical flow estimation aims to find the 2D motion field by identifying corresponding pixels between two images. Despite the tremendous progress of deep learning-based optical flow methods, it remains a challenge to accurately estimate…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Xiuchao Sui , Shaohua Li , Xue Geng , Yan Wu , Xinxing Xu , Yong Liu , Rick Goh , Hongyuan Zhu

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Early detection of COVID-19 is vital to control its spread. Deep learning methods have been presented to detect suggestive signs of COVID-19 from chest CT images. However, due to the novelty of the disease, annotated volumetric data are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Azael M. Sousa , Fabiano Reis , Rachel Zerbini , João L. D. Comba , Alexandre X. Falcão

Objective: The paper focuses on development of robust and accurate processing solutions for continuous and cuff-less blood pressure (BP) monitoring. In this regard, a robust deep learning-based framework is proposed for computation of low…

Machine Learning · Computer Science 2022-01-03 Soheil Zabihi , Elahe Rahimian , Fatemeh Marefat , Amir Asif , Pedram Mohseni , Arash Mohammadi

Purpose: To perform and evaluate water-fat signal separation of whole-body gradient echo scans using convolutional neural networks. Methods: Whole-body gradient echo scans of 240 subjects, each consisting of 5 bipolar echoes, were used.…

Computer Vision and Pattern Recognition · Computer Science 2019-05-01 Jonathan Andersson , Håkan Ahlström , Joel Kullberg

It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…