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Explainability domain generalization and rare class reliability are critical challenges in medical AI where deep models often fail under real world distribution shifts and exhibit bias against infrequent clinical conditions This paper…

Artificial Intelligence · Computer Science 2026-01-06 Midhat Urooj , Ayan Banerjee , Sandeep Gupta

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Artificial intelligence now outperforms humans in several scientific and engineering tasks, yet its internal representations often remain opaque. In this Perspective, we argue that explainable artificial intelligence (XAI), combined with…

Artificial Intelligence · Computer Science 2026-02-17 Ricardo Vinuesa , Steven L. Brunton , Gianmarco Mengaldo

With the increasing adoption of Artificial Intelligence (AI) systems in high-stake domains, such as healthcare, effective collaboration between domain experts and AI is imperative. To facilitate effective collaboration between domain…

Human-Computer Interaction · Computer Science 2024-05-24 Aditya Bhattacharya , Simone Stumpf , Katrien Verbert

Artificial intelligence-driven adaptive learning systems are reshaping education through data-driven adaptation of learning experiences. Yet many of these systems lack transparency, offering limited insight into how decisions are made. Most…

Artificial Intelligence · Computer Science 2025-08-04 Maryam Mosleh , Marie Devlin , Ellis Solaiman

The adoption of machine learning in high-stakes applications such as healthcare and law has lagged in part because predictions are not accompanied by explanations comprehensible to the domain user, who often holds the ultimate…

The lack of explainability of a decision from an Artificial Intelligence (AI) based "black box" system/model, despite its superiority in many real-world applications, is a key stumbling block for adopting AI in many high stakes applications…

Artificial Intelligence · Computer Science 2021-01-26 Sheikh Rabiul Islam , William Eberle , Sheikh Khaled Ghafoor , Mohiuddin Ahmed

Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for…

Deep learning bears promise for drug discovery, including advanced image analysis, prediction of molecular structure and function, and automated generation of innovative chemical entities with bespoke properties. Despite the growing number…

Artificial Intelligence · Computer Science 2020-07-03 José Jiménez-Luna , Francesca Grisoni , Gisbert Schneider

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Interest in the field of Explainable Artificial Intelligence has been growing for decades and has accelerated recently. As Artificial Intelligence models have become more complex, and often more opaque, with the incorporation of complex…

Artificial Intelligence · Computer Science 2020-03-18 Shruthi Chari , Daniel M. Gruen , Oshani Seneviratne , Deborah L. McGuinness

Fairness of machine learning models in healthcare has drawn increasing attention from clinicians, researchers, and even at the highest level of government. On the other hand, the importance of developing and deploying interpretable or…

Machine Learning · Computer Science 2024-09-04 Mary M. Lucas , Xiaoyang Wang , Chia-Hsuan Chang , Christopher C. Yang , Jacqueline E. Braughton , Quyen M. Ngo

The development of AI-driven generative audio mirrors broader AI trends, often prioritizing immediate accessibility at the expense of explainability. Consequently, integrating such tools into sustained artistic practice remains a…

Sound · Computer Science 2024-07-23 Austin Tecks , Thomas Peschlow , Gabriel Vigliensoni

Explainable Artificial Intelligence (AI) focuses on helping humans understand the working of AI systems or their decisions and has been a cornerstone of AI for decades. Recent research in explainability has focused on explaining the…

Artificial Intelligence · Computer Science 2024-10-24 Shruthi Chari

Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller

Artificial Intelligence (AI) is rapidly integrating into various aspects of our daily lives, influencing decision-making processes in areas such as targeted advertising and matchmaking algorithms. As AI systems become increasingly…

Artificial Intelligence · Computer Science 2025-03-11 Md. Tanzib Hosain , Mehedi Hasan Anik , Sadman Rafi , Rana Tabassum , Khaleque Insia , Md. Mehrab Siddiky

Despite promising developments in Explainable Artificial Intelligence, the practical value of XAI methods remains under-explored and insufficiently validated in real-world settings. Robust and context-aware evaluation is essential, not only…

Human-Computer Interaction · Computer Science 2025-06-18 Ivania Donoso-Guzmán , Kristýna Sirka Kacafírková , Maxwell Szymanski , An Jacobs , Denis Parra , Katrien Verbert

AI is transforming the healthcare domain and is increasingly helping practitioners to make health-related decisions. Therefore, accountability becomes a crucial concern for critical AI-driven decisions. Although regulatory bodies, such as…

Artificial Intelligence · Computer Science 2025-09-04 Prachi Bagave , Marcus Westberg , Marijn Janssen , Aaron Yi Ding

Black-box nature of Artificial Intelligence (AI) models do not allow users to comprehend and sometimes trust the output created by such model. In AI applications, where not only the results but also the decision paths to the results are…

Artificial Intelligence · Computer Science 2024-10-28 Ibrahim Kok , Feyza Yildirim Okay , Ozgecan Muyanli , Suat Ozdemir

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on…

Artificial Intelligence · Computer Science 2024-01-17 Haoyi Xiong , Xuhong Li , Xiaofei Zhang , Jiamin Chen , Xinhao Sun , Yuchen Li , Zeyi Sun , Mengnan Du
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