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Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…

Clinical Text Notes (CTNs) contain physicians' reasoning process, written in an unstructured free text format, as they examine and interview patients. In recent years, several studies have been published that provide evidence for the…

Computation and Language · Computer Science 2022-08-19 Hlynur D. Hlynsson , Steindór Ellertsson , Jón F. Daðason , Emil L. Sigurdsson , Hrafn Loftsson

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

In recent years, the research landscape of machine learning in medical imaging has changed drastically from supervised to semi-, weakly- or unsupervised methods. This is mainly due to the fact that ground-truth labels are time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Turkay Kart , Wenjia Bai , Ben Glocker , Daniel Rueckert

A large fraction of the electronic health records consists of clinical measurements collected over time, such as blood tests, which provide important information about the health status of a patient. These sequences of clinical measurements…

The extraction of relevant data from Electronic Health Records (EHRs) is crucial to identifying symptoms and automating epidemiological surveillance processes. By harnessing the vast amount of unstructured text in EHRs, we can detect…

Computation and Language · Computer Science 2025-02-10 Juliano Genari , Guilherme Tegoni Goedert

Extracting phenotypes from clinical text has been shown to be useful for a variety of clinical use cases such as identifying patients with rare diseases. However, reasoning with numerical values remains challenging for phenotyping in…

Computation and Language · Computer Science 2022-04-22 Ashwani Tanwar , Jingqing Zhang , Julia Ive , Vibhor Gupta , Yike Guo

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

Textual health records of cancer patients are usually protracted and highly unstructured, making it very time-consuming for health professionals to get a complete overview of the patient's therapeutic course. As such limitations can lead to…

Computation and Language · Computer Science 2023-08-08 Hugo Sousa , Arian Pasquali , Alípio Jorge , Catarina Sousa Santos , Mário Amorim Lopes

In the realm of precision medicine, effective patient stratification and disease subtyping demand innovative methodologies tailored for multi-omics data. Clustering techniques applied to multi-omics data have become instrumental in…

Machine Learning · Computer Science 2024-01-30 Bastian Pfeifer , Christel Sirocchi , Marcus D. Bloice , Markus Kreuzthaler , Martin Urschler

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Scalable and accurate identification of specific clinical outcomes has been enabled by machine-learning applied to electronic medical record (EMR) systems. The development of classification models requires the collection of a complete…

Methodology · Statistics 2020-11-09 W. Katherine Tan , Patrick J. Heagerty

This study investigates the use of unsupervised word embeddings and sequence features for sample representation in an active learning framework built to extract clinical concepts from clinical free text. The objective is to further reduce…

Computation and Language · Computer Science 2016-11-16 Mahnoosh Kholghi , Lance De Vine , Laurianne Sitbon , Guido Zuccon , Anthony Nguyen

Local clustering aims to identify specific substructures within a large graph without any additional structural information of the graph. These substructures are typically small compared to the overall graph, enabling the problem to be…

Machine Learning · Computer Science 2025-10-31 Zhaiming Shen , Sung Ha Kang

Automated summarization of clinical texts can reduce the burden of medical professionals. "Discharge summaries" are one promising application of the summarization, because they can be generated from daily inpatient records. Our preliminary…

Computation and Language · Computer Science 2022-12-21 Kenichiro Ando , Takashi Okumura , Mamoru Komachi , Hiromasa Horiguchi , Yuji Matsumoto

Unsupervised patient stratification is essential for disease subtype discovery, yet, despite growing evidence of molecular heterogeneity of non-oncological diseases, popular methods are benchmarked primarily using cancers with mutually…

Identifying patient diagnoses from discharge letters is essential to enable large-scale cohort selection and epidemiological research, but traditional supervised approaches rely on extensive manual annotation, which is often impractical for…

Computation and Language · Computer Science 2026-01-01 Vittorio Torri , Elisa Barbieri , Anna Cantarutti , Carlo Giaquinto , Francesca Ieva