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Related papers: A Review of Deep Learning Techniques for Protein F…

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Since about 100 years ago, to learn the intrinsic structure of data, many representation learning approaches have been proposed, including both linear ones and nonlinear ones, supervised ones and unsupervised ones. Particularly, deep…

Machine Learning · Computer Science 2016-11-28 Guoqiang Zhong , Li-Na Wang , Junyu Dong

Deep learning has received extensive research interest in developing new medical image processing algorithms, and deep learning based models have been remarkably successful in a variety of medical imaging tasks to support disease detection…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Xuxin Chen , Ximin Wang , Ke Zhang , Kar-Ming Fung , Theresa C. Thai , Kathleen Moore , Robert S. Mannel , Hong Liu , Bin Zheng , Yuchen Qiu

Enzyme mining is rapidly evolving as a data-driven strategy to identify biocatalysts with tailored functions from the vast landscape of uncharacterized proteins. The integration of machine learning into these workflows enables…

Biomolecules · Quantitative Biology 2025-07-11 Yanzi Zhang , Felix Moorhoff , Sizhe Qiu , Wenjuan Dong , David Medina-Ortiz , Jing Zhao , Mehdi D. Davari

Our goal is to provide a review of deep learning methods which provide insight into structured high-dimensional data. Rather than using shallow additive architectures common to most statistical models, deep learning uses layers of…

Machine Learning · Statistics 2023-10-11 Nick Polson , Vadim Sokolov

As protein informatics advances rapidly, the demand for enhanced predictive accuracy, structural analysis, and functional understanding has intensified. Transformer models, as powerful deep learning architectures, have demonstrated…

Machine Learning · Computer Science 2025-05-28 Xiaowen Ling , Zhiqiang Li , Yanbin Wang , Zhuhong You

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong

Advancements in artificial intelligence, machine learning, and deep learning have catalyzed the transformation of big data analytics and management into pivotal domains for research and application. This work explores the theoretical…

Multimodal protein features play a crucial role in protein function prediction. However, these features encompass a wide range of information, ranging from structural data and sequence features to protein attributes and interaction…

Machine Learning · Computer Science 2025-11-07 Xiaoling Luo , Peng Chen , Chengliang Liu , Xiaopeng Jin , Jie Wen , Yumeng Liu , Junsong Wang

Deep Learning has driven recent and exciting progress in computer vision, instilling the belief that these algorithms could solve any visual task. Yet, datasets commonly used to train and test computer vision algorithms have pervasive…

Computer Vision and Pattern Recognition · Computer Science 2020-04-01 Vincent Jacquot , Zhuofan Ying , Gabriel Kreiman

Deep learning based on artificial neural networks is a powerful machine learning method that, in the last few years, has been successfully used to realize tasks, e.g., image classification, speech recognition, translation of languages,…

Information Theory · Computer Science 2019-06-18 Alessio Zappone , Marco Di Renzo , Mérouane Debbah , Thanh Tu Lam , Xuewen Qian

The rise of deep learning has marked significant progress in fields such as computer vision, natural language processing, and medical imaging, primarily through the adaptation of pre-trained models for specific tasks. Traditional…

Machine Learning · Computer Science 2024-04-25 Charith Chandra Sai Balne , Sreyoshi Bhaduri , Tamoghna Roy , Vinija Jain , Aman Chadha

As the complexity and dynamism of financial markets continue to grow, traditional financial risk prediction methods increasingly struggle to handle large datasets and intricate behavior patterns. This paper explores the feasibility and…

Machine Learning · Computer Science 2024-12-24 Haowei Yang , Zhan Cheng , Zhaoyang Zhang , Yuanshuai Luo , Shuaishuai Huang , Ao Xiang

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein function or structure. Existing approaches usually pretrain protein language models on a large number of unlabeled amino acid…

Machine Learning · Computer Science 2023-01-31 Zuobai Zhang , Minghao Xu , Arian Jamasb , Vijil Chenthamarakshan , Aurelie Lozano , Payel Das , Jian Tang

The ability to anticipate possible future human actions is essential for a wide range of applications, including autonomous driving and human-robot interaction. Consequently, numerous methods have been introduced for action anticipation in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Zeyun Zhong , Manuel Martin , Michael Voit , Juergen Gall , Jürgen Beyerer

Deep learning based forecasting methods have become the methods of choice in many applications of time series prediction or forecasting often outperforming other approaches. Consequently, over the last years, these methods are now…

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

In the current landscape of deep learning research, there is a predominant emphasis on achieving high predictive accuracy in supervised tasks involving large image and language datasets. However, a broader perspective reveals a multitude of…

As an important data selection schema, active learning emerges as the essential component when iterating an Artificial Intelligence (AI) model. It becomes even more critical given the dominance of deep neural network based models, which are…

Machine Learning · Computer Science 2022-12-27 Rinyoichi Takezoe , Xu Liu , Shunan Mao , Marco Tianyu Chen , Zhanpeng Feng , Shiliang Zhang , Xiaoyu Wang