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Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu

Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Yingkai Zhang , Shuang Chen , Ye Tian , Yunyi Gao , Jianyong Jiang , Ying Fu

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Snehashis Roy , John A. Butman , Dzung L. Pham

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Accurate quantification of tau pathology via tau positron emission tomography (PET) scan is crucial for diagnosing and monitoring Alzheimer's disease (AD). However, the high cost and limited availability of tau PET restrict its widespread…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yuxin Gong , Se-in Jang , Wei Shao , Yi Su , Kuang Gong

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…

Low-field to high-field MRI synthesis has emerged as a cost-effective strategy to enhance image quality under hardware and acquisition constraints, particularly in scenarios where access to high-field scanners is limited or impractical.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Zhenxuan Zhang , Peiyuan Jing , Ruicheng Yuan , Liwei Hu , Anbang Wang , Fanwen Wang , Yinzhe Wu , Kh Tohidul Islam , Zhaolin Chen , Zi Wang , Peter Lally , Guang Yang

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Neurological Positron Emission Tomography (PET) is a critical imaging modality for diagnosing and studying neurodegenerative diseases like Alzheimer's disease. However, the inherent low spatial resolution of PET images poses significant…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Quanzheng Li

Segmentation of brain structures from MRI is crucial for evaluating brain morphology, yet existing CNN and transformer-based methods struggle to delineate complex structures accurately. While current diffusion models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qilong Xing , Zikai Song , Yuteng Ye , Yuke Chen , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Fang-Cheng Yeh

Magnetic resonance imaging (MRI) requires long acquisition times, raising costs, reducing accessibility, and making scans more susceptible to motion artifacts. Diffusion probabilistic models that learn data-driven priors can potentially…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Rohan Sanda , Asad Aali , Andrew Johnston , Eduardo Reis , Gordon Wetzstein , Sara Fridovich-Keil

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Alzheimer's disease (AD) is the most common cause of dementia. An early detection is crucial for slowing down the disease and mitigating risks related to the progression. While the combination of MRI and FDG-PET is the best image-based tool…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Marcel Kollovieh , Matthias Keicher , Stephan Wunderlich , Hendrik Burwinkel , Thomas Wendler , Nassir Navab

Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) automatic 3-D registration is implemented and validated for small animal image volumes so that the high-resolution anatomical MRI information can be fused with the low…

Computer Vision and Pattern Recognition · Computer Science 2017-05-24 Nathanael L. Baisa , Stéphanie Bricq , Alain Lalande

Ultra-low-field (ULF) MRI offers portable and accessible neuroimaging but suffers from reduced signal-to-noise ratio and limited spatial resolution compared to high-field (HF) systems. Acquiring paired ULF-HF data for supervised enhancement…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Toufiq Musah , Salvatore Calcagno , Federica Proietto Salanitri , Xiaomeng Li , Maruf Adewole , Marawan Elbatel

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

Structural MRI-to-amyloid PET synthesis has been proposed as a non-invasive alternative for amyloid assessment in Alzheimer's disease (AD). However, reported performance of identical models varies widely across studies, and increasingly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Louise E. G. Baron , Ross Callaghan , David M. Cash , Philip S. J. Weston , Hojjat Azadbakht , Hui Zhang