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This project aims to break down large pathology images into small tiles and then cluster those tiles into distinct groups without the knowledge of true labels, our analysis shows how difficult certain aspects of clustering tumorous and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Mostafa Ibrahim , Kevin Bryson

Segmentation of objects of interest is one of the central tasks in medical image analysis, which is indispensable for quantitative analysis. When developing machine-learning based methods for automated segmentation, manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Hang Li , Dong Wei , Shilei Cao , Kai Ma , Liansheng Wang , Yefeng Zheng

Recent advances in deep learning have greatly facilitated the automated segmentation of ultrasound images, which is essential for nodule morphological analysis. Nevertheless, most existing methods depend on extensive and precise annotations…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Xingyue Zhao , Zhongyu Li , Xiangde Luo , Peiqi Li , Peng Huang , Jianwei Zhu , Yang Liu , Jihua Zhu , Meng Yang , Shi Chang , Jun Dong

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

Electronic health records capture patient information using structured controlled vocabularies and unstructured narrative text. While structured data typically encodes lab values, encounters and medication lists, unstructured data captures…

Computers and Society · Computer Science 2015-02-17 Preethi Raghavan , James L. Chen , Eric Fosler-Lussier , Albert M. Lai

Various deep learning algorithms have been developed to analyze different types of clinical data including clinical text classification and extracting information from 'free text' and so on. However, automate the keyword extraction from the…

Computation and Language · Computer Science 2019-10-25 Matthew Tang , Priyanka Gandhi , Md Ahsanul Kabir , Christopher Zou , Jordyn Blakey , Xiao Luo

In this paper we present a method for the unsupervised clustering of high-dimensional binary data, with a special focus on electronic healthcare records. We present a robust and efficient heuristic to face this problem using tensor…

Machine Learning · Statistics 2017-08-31 Matteo Ruffini , Ricard Gavaldà , Esther Limón

Often in medical imaging, it is prohibitively challenging to produce enough boundary annotations to train deep neural networks for accurate tumor segmentation. We propose the use of weak labels about whether an image presents tumor or…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Eugene Vorontsov , Pavlo Molchanov , Christopher Beckham , Jan Kautz , Samuel Kadoury

Clinical Practice Guidelines (CPGs) for cancer diseases evolve rapidly due to new evidence generated by active research. Currently, CPGs are primarily published in a document format that is ill-suited for managing this developing knowledge.…

Artificial Intelligence · Computer Science 2023-07-21 Pralaypati Ta , Bhumika Gupta , Arihant Jain , Sneha Sree C , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

There is a keen interest in characterizing variation in the microbiome across cancer patients, given increasing evidence of its important role in determining treatment outcomes. Here our goal is to discover subgroups of patients with…

Applications · Statistics 2022-12-06 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert Jenq , Christine Peterson

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

Information extraction from narrative clinical notes is useful for patient care, as well as for secondary use of medical data, for research or clinical purposes. Many studies focused on information extraction from English clinical texts,…

Computation and Language · Computer Science 2021-04-05 Emma Chiaramello , Francesco Pinciroli , Alberico Bonalumi , Angelo Caroli , Gabriella Tognola

In this work, we consider the exponentially growing subarea of genetics in cancer. The need to synthesize and centralize this evidence for dissemination has motivated a team of physicians to manually construct and maintain a knowledge base…

Computation and Language · Computer Science 2020-05-27 Somin Wadhwa , Kanhua Yin , Kevin S. Hughes , Byron C. Wallace

We introduce a graph-theoretic approach to extract clusters and hierarchies in complex data-sets in an unsupervised and deterministic manner, without the use of any prior information. This is achieved by building topologically embedded…

Data Analysis, Statistics and Probability · Physics 2014-02-13 Won-Min Song , T. Di Matteo , Tomaso Aste

The data-intensive nature of supervised classification drives the interest of the researchers towards unsupervised approaches, especially for problems such as medical image segmentation, where labeled data is scarce. Building on the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

Clinical notes are an efficient way to record patient information but are notoriously hard to decipher for non-experts. Automatically simplifying medical text can empower patients with valuable information about their health, while saving…

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Training deep neural networks usually requires a large amount of labeled data to obtain good performance. However, in medical image analysis, obtaining high-quality labels for the data is laborious and expensive, as accurately annotating…

Computer Vision and Pattern Recognition · Computer Science 2020-05-20 Quande Liu , Lequan Yu , Luyang Luo , Qi Dou , Pheng Ann Heng