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In cancer research, the comparison of gene expression or DNA methylation networks inferred from healthy controls and patients can lead to the discovery of biological pathways associated to the disease. As a cancer progresses, its signalling…

Methodology · Statistics 2015-06-17 Da Ruan , Alastair Young , Giovanni Montana

Deep Gaussian processes (DGPs) are multi-layer hierarchical generalisations of Gaussian processes (GPs) and are formally equivalent to neural networks with multiple, infinitely wide hidden layers. DGPs are nonparametric probabilistic models…

The increasing availability of high-dimensional, longitudinal measures of gene expression can facilitate understanding of biological mechanisms, as required for precision medicine. Biological knowledge suggests that it may be best to…

Applications · Statistics 2025-04-18 Jiachen Cai , Robert J. B. Goudie , Colin Starr , Brian D. M. Tom

Using machine learning, we explore the utility of various deep neural networks (NN) when applied to high harmonic generation (HHG) scenarios. First, we train the NNs to predict the time-dependent dipole and spectra of HHG emission from…

Optics · Physics 2023-03-07 M. Lytova , M. Spanner , I. Tamblyn

Multiscale partial differential equations (PDEs) arise in various applications, and several schemes have been developed to solve them efficiently. Homogenization theory is a powerful methodology that eliminates the small-scale dependence,…

Numerical Analysis · Mathematics 2024-01-08 Kaushik Bhattacharya , Nikola Kovachki , Aakila Rajan , Andrew M. Stuart , Margaret Trautner

Models (i.e., governing equations) are fundamental to science and engineering. Advances in data acquisition now make it possible to extract interpretable, low dimensional descriptions from high dimensional observations. However, existing…

Quantitative Methods · Quantitative Biology 2026-05-19 Michael C. Chung , Tarran Mohan , Purushottam D. Dixit , Juan Guan

Social networks are considered to be heterogeneous graph neural networks (HGNNs) with deep learning technological advances. HGNNs, compared to homogeneous data, absorb various aspects of information about individuals in the training stage.…

Machine Learning · Computer Science 2022-10-11 Yuecen Wei , Xingcheng Fu , Qingyun Sun , Hao Peng , Jia Wu , Jinyan Wang , Xianxian Li

Given an orthonormal basis in a $d$-dimensional Hilbert space and a unital quantum operation $\cal E$ acting on it one can define a non-linear mapping that associates to $\cal E$ a $d\times d$ real-valued matrix that we call the Coherence…

Quantum Physics · Physics 2017-05-10 Paolo Zanardi , Georgios Styliaris , Lorenzo Campos Venuti

Matching 2D keypoints in an image to a sparse 3D point cloud of the scene without requiring visual descriptors has garnered increased interest due to its low memory requirements, inherent privacy preservation, and reduced need for expensive…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Shuzhe Wang , Juho Kannala , Daniel Barath

Despite the widespread utilization of Gaussian process models for versatile nonparametric modeling, they exhibit limitations in effectively capturing abrupt changes in function smoothness and accommodating relationships with heteroscedastic…

Machine Learning · Statistics 2023-09-01 Taehee Lee , Jun S. Liu

We have developed a new data-driven paradigm for the rapid inference, modeling and simulation of the physics of transport phenomena by deep learning. Using conditional generative adversarial networks (cGAN), we train models for the direct…

Machine Learning · Computer Science 2017-09-11 Amir Barati Farimani , Joseph Gomes , Vijay S. Pande

We develop a high-order hybridized discontinuous Galerkin (HDG) method for a linear degenerate elliptic equation arising from a two-phase mixture of mantle convection or glacier dynamics. We show that the proposed HDG method is well-posed…

Computational Engineering, Finance, and Science · Computer Science 2019-05-01 Shinhoo Kang , Tan Bui-Thanh , Todd Arbogast

Most existing approaches to clustering gene expression time course data treat the different time points as independent dimensions and are invariant to permutations, such as reversal, of the experimental time course. Approaches utilizing…

Machine Learning · Computer Science 2012-07-02 Matthew Beal , Praveen Krishnamurthy

In the era of generative AI, deep generative models (DGMs) with latent representations have gained tremendous popularity. Despite their impressive empirical performance, the statistical properties of these models remain underexplored. DGMs…

Machine Learning · Statistics 2025-08-07 Seunghyun Lee , Yuqi Gu

Probabilistic graphical modeling (PGM) provides a framework for formulating an interpretable generative process of data and expressing uncertainty about unknowns, but it lacks flexibility. Deep learning (DL) is an alternative framework for…

Machine Learning · Statistics 2021-04-27 Adji B. Dieng

Delay-coordinates dynamic mode decomposition (DC-DMD) is widely used to extract coherent spatiotemporal modes from high-dimensional time series. A central challenge is distinguishing dynamically meaningful modes from spurious modes induced…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Yoav Harris , Hadas Benisty , Ronen Talmon

This paper introduces a differential dynamic programming (DDP) based framework for polynomial trajectory generation for differentially flat systems. In particular, instead of using a linear equation with increasing size to represent…

Optimization and Control · Mathematics 2021-09-13 Kun Cao , Muqing Cao , Shenghai Yuan , Lihua Xie

Data-driven science and computation have advanced immensely to construct complex functional relationships using trainable parameters. However, efficiently discovering interpretable and accurate closed-form expressions from complex dataset…

Machine Learning · Computer Science 2026-03-17 Reza T. Batley , Chanwook Park , Wing Kam Liu , Sourav Saha

Practical applications of mechanical metamaterials often involve solving inverse problems where the objective is to find the (multiple) microarchitectures that give rise to a given set of properties. The limited resolution of additive…

Text-to-image generation models have achieved remarkable capabilities in synthesizing images, but often struggle to provide fine-grained control over the output. Existing guidance approaches, such as segmentation maps and depth maps,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Sangmin Jung , Utkarsh Nath , Yezhou Yang , Giulia Pedrielli , Joydeep Biswas , Amy Zhang , Hassan Ghasemzadeh , Pavan Turaga
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