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Mediation analysis for survival outcomes is challenging. Most existing methods quantify the treatment effect using the hazard ratio (HR) and attempt to decompose the HR into the direct effect of treatment plus an indirect, or mediated,…

Modern high-dimensional methods often adopt the "bet on sparsity" principle, while in supervised multivariate learning statisticians may face "dense" problems with a large number of nonzero coefficients. This paper proposes a novel…

Machine Learning · Statistics 2022-02-10 Yiyuan She , Jiahui Shen , Chao Zhang

In this work, we study the problem of clustering survival data $-$ a challenging and so far under-explored task. We introduce a novel semi-supervised probabilistic approach to cluster survival data by leveraging recent advances in…

Clustering has long been a popular unsupervised learning approach to identify groups of similar objects and discover patterns from unlabeled data in many applications. Yet, coming up with meaningful interpretations of the estimated clusters…

Methodology · Statistics 2020-05-26 Minjie Wang , Tianyi Yao , Genevera I. Allen

The premise of independence among subjects in the same cluster/group often fails in practice, and models that rely on such untenable assumption can produce misleading results. To overcome this severe deficiency, we introduce a new…

Methodology · Statistics 2022-02-22 Jussiane Nader Gonçalves , Wagner Barreto-Souza , Hernando Ombao

Clustering is considered a non-supervised learning setting, in which the goal is to partition a collection of data points into disjoint clusters. Often a bound $k$ on the number of clusters is given or assumed by the practitioner. Many…

Machine Learning · Computer Science 2012-02-01 Nir Ailon , Ron Begleiter

Most pseudo-label selection strategies in semi-supervised learning rely on fixed confidence thresholds, implicitly assuming that prediction confidence reliably indicates correctness. In practice, deep networks are often overconfident:…

Machine Learning · Computer Science 2026-02-27 Jinshi Liu , Pan Liu , Lei He

Causal inference analyses often use existing observational data, which in many cases has some clustering of individuals. In this paper we discuss propensity score weighting methods in a multilevel setting where within clusters individuals…

Applications · Statistics 2020-12-24 Youjin Lee , Trang Q. Nguyen , Elizabeth A. Stuart

In this paper we study the impact of exposure misclassification when cluster size is potentially informative (i.e., related to outcomes) and when misclassification is differential by cluster size. First, we show that misclassification in an…

Medical dialogue generation aims to provide automatic and accurate responses to assist physicians to obtain diagnosis and treatment suggestions in an efficient manner. In medical dialogues two key characteristics are relevant for response…

Computation and Language · Computer Science 2021-05-14 Dongdong Li , Zhaochun Ren , Pengjie Ren , Zhumin Chen , Miao Fan , Jun Ma , Maarten de Rijke

We present an excited-state-specific coupled-cluster approach in which both the molecular orbitals and cluster amplitudes are optimized for an individual excited state. The theory is formulated via a pseudoprojection of the traditional…

Chemical Physics · Physics 2023-11-27 Harrison Tuckman , Eric Neuscamman

Current Semi-supervised Learning (SSL) adopts the pseudo-labeling strategy and further filters pseudo-labels based on confidence thresholds. However, this mechanism has notable drawbacks: 1) setting the reasonable threshold is an open…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Jiaqi Wu , Junbiao Pang , Qingming Huang

When mapping subnational health and demographic indicators, direct weighted estimators of small area means based on household survey data can be unreliable when data are limited. If survey microdata are available, unit level models can…

Methodology · Statistics 2023-09-22 Peter A. Gao , Jon Wakefield

Assessment of multistate disease progression is commonplace in biomedical research, such as, in periodontal disease (PD). However, the presence of multistate current status endpoints, where only a single snapshot of each subject's…

Methodology · Statistics 2025-09-03 Snigdha Das , Minwoo Chae , Debdeep Pati , Dipankar Bandyopadhyay

Meta-analyses frequently include trials that report multiple effect sizes based on a common set of study participants. These effect sizes will generally be correlated. Cluster-robust variance-covariance estimators are a fruitful approach…

Methodology · Statistics 2022-03-07 Thilo Welz , Wolfgang Viechtbauer , Markus Pauly

In this paper, we propose a novel unsupervised clustering approach exploiting the hidden information that is indirectly introduced through a pseudo classification objective. Specifically, we randomly assign a pseudo parent-class label to…

Machine Learning · Computer Science 2018-02-12 Ozsel Kilinc , Ismail Uysal

Semi-supervised learning (SSL) methods, which can leverage a large amount of unlabeled data for improved performance, has attracted increasing attention recently. In this paper, we introduce a novel Context-aware Conditional Cross Pseudo…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Peng Liu , Guoyan Zheng

Selecting high-quality candidates from large datasets is critical in applications such as drug discovery, precision medicine, and alignment of large language models (LLMs). While Conformal Selection (CS) provides rigorous uncertainty…

Methodology · Statistics 2025-05-05 Tian Bai , Yue Zhao , Xiang Yu , Archer Y. Yang

Corrupted data sets containing noisy or missing observations are prevalent in various contemporary applications such as economics, finance and bioinformatics. Despite the recent methodological and algorithmic advances in high-dimensional…

Methodology · Statistics 2020-05-12 J. Wu , Z. Zheng , Y. Li , Y. Zhang

Estimation of treatment efficacy of real-world clinical interventions involves working with continuous outcomes such as time-to-death, re-hospitalization, or a composite event that may be subject to censoring. Counterfactual reasoning in…

Machine Learning · Computer Science 2022-08-11 Chirag Nagpal , Mononito Goswami , Keith Dufendach , Artur Dubrawski