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The adoption of Digital Twin technologies is rapidly expanding in diverse industrial, economic, and societal domains. Over the past decade, a multitude of studies, surveys, and investigations have been conducted, examining the nature,…

Software Engineering · Computer Science 2026-03-09 Philipp Zech , Yanis Mair , Michael Vierhauser , Pablo Oliveira Antonino , Frank Schnicke , Tony Clark

The real-time supervision of production processes is a common challenge across several industries. It targets process component monitoring and its predictive maintenance in order to ensure safety, uninterrupted production and maintain high…

Machine Learning · Computer Science 2026-02-27 Osimone Imhogiemhe , Yoann Jus , Hubert Lejeune , Saïd Moussaoui

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

Artificial Intelligence · Computer Science 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

As the real-time digital counterpart of a physical system or process, digital twins are utilized for system simulation and optimization. Neural networks are one way to build a digital twins model by using data especially when a…

Machine Learning · Computer Science 2021-12-03 Chao Sun , Victor Guang Shi

Digital twins offer a powerful framework for subject-specific simulation and clinical decision support, yet their development often hinges on accurate, individualized anatomical modeling. In this work, we present a rule-based approach for…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Robert Graf , Tanja Lerchl , Kati Nispel , Hendrik Möller , Matan Atad , Julian McGinnis , Julius Maria Watrinet , Johannes Paetzold , Daniel Rueckert , Jan S. Kirschke

Although transformer is preferred in natural language processing, some studies has only been applied to the field of medical imaging in recent years. For its long-term dependency, the transformer is expected to contribute to unconventional…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Jing Xu

Digital Twins hold great potential to personalize clinical patient care, provided the concept is translated to meet specific requirements emerging from established clinical workflows. We present a general and unspecialized Digital Twin…

Digital Twin (DT) technology revolutionizes industrial processes by enabling the representation of physical entities and their dynamics to enhance productivity and operational efficiency. It has emerged as a vital enabling technology in the…

Networking and Internet Architecture · Computer Science 2026-02-02 Eduardo Freitas , Assis T. de Oliveira Filho , Pedro R. X. do Carmo , Djamel Sadok , Judith Kelner

The proliferation of electronic devices has greatly transformed every aspect of human life, such as communication, healthcare, transportation, and energy. Unfortunately, the global electronics supply chain is vulnerable to various attacks,…

Cryptography and Security · Computer Science 2025-09-15 Blessing Airehenbuwa , Touseef Hasan , Souvika Sarkar , Ujjwal Guin

A digital twin contains up-to-date data-driven models of the physical world being studied and can use simulation to optimise the physical world. However, the analysis made by the digital twin is valid and reliable only when the model is…

Artificial Intelligence · Computer Science 2024-11-01 Nan Zhang , Rami Bahsoon , Nikos Tziritas , Georgios Theodoropoulos

This paper aims to provide a comprehensive critical overview on how entities and their interactions in Complex Networked Systems (CNS) are modelled across disciplines as they approach their ultimate goal of creating a Digital Twin (DT) that…

Systems and Control · Electrical Eng. & Systems 2022-02-22 Jiaqi Wen , Bogdan Gabrys , Katarzyna Musial

A framework for creating and updating digital twins for dynamical systems from a library of physics-based functions is proposed. The sparse Bayesian machine learning is used to update and derive an interpretable expression for the digital…

Machine Learning · Statistics 2022-12-20 Tapas Tripura , Aarya Sheetal Desai , Sondipon Adhikari , Souvik Chakraborty

Digital twins are virtual replicas of physical entities and are poised to transform personalized medicine through the real-time simulation and prediction of human physiology. Translating this paradigm from engineering to biomedicine…

We present methods and applications for the development of digital twins (DT) for urban traffic management. While the majority of studies on the DT focus on its ``eyes," which is the emerging sensing and perception like object detection and…

Systems and Control · Electrical Eng. & Systems 2026-02-05 Yongjie Fu , Mehmet K. Turkcan , Mahshid Ghasemi , Zhaobin Mo , Chengbo Zang , Abhishek Adhikari , Zoran Kostic , Gil Zussman , Xuan Di

Supercomputers are complex, dynamic systems that serve thousands of users and are built with thousands of compute nodes. Due to the vast amounts of system and performance data needed to accurately capture their status, supercomputers…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-31 Elena Baskakova , William Bergeron , Matthew Hubbell , Hayden Jananthan , Jeremy Kepner

The design and operation of systems are conventionally viewed as a sequential decision-making process that is informed by data from physical experiments and simulations. However, the integration of these high-dimensional and heterogeneous…

Applications · Statistics 2025-03-04 Anton van Beek , Vispi Karkaria , Wei Chen

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

The Digital Twins (DT) has quickly become a hot topic since it was proposed. It not only appears in all kinds of commercial propaganda, but also is widely quoted by academic circles. However, there are misstatements and misuse of the term…

Computational Engineering, Finance, and Science · Computer Science 2022-03-25 Jiehan Zhou , Shouhua Zhang , Mu Gu

A Mobility Digital Twin is an emerging implementation of digital twin technology in the transportation domain, which creates digital replicas for various physical mobility entities, such as vehicles, drivers, and pedestrians. Although a few…

Networking and Internet Architecture · Computer Science 2023-07-20 Yueyang Liu , Xiaolong Tu , Dawei Chen , Kyungtae Han , Onur Altintas , Haoxin Wang , Jiang Xie
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