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Tens of thousands of simultaneous hypothesis tests are routinely performed in genomic studies to identify differentially expressed genes. However, due to unmeasured confounders, many standard statistical approaches may be substantially…

Methodology · Statistics 2025-03-18 Jin-Hong Du , Larry Wasserman , Kathryn Roeder

We study high-dimensional distribution learning in an agnostic setting where an adversary is allowed to arbitrarily corrupt an $\varepsilon$-fraction of the samples. Such questions have a rich history spanning statistics, machine learning…

Data Structures and Algorithms · Computer Science 2019-03-18 Ilias Diakonikolas , Gautam Kamath , Daniel Kane , Jerry Li , Ankur Moitra , Alistair Stewart

Hypothesis tests in models whose dimension far exceeds the sample size can be formulated much like the classical studentized tests only after the initial bias of estimation is removed successfully. The theory of debiased estimators can be…

Machine Learning · Statistics 2017-02-22 Jelena Bradic , Mladen Kolar

While robust divergence such as density power divergence and $\gamma$-divergence is helpful for robust statistical inference in the presence of outliers, the tuning parameter that controls the degree of robustness is chosen in a…

Methodology · Statistics 2021-09-15 Shonosuke Sugasawa , Shouto Yonekura

For large-scale testing with graph-associated data, we present an empirical Bayes mixture technique to score local false discovery rates. Compared to empirical Bayes procedures that ignore the graph, the proposed method gains power in…

Methodology · Statistics 2019-11-26 TIen Vo , Vamsi Ithapu , Vikas Singh , Michael A. Newton

Statistical inference for high-dimensional regression heteroskedasticity is an important but under-explored problem. The current paper aims at filling this gap by proposing two tests, namely the variance difference test and the variance…

Methodology · Statistics 2022-12-06 Chi Chien-Ming

In this paper, we study inference for high-dimensional data characterized by small sample sizes relative to the dimension of the data. In particular, we provide an infinite-dimensional framework to study statistical models that involve…

Statistics Theory · Mathematics 2010-02-25 Jim Kuelbs , Anand N. Vidyashankar

In our paper, we focus on robust variable selection for missing data and measurement error. Missing data and measurement errors can lead to confusing data distribution. We propose an exponential loss function with a tuning parameter to…

Methodology · Statistics 2025-07-01 Zhenhao Zhang , Yunquan Song

This paper proposes an overidentifying restriction test for high-dimensional linear instrumental variable models. The novelty of the proposed test is that it allows the number of covariates and instruments to be larger than the sample size.…

Econometrics · Economics 2024-05-08 Qingliang Fan , Zijian Guo , Ziwei Mei

This paper proposes a decorrelation-based approach to test hypotheses and construct confidence intervals for the low dimensional component of high dimensional proportional hazards models. Motivated by the geometric projection principle, we…

Machine Learning · Statistics 2014-12-17 Ethan X. Fang , Yang Ning , Han Liu

Many economic and causal parameters depend on nonparametric or high dimensional first steps. We give a general construction of locally robust/orthogonal moment functions for GMM, where moment conditions have zero derivative with respect to…

Although the standard formulations of prediction problems involve fully-observed and noiseless data drawn in an i.i.d. manner, many applications involve noisy and/or missing data, possibly involving dependence, as well. We study these…

Statistics Theory · Mathematics 2015-03-19 Po-Ling Loh , Martin J. Wainwright

We consider multiple testing with false discovery rate (FDR) control when p-values have discrete and heterogeneous null distributions. We propose a new estimator of the proportion of true null hypotheses and demonstrate that it is less…

Methodology · Statistics 2018-03-15 Xiongzhi Chen , Rebecca W. Doerge , Joseph F. Heyse

We are interested in the problem of robust parametric estimation of a density from $n$ i.i.d. observations. By using a practice-oriented procedure based on robust tests, we build an estimator for which we establish non-asymptotic risk…

Statistics Theory · Mathematics 2016-03-31 Mathieu Sart

Bayesian inference is a widely used technique for real-time characterization of quantum systems. It excels in experimental characterization in the low data regime, and when the measurements have degrees of freedom. A decisive factor for its…

Quantum Physics · Physics 2025-07-10 Alexandra Ramôa , Raffaele Santagati , Nathan Wiebe

We propose a new inferential framework for constructing confidence regions and testing hypotheses in statistical models specified by a system of high dimensional estimating equations. We construct an influence function by projecting the…

Statistics Theory · Mathematics 2016-06-24 Matey Neykov , Yang Ning , Jun S. Liu , Han Liu

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

In this paper we investigate the question of estimating the Gram operator by a robust estimator from an i.i.d. sample in a separable Hilbert space and we present uniform bounds that hold under weak moment assumptions. The approach consists…

Statistics Theory · Mathematics 2017-04-03 Ilaria Giulini

The use of M-estimators in generalized linear regression models in high dimensional settings requires risk minimization with hard $L_0$ constraints. Of the known methods, the class of projected gradient descent (also known as iterative hard…

Machine Learning · Computer Science 2014-10-22 Prateek Jain , Ambuj Tewari , Purushottam Kar

Modern heterogeneity-robust difference-in-differences estimators derive their asymptotic properties under iid, cluster, or fixed-design frameworks that abstract from complex survey sampling, yet practitioners routinely apply them to…

Methodology · Statistics 2026-05-12 Isaac Gerber