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In randomized trials, repeated measures of the outcome are routinely collected. The mixed model for repeated measures (MMRM) leverages the information from these repeated outcome measures, and is often used for the primary analysis to…

Methodology · Statistics 2023-07-20 Bingkai Wang , Yu Du

A model-assisted semiparametric method of estimating finite population totals is investigated to improve the precision of survey estimators by incorporating multivariate auxiliary information. The proposed superpopulation model is a…

Methodology · Statistics 2019-03-19 Lily Wang

This study proposes a novel method for estimation and hypothesis testing in high-dimensional single-index models. We address a common scenario where the sample size and the dimension of regression coefficients are large and comparable.…

Statistics Theory · Mathematics 2024-04-30 Kazuma Sawaya , Yoshimasa Uematsu , Masaaki Imaizumi

In a regression analysis, suppose we suspect that there are several heterogeneous groups in the population that a sample represents. Mixture regression models have been applied to address such problems. By modeling the conditional…

Methodology · Statistics 2013-07-02 Toshiya Hoshikawa

The aim of this paper is to present a mixture composite regression model for claim severity modelling. Claim severity modelling poses several challenges such as multimodality, heavy-tailedness and systematic effects in data. We tackle this…

Methodology · Statistics 2021-08-02 Tsz Chai Fung , George Tzougas , Mario Wuthrich

Modeling clustered/correlated failure time data has been becoming increasingly important in clinical trials and epidemiology studies. In this paper, we consider a semiparametric marginal promotion time cure model for clustered…

Methodology · Statistics 2025-05-15 Fei Xiao , Yingwei Peng , Dipankar Bandyopadhyayd , Yi Niu

Survival analysis aims to explore the relationship between covariates and the time until the occurrence of an event. The Cox proportional hazards model is commonly used for right-censored data, but it is not strictly limited to this type of…

Methodology · Statistics 2025-07-02 Abdoulaye Dioni , Lynne Moore , Aida Eslami

Regression analyses based on transformations of cumulative incidence functions are often adopted when modeling and testing for treatment effects in clinical trial settings involving competing and semi-competing risks. Common frameworks…

Methodology · Statistics 2024-01-11 Alexandra Bühler , Richard J Cook , Jerald F Lawless

The proportional hazards assumption in the commonly used Cox model for censored failure time data is often violated in scientific studies. Yang and Prentice (2005) proposed a novel semiparametric two-sample model that includes the…

Methodology · Statistics 2012-06-06 Guoqing Diao , Donglin Zeng , Song Yang

A nonparametric latency estimator for mixture cure models is studied in this paper. An i.i.d. representation is obtained, the asymptotic mean squared error of the latency estimator is found, and its asymptotic normality is proven. A…

Methodology · Statistics 2024-01-31 Ana López-Cheda , M. Amalia Jácome , Ricardo Cao

We study mixed models with a single grouping factor, where inference about unknown parameters requires optimizing a marginal likelihood defined by an intractable integral. Low-dimensional numerical integration techniques are regularly used…

Methodology · Statistics 2025-01-22 Alex Stringer , Blair Bilodeau , Yanbo Tang

We study convergence properties of competing epidemic models of the Susceptible-Infected-Susceptible (SIS) type. The SIS epidemic model has seen widespread popularity in modelling the spreading dynamics of contagions such as viruses,…

Systems and Control · Electrical Eng. & Systems 2022-10-12 Vishwaraj Doshi , Shailaja Mallick , Do Young eun

Motivated by the need to analyze continuously updated data sets in the context of time-to-event modeling, we propose a novel nonparametric approach to estimate the conditional hazard function given a set of continuous and discrete…

Methodology · Statistics 2025-07-03 Daphné Aurouet , Valentin Patilea

Consider a subject or unit in a longitudinal biomedical, public health, engineering, economic, or social science study which is being monitored over a possibly random duration. Over time this unit experiences competing recurrent events and…

Methodology · Statistics 2024-12-30 Lili Tong , Piaomu Liu , Edsel Pena

We consider the estimation of average treatment effects in observational studies and propose a new framework of robust causal inference with unobserved confounders. Our approach is based on distributionally robust optimization and proceeds…

Methodology · Statistics 2023-02-06 Dimitris Bertsimas , Kosuke Imai , Michael Lingzhi Li

This paper presents an original approach for jointly fitting survival times and classifying samples into subgroups. The Coxlogit model is a generalized linear model with a common set of selected features for both tasks. Survival times and…

Machine Learning · Statistics 2015-02-06 Samuel Branders , Roberto D'Ambrosio , Pierre Dupont

Clustered data, which arise when observations are nested within groups, are incredibly common in clinical, education, and social science research. Traditionally, a linear mixed model, which includes random effects to account for…

Methodology · Statistics 2026-02-04 Kevin McCoy , Zachary Wooten , Katarzyna Tomczak , Christine B. Peterson

In this paper, we propose a flexible cure rate model with frailty term in latent risk, which is obtained by incorporating a frailty term in risk function of latent competing causes. The number of competing causes of the event of interest…

Assessment of multistate disease progression is commonplace in biomedical research, such as, in periodontal disease (PD). However, the presence of multistate current status endpoints, where only a single snapshot of each subject's…

Methodology · Statistics 2025-09-03 Snigdha Das , Minwoo Chae , Debdeep Pati , Dipankar Bandyopadhyay

Many causal estimands are only partially identifiable since they depend on the unobservable joint distribution between potential outcomes. Stratification on pretreatment covariates can yield sharper bounds; however, unless the covariates…

Econometrics · Economics 2024-11-19 Wenlong Ji , Lihua Lei , Asher Spector