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Related papers: Extending SIRS epidemics to allow for gradual wani…

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We analyse an extended SIRS epidemic model in which immunity at the individual level wanes gradually at exponential rate, but where the waning rate may differ between individuals, for instance as an effect of differences in immune systems.…

Populations and Evolution · Quantitative Biology 2023-11-02 Mohamed El Khalifi , Tom Britton

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

SIRS models capture transmission dynamics of infectious diseases for which immunity is not lifelong. Extending these models by a W compartment for individuals with waning immunity, the boosting of the immune system upon repeated exposure…

Populations and Evolution · Quantitative Biology 2022-01-19 Richmond Opoku-Sarkodie , Ferenc A. Bartha , Mónika Polner , Gergely Röst

We propose a model of the immunity to a cyclical epidemic disease taking account not only of seasonal boosts during the infectious season, but also of residual immunity remaining from one season to the next. The focus is on the exponential…

Populations and Evolution · Quantitative Biology 2024-04-22 Siyu Chen , David Sankoff

An SEIRS epidemic with disease fatalities is introduced in a growing population (modelled as a super-critical linear birth and death process). The study of the initial phase of the epidemic is stochastic, while the analysis of the major…

Populations and Evolution · Quantitative Biology 2017-03-29 Tom Britton , Désiré Ouédraogo

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment…

Dynamical Systems · Mathematics 2014-11-13 Maria Vittoria Barbarossa , Gergely Röst

When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again.…

Populations and Evolution · Quantitative Biology 2015-01-15 Maria Vittoria Barbarossa , Gergely Röst

This is an epidemiological SIRV model based study that is designed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recovered and vaccinated…

Populations and Evolution · Quantitative Biology 2018-11-14 Ewa Grela , Michael Stich , Amit K Chattopadhyay

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

Physics and Society · Physics 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco

We analyze the susceptible-infected-susceptible model for epidemic spreading in which a fraction of the individuals become immune by vaccination. This process is understood as a dilution by vaccination, which decreases the fraction of the…

Populations and Evolution · Quantitative Biology 2021-11-10 Tânia Tomé , Mário J. de Oliveira

We consider an epidemiological model that includes waning and boosting of immunity. Assuming that repeated exposure to the pathogen fully restores immunity, we derive an SIRS-type model with discrete and distributed delays. First we prove…

Dynamical Systems · Mathematics 2016-06-14 Maria Vittoria Barbarossa , Monika Polner , Gergely Röst

We study a SEIR model considered by Gomes et al. \cite{Gomes2020} and Aguas et al. \cite{Aguas2020} where different individuals are assumed to have different levels of susceptibility or exposure to infection. Under this heterogeneity…

Populations and Evolution · Quantitative Biology 2022-05-10 Antonio Montalbán , Rodrigo M. Corder , M. Gabriela M. Gomes

We study the influence of the rate of the attainment of herd immunity (HI), in the absence of an approved vaccine, on the vulnerable population. We essentially ask the question: how hard the evolution towards the desired herd immunity could…

Populations and Evolution · Quantitative Biology 2020-06-01 Sayantan Mondal , Saumyak Mukherjee , Biman Bagchi

In a seminal work, Chatterjee and Durrett (2009) established that for the SIS epidemic process on random graphs with power-law degree distributions, the infection survives for an exponentially long time (in the network size) for any fixed,…

Probability · Mathematics 2026-04-28 Zihao He , Souvik Dhara , Debankur Mukherjee

COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as…

Populations and Evolution · Quantitative Biology 2022-08-26 V. R. Saiprasad , R. Gopal , V. K. Chandrasekar , M. Lakshmanan

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We study the phase transition from the persistence phase to the extinction phase for the SIRS (susceptible/ infected/ refractory/ susceptible) model of diseases spreading on the networks. We derive an analytical expression of the…

Populations and Evolution · Quantitative Biology 2019-11-18 M. Ali Saif

Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity. In some disease systems, the process of waning immunity can be…

Populations and Evolution · Quantitative Biology 2017-08-10 Tiffany Leung , Barry D Hughes , Federico Frascoli , Patricia T Campbell , James M McCaw

We investigate final outcome properties of an SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than…

Probability · Mathematics 2024-04-08 Frank Ball , David Sirl , Pieter Trapman
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