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Much of the focus in the area of knowledge distillation has been on distilling knowledge from a larger teacher network to a smaller student network. However, there has been little research on how the concept of distillation can be leveraged…

Neural and Evolutionary Computing · Computer Science 2019-01-29 Zhong Qiu Lin , Alexander Wong

Recent advances in fast sampling methods for diffusion models have demonstrated significant potential to accelerate generation on image modalities. We apply these methods to 3-dimensional molecular conformations by building on the recently…

Quantitative Methods · Quantitative Biology 2024-04-23 Romain Lacombe , Neal Vaidya

Knowledge distillation can lead to deploy-friendly networks against the plagued computational complexity problem, but previous methods neglect the feature hierarchy in detectors. Motivated by this, we propose a general framework for…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Yangyang Qin , Hefei Ling , Zhenghai He , Yuxuan Shi , Lei Wu

Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hindered by the limited availability of paired histology-genomics data. Knowledge distillation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yongxin Guo , Hao Lu , Onur C. Koyun , Zhengjie Zhu , Muhammet Fatih Demir , Metin Nafi Gurcan

The deep complex convolution recurrent network (DCCRN) achieves excellent speech enhancement performance by utilizing the audio spectrum's complex features. However, it has a large number of model parameters. We propose a smaller model,…

Sound · Computer Science 2024-08-09 Runduo Han , Weiming Xu , Zihan Zhang , Mingshuai Liu , Lei Xie

Discrete diffusion has emerged as a powerful framework for generative modeling in discrete domains, yet efficiently sampling from these models remains challenging. Existing sampling strategies often struggle to balance computation and…

Machine Learning · Computer Science 2025-11-12 Yixiu Zhao , Jiaxin Shi , Feng Chen , Shaul Druckmann , Lester Mackey , Scott Linderman

Distilling latent diffusion models (LDMs) into ones that are fast to sample from is attracting growing research interest. However, the majority of existing methods face two critical challenges: (1) They hinge on long training using a huge…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Qingsong Xie , Zhenyi Liao , Zhijie Deng , Chen chen , Haonan Lu

As the size of pre-trained speech recognition models increases, running these large models in low-latency or resource-constrained environments becomes challenging. In this work, we leverage pseudo-labelling to assemble a large-scale…

Computation and Language · Computer Science 2023-11-02 Sanchit Gandhi , Patrick von Platen , Alexander M. Rush

Dataset distillation (DD) aims to generate a compact yet informative dataset that achieves performance comparable to the original dataset, thereby reducing demands on storage and computational resources. Although diffusion models have made…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Yawen Zou , Guang Li , Zi Wang , Chunzhi Gu , Chao Zhang

Speculative decoding (SD) accelerates large language model inference by employing a faster draft model for generating multiple tokens, which are then verified in parallel by the larger target model, resulting in the text generated according…

We tackle the challenging issue of aggressive fine-tuning encountered during the process of transfer learning of pre-trained language models (PLMs) with limited labeled downstream data. This problem primarily results in a decline in…

Computation and Language · Computer Science 2023-12-13 Ibtihel Amara , Vinija Jain , Aman Chadha

Acquiring genomes at single-cell resolution has many applications such as in the study of microbiota. However, deep sequencing and assembly of all of millions of cells in a sample is prohibitively costly. A property that can come to rescue…

Genomics · Quantitative Biology 2014-04-29 Zeinab Taghavi

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Inverse protein folding, the process of designing sequences that fold into a specific 3D structure, is crucial in bio-engineering and drug discovery. Traditional methods rely on experimentally resolved structures, but these cover only a…

Biomolecules · Quantitative Biology 2023-11-27 Igor Melnyk , Aurelie Lozano , Payel Das , Vijil Chenthamarakshan

Abstract. The advancement of deep learning has coincided with the proliferation of both models and available data. The surge in dataset sizes and the subsequent surge in computational requirements have led to the development of the Dataset…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Jun-Yeong Moon , Jung Uk Kim , Gyeong-Moon Park

We propose an efficient way to output better calibrated uncertainty scores from neural networks. The Distilled Dropout Network (DDN) makes standard (non-Bayesian) neural networks more introspective by adding a new training loss which…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Corina Gurau , Alex Bewley , Ingmar Posner

Diffusion Models (DMs), also referred to as score-based diffusion models, utilize neural networks to specify score functions. Unlike most other probabilistic models, DMs directly model the score functions, which makes them more flexible to…

Machine Learning · Computer Science 2023-04-11 Weijian Luo

Metagenomic taxonomic annotation aims to identify the microbial origins of DNA fragments in environmental samples. Traditional methods that rely on sequence similarity are often constrained by the high microbial diversity and the…

Machine Learning · Computer Science 2026-05-29 Rongye Ye , Lun Li , Zheng Luo , Yiran Zhan , Shuhui Song

It is currently difficult to distill discrete diffusion models. In contrast, continuous diffusion literature has many distillation approaches methods that can reduce sampling steps to a handful. Our method, Discrete Moment Matching…

Machine Learning · Computer Science 2026-03-23 Emiel Hoogeboom , David Ruhe , Jonathan Heek , Thomas Mensink , Tim Salimans

Motivation: Histone modifications are among the most important factors that control gene regulation. Computational methods that predict gene expression from histone modification signals are highly desirable for understanding their…

Machine Learning · Computer Science 2016-07-08 Ritambhara Singh , Jack Lanchantin , Gabriel Robins , Yanjun Qi