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This paper studies the spread dynamics of a stochastic SIRS epidemic model with nonlinear incidence and varying population size, which is formulated as a piecewise deterministic Markov process. A threshold dynamic determined by the basic…

Dynamical Systems · Mathematics 2017-10-26 Dan Li , Shengqiang Liu , Jing'an Cui

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

This paper is concerned with the robustness of the sustained oscillations predicted by an epidemic ODE model defined on contact networks. The model incorporates the spread of awareness among individuals and, moreover, a small inflow of…

Populations and Evolution · Quantitative Biology 2020-11-11 David Juher , David Rojas , Joan Saldaña

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

The U.S. Covid-19 data exhibit a high-frequency oscillation along a low-frequency wave for outbreaks. There is no model to account for it. A modified SIR model is proposed to explain this spiking phenomenon. It is also used to best-fit the…

Populations and Evolution · Quantitative Biology 2023-11-21 Bo Deng

Covid-19 is one of the most dreaded pandemics/epidemics in the world threatening the human population. The dynamics of this pandemic is quite complicated and prediction of pandemic states often fails. In this work, we study and correlate…

Populations and Evolution · Quantitative Biology 2021-10-06 Jyoti Bhadana , R. K. Brojen Singh

This paper deals with a new epidemiological model of SIRS with stochastic perturbations. The primary objective is to establish the existence of a unique non-negative nonlocal solution. Using the basic reproduction number $\mathscr{R}_0$…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt

An SIRS type model of disease transmission in an open environment is discussed. We use the Poincar\'{e} index together with a perturbation method to show that the endemic proportions need not be unique.

Classical Analysis and ODEs · Mathematics 2007-05-23 M. R. Razvan

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We study the susceptible-infective-recovered (SIR) epidemic on a random graph chosen uniformly subject to having given vertex degrees. In this model infective vertices infect each of their susceptible neighbours, and recover, at a constant…

Probability · Mathematics 2014-09-24 Svante Janson , Malwina Luczak , Peter Windridge

The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…

Populations and Evolution · Quantitative Biology 2022-07-20 Matthijs Meijers , Denis Ruchnewitz , Marta Łuksza , Michael Lässig

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

Populations and Evolution · Quantitative Biology 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

We introduce a minimal multiscale framework that links within-host virus dynamics to population-level SIRS epidemiology through explicit, bidirectional coupling. At the microscopic layer, a two variant quasispecies (master and mutant…

Dynamical Systems · Mathematics 2026-01-28 Juan C. Muñoz-Sánchez , J. Tomás Lázaro , Josep Sardanyés , Santiago F. Elena

This paper utilizes a stochastic Susceptible-Infected-recovered (SIR) model with a non-linear incidence rate to perform a detailed mathematical study of optimal lock-down intensity and vaccination rate under the COVID-19 pandemic…

Optimization and Control · Mathematics 2022-09-29 Paramahansa Pramanik

The susceptible-infectious-recovered (SIR) model describes the evolution of three species of individuals which are subject to an infection and recovery mechanism. A susceptible $S$ can become infectious with an infection rate $\beta$ by an…

Statistical Mechanics · Physics 2008-06-30 Gunter M. Schütz , Marian Brandau , Steffen Trimper

We study the threshold dynamics of a stochastic SAIRS-type model with vaccination, where the role of asymptomatic and symptomatic infectious individuals is explicitly considered in the epidemic dynamics. In the model, the values of the…

Probability · Mathematics 2023-03-03 Stefania Ottaviano

We introduce an extension to Kermack and McKendrick's classic susceptible-infected-recovered (SIR) model in epidemiology, whose underlying mechanism of infection consists of individuals attending randomly generated social gatherings. This…

Probability · Mathematics 2024-05-08 Roberto Cortez

The aim of this study is to propose a modified Susceptible-Exposed-Infectious-Removed (SEIR) model that describes the behaviour of symptomatic, asymptomatic and hospitalized patients of COVID-19 epidemic, including the effect of demographic…

In this paper, we consider a reaction-diffusion-advection SIS epidemic model with saturated incidence rate and linear source. We study the uniform bounds of parabolic system and some asymptotic behavior of the basic reproduction number…

Analysis of PDEs · Mathematics 2024-06-26 Qi Wang

With the present highly infectious dominant SARS-CoV-2 strain of B1.1.529 or Omicron spreading around the globe, there is concern that the COVID-19 pandemic will not end soon and that it will be a race against time until a more contagious…

Populations and Evolution · Quantitative Biology 2022-04-26 Chottiwatt Jittprasong
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