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Data-driven dynamic models of cell biology can be used to predict cell response to unseen perturbations. Recent work (CellBox) had demonstrated the derivation of interpretable models with explicit interaction terms, in which the parameters…

Molecular Networks · Quantitative Biology 2021-04-15 Weiqi Ji , Bo Yuan , Ciyue Shen , Aviv Regev , Chris Sander , Sili Deng

This paper promotes the differential method as a new fruitful strategy for estimating a ground-state energy of a many-body system. The case of an arbitrary number of attractive Coulombian particles is specifically studied and we make some…

Nuclear Theory · Physics 2009-11-11 Amaury Mouchet

Familiarity with a simulation platform can seduce modellers into accepting untested assumptions for convenience of implementation. These assumptions may have consequences greater than commonly suspected, and it is important that modellers…

Quantitative Methods · Quantitative Biology 2014-02-28 Jerome K Vanclay

We present a data-driven machine-learning approach for modeling space-time socioeconomic dynamics. Through coarse-graining fine-scale observations, our modeling framework simplifies these complex systems to a set of tractable mechanistic…

Machine Learning · Computer Science 2024-07-26 James Koch , Pranab Roy Chowdhury , Heng Wan , Parin Bhaduri , Jim Yoon , Vivek Srikrishnan , W. Brent Daniel

Our simulation-based experiments are aimed to demonstrate a use case on the feasibility of fulfillment of global energy demand by primarily relying on solar energy through the integration of a longitudinally-distributed grid. These…

Computers and Society · Computer Science 2022-06-14 Harsh Vardhan , Neal M Sarkar , Himanshu Neema

Modeling geophysical processes as low-dimensional dynamical systems and regressing their vector field from data is a promising approach for learning emulators of such systems. We show that when the kernel of these emulators is also learned…

Atmospheric and Oceanic Physics · Physics 2021-08-11 Boumediene Hamzi , Romit Maulik , Houman Owhadi

We present a data-driven modeling strategy to overcome improperly modeled dynamics for systems exhibiting complex spatio-temporal behaviors. We propose a Deep Learning framework to resolve the differences between the true dynamics of the…

Machine Learning · Computer Science 2020-10-28 Maan Qraitem , Dhanushka Kularatne , Eric Forgoston , M. Ani Hsieh

Parameters of differential equations are essential to characterize intrinsic behaviors of dynamic systems. Numerous methods for estimating parameters in dynamic systems are computationally and/or statistically inadequate, especially for…

Methodology · Statistics 2026-01-27 Jianbin Tan , Guoyu Zhang , Xueqin Wang , Hui Huang , Fang Yao

This work explores the potential of using differentiable simulation for learning quadruped locomotion. Differentiable simulation promises fast convergence and stable training by computing low-variance first-order gradients using robot…

Robotics · Computer Science 2024-10-16 Yunlong Song , Sangbae Kim , Davide Scaramuzza

Complex systems in science and engineering sometimes exhibit behavior that changes across different regimes. Traditional global models struggle to capture the full range of this complex behavior, limiting their ability to accurately…

Machine Learning · Computer Science 2023-07-24 Okezzi F. Ukorigho , Opeoluwa Owoyele

The combination of high-dimensionality and disparity of time scales encountered in many problems in computational physics has motivated the development of coarse-grained (CG) models. In this paper, we advocate the paradigm of data-driven…

Computational Physics · Physics 2018-03-05 L. Felsberger , P. S. Koutsourelakis

Agricultural monitoring is critical for ensuring food security, maintaining sustainable farming practices, informing policies on mitigating food shortage, and managing greenhouse gas emissions. Traditional process-based physical models are…

Machine Learning · Computer Science 2025-05-14 Qi Cheng , Licheng Liu , Yao Zhang , Mu Hong , Shiyuan Luo , Zhenong Jin , Yiqun Xie , Xiaowei Jia

Building energy modeling is a key tool for optimizing the performance of building energy systems. Historically, a wide spectrum of methods has been explored -- ranging from conventional physics-based models to purely data-driven techniques.…

Systems and Control · Electrical Eng. & Systems 2025-07-24 Leandro Von Krannichfeldt , Kristina Orehounig , Olga Fink

Recent works exploring deep learning application to dynamical systems modeling have demonstrated that embedding physical priors into neural networks can yield more effective, physically-realistic, and data-efficient models. However, in the…

Neural and Evolutionary Computing · Computer Science 2020-11-30 Elliott Skomski , Jan Drgona , Aaron Tuor

Recent developments have created differentiable physics simulators designed for machine learning pipelines that can be accelerated on a GPU. While these can simulate biomechanical models, these opportunities have not been exploited for…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 R. James Cotton

Complex numerical weather prediction models incorporate a variety of physical processes, each described by multiple alternative physical schemes with specific parameters. The selection of the physical schemes and the choice of the…

Numerical Analysis · Computer Science 2018-02-23 Azam Moosavi , Vishwas Rao , Adrian Sandu

Substitution of well-grounded theoretical models by data-driven predictions is not as simple in engineering and sciences as it is in social and economic fields. Scientific problems suffer most times from paucity of data, while they may…

Machine Learning · Computer Science 2020-11-18 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Jose Antonio Sanz-Herrera , Manuel Doblaré

We present a Bayesian machine learning architecture that combines a physically motivated parametrization and an analytic error model for the likelihood with a deep generative model providing a powerful data-driven prior for complex signals.…

Instrumentation and Methods for Astrophysics · Physics 2019-12-10 Francois Lanusse , Peter Melchior , Fred Moolekamp

Evolution has resulted in highly developed abilities in many natural intelligences to quickly and accurately predict mechanical phenomena. Humans have successfully developed laws of physics to abstract and model such mechanical phenomena.…

Artificial Intelligence · Computer Science 2017-03-02 Sebastien Ehrhardt , Aron Monszpart , Niloy J. Mitra , Andrea Vedaldi

In numerical modeling of the Earth System, many processes remain unknown or ill represented (let us quote sub-grid processes, the dependence to unknown latent variables or the non-inclusion of complex dynamics in numerical models) but…

Data Analysis, Statistics and Probability · Physics 2019-03-19 Julien Brajard , Anastase Charantonis , Jérôme Sirven
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