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Hippocampal place cells can encode spatial locations of an animal in physical or task-relevant spaces. We simulated place cell populations that encoded either Euclidean- or graph-based positions of a rat navigating to goal nodes in a maze…

Neurons and Cognition · Quantitative Biology 2022-11-17 Thibault Niederhauser , Adam Lester , Nina Miolane , Khanh Dao Duc , Manu S. Madhav

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

Quantitative Methods · Quantitative Biology 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

We propose to analyze dynamically changing brain networks by decomposing them into three orthogonal components through the Hodge decomposition. We propose to quantify the magnitude and relative strength of each component. We performed…

Neurons and Cognition · Quantitative Biology 2025-07-23 D. Vijay Anand , Anass B El-Yaagoubi , Hernando Ombao , Moo K. Chung

Different classes of communication network topologies and their representation in the form of adjacency matrix and its eigenvalues are presented. A self-organizing feature map neural network is used to map different classes of communication…

Neural and Evolutionary Computing · Computer Science 2007-05-23 W. Ali , R. J. Mondragon , F. Alavi

We present an approach to inform the reconstruction of a surface from a point scan through topological priors. The reconstruction is based on basis functions which are optimized to provide a good fit to the point scan while satisfying…

Computational Geometry · Computer Science 2021-09-17 Rickard Brüel-Gabrielsson , Vignesh Ganapathi-Subramanian , Primoz Skraba , Leonidas J. Guibas

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Topological Deep Learning seeks to enhance the predictive performance of neural network models by harnessing topological structures in input data. Topological neural networks operate on spaces such as cell complexes and hypergraphs, that…

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

Neurons and Cognition · Quantitative Biology 2016-03-22 Yuri Dabaghian

Repeating patterns of spike sequences from a neuronal network have been proposed to be useful in the reconstruction of the network topology. Reverberations in a physiologically realistic model with various physical connection topologies…

Neurons and Cognition · Quantitative Biology 2014-07-15 Hao Song , Chun-Chung Chen , Jyh-Jang Sun , Pik-Yin Lai , C. K. Chan

The brain achieves stability and plasticity in a topologically complex, shifting world through Metric-Topology Factorization (MTF), separating discrete topological indexing for context selection from continuous metric condensation for local…

Neurons and Cognition · Quantitative Biology 2026-03-05 Xin Li

Despite significant advances in the field of deep learning in applications to various fields, explaining the inner processes of deep learning models remains an important and open question. The purpose of this article is to describe and…

Machine Learning · Computer Science 2022-04-20 German Magai , Anton Ayzenberg

Starting from the concept of binary interactions between pairs of particles, a kinetic framework for the description of the action potential dynamics on a neural network is proposed. It consists of two coupled levels: the description of a…

Biological Physics · Physics 2023-03-21 Martina Conte , Maria Groppi , Andrea Tosin

Autonomous navigation in complex and partially observable environments remains a central challenge in robotics. Several bio-inspired models of mapping and navigation based on place cells in the mammalian hippocampus have been proposed. This…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Bekarys Dukenbaev , Andrew Gerstenslager , Alexander Johnson , Ali A. Minai

Detecting and evaluating regions of brain under various circumstances is one of the most interesting topics in computational neuroscience. However, the majority of the studies on detecting communities of a functional connectivity network of…

Social and Information Networks · Computer Science 2018-06-04 Keivan Hassani Monfared , Kris Vasudevan , Jordan S. Farrell , G. Campbell Teskey

Brain networks/graphs derived from resting-state functional MRI (fMRI) help study underlying pathophysiology of neurocognitive disorders by measuring neuronal activities in the brain. Some studies utilize learning-based methods for brain…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Qianqian Wang , Wei Wang , Yuqi Fang , Hong-Jun Li , Andrea Bozoki , Mingxia Liu

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

Reconstructing human vision from brain activities has been an appealing task that helps to understand our cognitive process. Even though recent research has seen great success in reconstructing static images from non-invasive brain…

Computer Vision and Pattern Recognition · Computer Science 2023-05-22 Zijiao Chen , Jiaxin Qing , Juan Helen Zhou

The topology of the large-scale structure of the universe contains valuable information on the underlying cosmological parameters. While persistent homology can extract this topological information, the optimal method for parameter…

Cosmology and Nongalactic Astrophysics · Physics 2025-07-08 Jacky H. T. Yip , Adam Rouhiainen , Gary Shiu

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel
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