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Due to the wide applications of X-ray computed tomography (CT) in medical imaging activities, radiation exposure has become a major concern for public health. Sparse-view CT is a promising approach to reduce the radiation dose by…

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Sparse-view computed tomography (CT) reduces radiation exposure by subsampling projection views, but conventional reconstruction methods produce severe streak artifacts with undersampled data. While deep-learning-based methods enable…

Image and Video Processing · Electrical Eng. & Systems 2025-08-15 Jixiang Chen , Yiqun Lin , Yi Qin , Hualiang Wang , Xiaomeng Li

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

In this work, we introduce a new deep learning approach based on diffusion posterior sampling (DPS) to perform material decomposition from spectral CT measurements. This approach combines sophisticated prior knowledge from unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Xiao Jiang , Grace J. Gang , J. Webster Stayman

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Medical image acquisition is often intervented by unwanted noise that corrupts the information content. This paper introduces an unsupervised medical image denoising technique that learns noise characteristics from the available images and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Swati Rai , Jignesh S. Bhatt , S. K. Patra

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu

Objective: X-ray computed tomography employing sparse projection views has emerged as a contemporary technique to mitigate radiation dose. However, due to the inadequate number of projection views, an analytic reconstruction method…

Machine Learning · Computer Science 2025-01-10 Yoseob Han

Diffusion model shows remarkable potential on sparse-view computed tomography (SVCT) reconstruction. However, when a network is trained on a limited sample space, its generalization capability may be constrained, which degrades performance…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Zekun Zhou , Tan Liu , Bing Yu , Yanru Gong , Liu Shi , Qiegen Liu

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

We propose an effective denoising diffusion model for generating high-resolution images (e.g., 1024$\times$512), trained on small-size image patches (e.g., 64$\times$64). We name our algorithm Patch-DM, in which a new feature collage…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Zheng Ding , Mengqi Zhang , Jiajun Wu , Zhuowen Tu

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

X-ray Computed Tomography (CT) imaging has been widely used in clinical diagnosis, non-destructive examination, and public safety inspection. Sparse-view (sparse view) CT has great potential in radiation dose reduction and scan…

Medical Physics · Physics 2019-05-29 Kaichao Liang , Hongkai Yang , Yuxiang Xing

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Transformer has achieved great success in computer vision, while how to split patches in an image remains a problem. Existing methods usually use a fixed-size patch embedding which might destroy the semantics of objects. To address this…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Zhiyang Chen , Yousong Zhu , Chaoyang Zhao , Guosheng Hu , Wei Zeng , Jinqiao Wang , Ming Tang

Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Runyi Li

We propose a novel and unified method, measurement-conditioned denoising diffusion probabilistic model (MC-DDPM), for under-sampled medical image reconstruction based on DDPM. Different from previous works, MC-DDPM is defined in measurement…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Yutong Xie , Quanzheng Li

This letter introduces a dual application of denoising diffusion probabilistic model (DDPM)-based channel estimation algorithm integrating data denoising and augmentation. Denoising addresses the severe noise in raw signals at pilot…

Signal Processing · Electrical Eng. & Systems 2025-10-06 Yupeng Li , Ruhao Zhang , Yitong Liu , Chunju Shao , Jing Jin , Shijian Gao

Ultrasound images are widespread in medical diagnosis for musculoskeletal, cardiac, and obstetrical imaging due to the efficiency and non-invasiveness of the acquisition methodology. However, the acquired images are degraded by acoustic…

Image and Video Processing · Electrical Eng. & Systems 2023-06-14 Hojat Asgariandehkordi , Sobhan Goudarzi , Adrian Basarab , Hassan Rivaz