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Related papers: Assessing Opportunities of SYCL for Biological Seq…

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Dynamic programming (DP) based algorithms are essential yet compute-intensive parts of numerous bioinformatics pipelines, which typically involve populating a 2-D scoring matrix based on a recursive formula, optionally followed by a…

Hardware Architecture · Computer Science 2024-11-07 Yingqi Cao , Anshu Gupta , Jason Liang , Yatish Turakhia

Lattice QCD calculations require significant computational effort, with the dominant fraction of resources typically spent in the numerical inversion of the Dirac operator. One of the simplest methods to solve such large and sparse linear…

High Energy Physics - Lattice · Physics 2021-12-01 Salvatore Cali , William Detmold , Grzegorz Korcyl , Piotr Korcyl , Phiala Shanahan

Similar to other programming models, compilers for SYCL, the open programming model for heterogeneous computing based on C++, would benefit from access to higher-level intermediate representations. The loss of high-level structure and…

Programming Languages · Computer Science 2023-12-21 Ettore Tiotto , Víctor Pérez , Whitney Tsang , Lukas Sommer , Julian Oppermann , Victor Lomüller , Mehdi Goli , James Brodman

The NVIDIA Collective Communication Library (NCCL) is a critical software layer enabling high-performance collectives on large-scale GPU clusters. Despite being open source with a documented API, its internal design remains largely opaque.…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-03 Zhiyi Hu , Siyuan Shen , Tommaso Bonato , Sylvain Jeaugey , Cedell Alexander , Eric Spada , James Dinan , Jeff Hammond , Torsten Hoefler

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Machine Learning · Computer Science 2024-11-28 Huifa Li , Jie Fu , Xinpeng Ling , Zhiyu Sun , Kuncan Wang , Zhili Chen

Batched linear solvers play a vital role in computational sciences, especially in the fields of plasma physics and combustion simulations. With the imminent deployment of the Aurora Supercomputer and other upcoming systems equipped with…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-28 Phuong Nguyen , Pratik Nayak , Hartwig Anzt

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

We present SPDL (Scalable and Performant Data Loading), an open-source, framework-agnostic library designed for efficiently loading array data to GPU. Data loading is often a bottleneck in AI applications, and is challenging to optimize…

We address the challenges associated with deploying neural networks on CPUs, with a particular focus on minimizing inference time while maintaining accuracy. Our novel approach is to use the dataflow (i.e., computation order) of a neural…

Hardware Architecture · Computer Science 2023-11-27 Cyrus Zhou , Zack Hassman , Ruize Xu , Dhirpal Shah , Vaugnn Richard , Yanjing Li

NVIDIA has been the main provider of GPU hardware in HPC systems for over a decade. Most applications that benefit from GPUs have thus been developed and optimized for the NVIDIA software stack. Recent exascale HPC systems are, however,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-12 Igor Sfiligoi , Emily A. Belli , Jeff Candy , Reuben D. Budiardja

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

Currently, the most energy-efficient hardware platforms for floating point-intensive calculations (also known as High Performance Computing, or HPC) are graphical processing units (GPUs). However, porting existing scientific codes to GPUs…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-28 Michele Martone , Julia Lawall

The pervasive adoption of Deep Learning (DL) and Graph Processing (GP) makes it a de facto requirement to build large-scale clusters of heterogeneous accelerators including GPUs and FPGAs. The OpenCL programming framework can be used on the…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-19 Yao Chen , Xin Long , Jiong He , Yuhang Chen , Hongshi Tan , Zhenxiang Zhang , Marianne Winslett , Deming Chen

Experience shows that on today's high performance systems the utilization of different acceleration cards in conjunction with a high utilization of all other parts of the system is difficult. Future architectures, like exascale clusters,…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-07 Patrick Diehl , Madhavan Seshadri , Thomas Heller , Hartmut Kaiser

In this proceedings we discuss the motivation, implementation details, and performance of a new physics code base called Grid. It is intended to be more performant, more general, but similar in spirit to QDP++\cite{QDP}. Our approach is to…

High Energy Physics - Lattice · Physics 2015-12-14 Peter Boyle , Azusa Yamaguchi , Guido Cossu , Antonin Portelli

COLA is a software library for lattice QCD, written in a combination of modern Fortran and C/C++. Intel and NVIDIA have dominated the HPC domain in the years leading up to the exascale era, but the status quo has changed with the arrival of…

High Energy Physics - Lattice · Physics 2023-02-03 Waseem Kamleh

While parallelism remains the main source of performance, architectural implementations and programming models change with each new hardware generation, often leading to costly application re-engineering. Most tools for performance…

Programming Languages · Computer Science 2022-07-04 William S. Moses , Ivan R. Ivanov , Jens Domke , Toshio Endo , Johannes Doerfert , Oleksandr Zinenko

We introduce OpenRAND, a C++17 library aimed at facilitating reproducible scientific research through the generation of statistically robust and yet replicable random numbers. OpenRAND accommodates single and multi-threaded applications on…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-01 Shihab Shahriar Khan , Bryce Palmer , Christopher Edelmaierd , Hasan Metin Aktulga

CUDA (formerly an abbreviation of Compute Unified Device Architecture) is a parallel computing platform and API model created by Nvidia allowing software developers to use a CUDA-enabled graphics processing unit (GPU) for general purpose…

Cryptography and Security · Computer Science 2021-09-14 Miroslav Dimitrov , Bernhard Esslinger
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