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Network architecture forms a critical constraint on neuronal function. Here we examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal…

Neurons and Cognition · Quantitative Biology 2016-08-02 Laura Wiles , Shi Gu , Fabio Pasqualetti , Danielle S. Bassett , David F. Meaney

The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…

Disordered Systems and Neural Networks · Physics 2022-08-03 Merav Stern , Nicolae Istrate , Luca Mazzucato

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

Neurons and Cognition · Quantitative Biology 2015-05-18 Xin Chen , Rhonda Dzakpasu

In neurosciences, the brain processes information via the firing patterns of connected neurons operating across a spectrum of frequencies. To better understand the effects of these frequencies in the neuron dynamics, we have simulated a…

Neurons and Cognition · Quantitative Biology 2025-11-21 Gabriel Marghoti , Thiago L. Prado , Miguel A. F. Sanjuán , Sergio R. Lopes

We study a mechanism of activity sustaining on networks inspired by a well-known model of neuronal dynamics. Our primary focus is the emergence of self-sustaining collective activity patterns, where no single node can stay active by itself,…

Physics and Society · Physics 2017-12-27 A. E. Allahverdyan , G. Ver Steeg , A. Galstyan

In this article, we report the development of an emerging dynamical state, namely, the alternating chimera, in a network of identical neuronal systems induced by an external electromagnetic field. Owing to this interaction scenario, the…

Adaptation and Self-Organizing Systems · Physics 2018-09-10 Soumen Majhi , Dibakar Ghosh

Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge…

Neurons and Cognition · Quantitative Biology 2019-11-12 Harang Ju , Jason Z. Kim , Danielle S. Bassett

Time-varying connections are crucial in understanding the structures and dynamics of complex networks. In this paper, we propose a continuous-time switching topology model for temporal networks that is driven by bursty behavior and study…

Physics and Society · Physics 2025-05-21 Ziyan Zeng , Minyu Feng , Matjaž Perc , Jürgen Kurths

Recent experimental observations have supported the hypothesis that the cerebral cortex operates in a dynamical regime near criticality, where the neuronal network exhibits a mixture of ordered and disordered patterns. However, A…

Neurons and Cognition · Quantitative Biology 2023-09-08 Longbin Zeng , Fengjian Feng , Wenlian Lu

The brain can learn to solve a wide range of tasks with high temporal and energetic efficiency. However, most biological models are composed of simple single compartment neurons and cannot achieve the state-of-art performances of artificial…

Neurons and Cognition · Quantitative Biology 2026-04-13 Cristiano Capone , Cosimo Lupo , Paolo Muratore , Pier Stanislao Paolucci

Multistability, the coexistence of multiple attractors in a dynamical system, is explored in bursting nerve cells. A modeling study is performed to show that a large class of bursting systems, as defined by a shared topology when…

Neurons and Cognition · Quantitative Biology 2010-06-29 J. P. Newman , R. J. Butera

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

Analysis of PDEs · Mathematics 2020-11-11 Grégory Dumont , Pierre Gabriel

Bursting oscillations are commonly seen as a mechanism for information coding in neuroscience and have also been observed in many physical, biochemical, and chemical systems. This study focuses on the computational investigation of…

Dynamical Systems · Mathematics 2021-10-15 Na Yu , Xuan Xia , Juan Liyau

New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered…

Neurons and Cognition · Quantitative Biology 2009-12-14 Casey M. Schneider-Mizell , Jack M. Parent , Eshel Ben-Jacob , Michal Zochowski , Leonard M. Sander

Turing instability in activator-inhibitor systems provides a paradigm of nonequilibrium pattern formation; it has been extensively investigated for biological and chemical processes. Turing pattern formation should furthermore be possible…

Adaptation and Self-Organizing Systems · Physics 2010-05-13 Hiroya Nakao , Alexander S. Mikhailov

Oscillations arise in many real-world systems and are associated with both functional and dysfunctional states. Whether a network can oscillate can be estimated if we know the strength of interaction between nodes. But in real-world…

Neurons and Cognition · Quantitative Biology 2023-11-16 Jie Zang , Shenquan Liu , Pascal Helson , Arvind Kumar

We use mean field theory to study the response properties of a simple randomly-connected model cortical network of leaky integrate-and-fire neurons with balanced excitation and inhibition. The formulation permits arbitrary temporal…

Disordered Systems and Neural Networks · Physics 2007-05-23 John Hertz , Barry Richmond , Kristian Nilsen

We report experimental studies of synchronization phenomena in a pair of biological neurons that interact through naturally occurring, electrical coupling. When these neurons generate irregular bursts of spikes, the natural coupling…

Records of social interactions provide us with new sources of data for understanding how interaction patterns affect collective dynamics. Such human activity patterns are often bursty, i.e., they consist of short periods of intense activity…

Physics and Society · Physics 2015-06-05 Taro Takaguchi , Naoki Masuda , Petter Holme

A perturbative method is developed for calculating the effects of recurrent synaptic interactions between neurons embedded in a network. A series expansion is constructed that converges for networks with noisy membrane potential and weak…

Disordered Systems and Neural Networks · Physics 2009-11-10 Patrick D. Roberts