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Real-world data typically contain a large number of features that are often heterogeneous in nature, relevance, and also units of measure. When assessing the similarity between data points, one can build various distance measures using…

Machine Learning · Statistics 2022-05-27 Aldo Glielmo , Claudio Zeni , Bingqing Cheng , Gabor Csanyi , Alessandro Laio

It is well known that there is no direct one-to-one relation between $p$-values and likelihood ratios or Bayes factors, since their relation crucially involves the sample size $n$. We investigate their (asymptotic) relation in a…

Statistics Theory · Mathematics 2026-03-23 Wouter Kager , Ronald Meester

There exists no consensus on the meaning of the term "randomization test". Contradicting uses of the term are leading to confusion, misunderstandings and indeed invalid data analyses. As we point out, a main source of the confusion is that…

Methodology · Statistics 2024-03-25 Jesse Hemerik

We describe a modified sequential probability ratio test that can be used to reduce the average sample size required to perform statistical hypothesis tests at specified levels of significance and power. Examples are provided for $z$ tests,…

Methodology · Statistics 2020-12-04 Sandipan Pramanik , Valen E. Johnson , Anirban Bhattacharya

Valid empirical studies build confidence in scientific findings. Fortunately, it is now common for software engineering researchers to consider threats to validity when designing their studies and to discuss them as part of their…

Software Engineering · Computer Science 2024-02-14 Marvin Wyrich , Sven Apel

As increasingly complex hypothesis-testing scenarios are considered in many scientific fields, analytic derivation of null distributions is often out of reach. To the rescue comes Monte Carlo testing, which may appear deceptively simple: as…

Methodology · Statistics 2015-04-13 Egil Ferkingstad , Lars Holden , Geir Kjetil Sandve

Two-sided statistical tests and p-values are well defined only when the test statistic in question has a symmetric distribution. A new two-sided p-value called conditional p-value $P_C$ is introduced here. It is closely related to the…

Statistics Theory · Mathematics 2008-10-14 Elena Kulinskaya

Small study effects occur when smaller studies show different, often larger, treatment effects than large ones, which may threaten the validity of systematic reviews and meta-analyses. The most well-known reasons for small study effects…

Positive predictive value and negative predictive value are two widely used parameters to assess the clinical usefulness of a medical diagnostic test. When there are two diagnostic tests, it is recommendable to make a comparative assessment…

Methodology · Statistics 2024-05-29 Antonio Martín Andrés , Pedro Femia Marzo

The study of associations and their causal explanations is a central research activity whose methodology varies tremendously across fields. Even within specialized subfields, comparisons across textbooks and journals reveals that the basics…

Methodology · Statistics 2025-10-13 Sander Greenland

Statistical hypothesis testing, as formalized by 20th Century statisticians and taught in college statistics courses, has been a cornerstone of 100 years of scientific progress. Nevertheless, the methodology is increasingly questioned in…

Methodology · Statistics 2024-08-22 Brian Dennis , Mark L Taper , José M Ponciano

Recent discussions on alternative facts, fake news, and post truth politics have motivated research on creating technologies that allow people not only to access information, but also to assess the credibility of the information presented…

Information Retrieval · Computer Science 2017-08-25 Christina Lioma , Jakob Grue Simonsen , Birger Larsen

We introduce probability estimation, a broadly applicable framework to certify randomness in a finite sequence of measurement results without assuming that these results are independent and identically distributed. Probability estimation…

Quantum Physics · Physics 2018-11-30 Yanbao Zhang , Emanuel Knill , Peter Bierhorst

Randomness is a central concept to statistics and physics. Here, a statistical analysis shows experimental evidence that tossing coins and finding last digits of prime numbers are identical regarding statistics for equally likely outcomes.…

Applications · Statistics 2019-10-29 Yeseul Kim , Byung Mook Weon

Statistics is sometimes described as the science of reasoning under uncertainty. Statistical models provide one view of this uncertainty, but what is frequently neglected is the 'invisible' portion of uncertainty: that assumed not to exist…

Methodology · Statistics 2026-03-18 Oliver L. Pescott , Robin J. Boyd , Gary D. Powney , Gavin B. Stewart

An exciting recent development is the uptake of deep neural networks in many scientific fields, where the main objective is outcome prediction with the black-box nature. Significance testing is promising to address the black-box issue and…

Machine Learning · Statistics 2022-06-22 Ben Dai , Xiaotong Shen , Wei Pan

Randomization tests deliver exact finite-sample Type 1 error control when the null satisfies the randomization hypothesis. In practice, achieving these guarantees often requires stronger conditions than the null hypothesis of primary…

Econometrics · Economics 2026-04-03 Deniz Dutz , Xinyi Zhang

I have three goals in this article: (1) To show the enormous potential of bootstrapping and permutation tests to help students understand statistical concepts including sampling distributions, standard errors, bias, confidence intervals,…

Other Statistics · Statistics 2014-11-20 Tim Hesterberg

The present discussion concerning certain fundamental physical theories (such as string theory and multiverse cosmology) has reopened the demarcation problem between science and non-science. While parts of the physics community see the…

History and Philosophy of Physics · Physics 2017-02-23 Helge Kragh

How should we evaluate the effect of a policy on the likelihood of an undesirable event, such as conflict? The significance test has three limitations. First, relying on statistical significance misses the fact that uncertainty is a…

Methodology · Statistics 2022-05-03 Akisato Suzuki