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The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

This paper develops the first question answering dataset (DrugEHRQA) containing question-answer pairs from both structured tables and unstructured notes from a publicly available Electronic Health Record (EHR). EHRs contain patient records,…

Artificial Intelligence · Computer Science 2022-05-04 Jayetri Bardhan , Anthony Colas , Kirk Roberts , Daisy Zhe Wang

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

The growing adoption of electronic health record (EHR) systems has provided unprecedented opportunities for predictive modeling to guide clinical decision making. Structured EHRs contain longitudinal observations of patients across hospital…

Machine Learning · Computer Science 2026-03-12 Deyi Li , Zijun Yao , Qi Xu , Muxuan Liang , Lingyao Li , Zijian Xu , Mei Liu

Electronic health record (EHR) data is collected by individual institutions and often stored across locations in silos. Getting access to these data is difficult and slow due to security, privacy, regulatory, and operational issues. We…

Computers and Society · Computer Science 2018-12-04 Dianbo Liu , Timothy Miller , Raheel Sayeed , Kenneth D. Mandl

Federated Learning (FL) allows multiple privacy-sensitive applications to leverage their dataset for a global model construction without any disclosure of the information. One of those domains is healthcare, where groups of silos…

Machine Learning · Computer Science 2024-09-06 Usevalad Milasheuski , Luca Barbieri , Bernardo Camajori Tedeschini , Monica Nicoli , Stefano Savazzi

Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…

Machine Learning · Computer Science 2024-06-13 Ahmad Wisnu Mulyadi , Heung-Il Suk

This study addresses a critical gap in the healthcare system by developing a clinically meaningful, practical, and explainable disease surveillance system for multiple chronic diseases, utilizing routine EHR data from multiple U.S.…

Machine Learning · Computer Science 2025-01-28 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Ahmad Abdullah , Ibrahim Hashmat , Muddassar Farooq

This paper introduces a Blockchain-Integrated Explainable AI Framework (BXHF) for healthcare systems to tackle two essential challenges confronting health information networks: safe data exchange and comprehensible AI-driven clinical…

Cryptography and Security · Computer Science 2025-09-19 Md Talha Mohsin

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

In this paper, we propose a heterogeneous federated learning (HFL) system for sparse time series prediction in healthcare, which is a decentralized federated learning algorithm with heterogeneous transfers. We design dense and sparse…

Machine Learning · Computer Science 2025-01-22 Jia-Hao Syu , Jerry Chun-Wei Lin

In recent years, increasingly augmentation of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig…

Machine Learning · Computer Science 2019-05-09 Xi Sheryl Zhang , Fengyi Tang , Hiroko Dodge , Jiayu Zhou , Fei Wang

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Federated learning (FL), aimed at leveraging vast distributed datasets, confronts a crucial challenge: the heterogeneity of data across different silos. While previous studies have explored discrete representations to enhance model…

Machine Learning · Computer Science 2025-06-06 Tianyi Zhang , Yu Cao , Dianbo Liu

Existing Clinical Decision Support Systems (CDSSs) largely depend on the availability of structured patient data and Electronic Health Records (EHRs) to aid caregivers. However, in case of hospitals in developing countries, structured…

Computation and Language · Computer Science 2019-11-27 Gokul S Krishnan , Sowmya Kamath S

The adoption of digital systems in healthcare has resulted in the accumulation of vast electronic health records (EHRs), offering valuable data for machine learning methods to predict patient health outcomes. However, single-visit records…

Machine Learning · Computer Science 2024-11-19 Eric Yang , Pengfei Hu , Xiaoxue Han , Yue Ning

Concept bottleneck models are interpretable predictive models that are often used in domains where model trust is a key priority, such as healthcare. They identify a small number of human-interpretable concepts in the data, which they then…

Machine Learning · Computer Science 2024-12-25 Katrina Brown , Marton Havasi , Finale Doshi-Velez

Deep learning models for clinical event prediction on electronic health records (EHR) often suffer performance degradation when deployed under different data distributions. While domain adaptation (DA) methods can mitigate such shifts, its…

Machine Learning · Computer Science 2026-02-16 Pengfei Hu , Chang Lu , Feifan Liu , Yue Ning