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Nonparametric and semiparametric methods are commonly used in survival analysis to mitigate the bias due to model misspecification. However, such methods often cannot estimate upper-tail survival quantiles when a sizable proportion of the…

Methodology · Statistics 2019-07-19 Yifan Wang , Tian You , Martin Lysy

This paper presents a new algorithm, Evolutionary eXploration of Augmenting Memory Models (EXAMM), which is capable of evolving recurrent neural networks (RNNs) using a wide variety of memory structures, such as Delta-RNN, GRU, LSTM, MGU…

Neural and Evolutionary Computing · Computer Science 2019-02-12 Alexander Ororbia , Ahmed Ahmed Elsaid , Travis Desell

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

Applications · Statistics 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Analyses of time to event datasets have been invariably based on the Cox proportional hazards model (PHM). Reformulations of the PHM as a Poisson Generalized Additive Model (GAM) or as a Generalized Linear Mixed Model (GLMM) have been…

Methodology · Statistics 2025-03-17 Christos Argyropoulos , Hamza Mir , Maria-Eleni Roumelioti , Pablo Garcia

Accurate prediction of time-to-event outcomes is critical for clinical decision-making, treatment planning, and resource allocation in modern healthcare. While classical survival models such as Cox remain widely adopted in standard…

Machine Learning · Computer Science 2026-02-03 Marina Mastroleo , Alberto Archetti , Federico Mastroleo , Matteo Matteucci

This study introduces a novel generalized additive mixed model (GAMM) for mortality modelling, utilizing the mortality covariate $k_t$ as proposed by Dastranj-Kolar. Our findings indicate that the GAMM effectively addresses this…

Applications · Statistics 2025-11-18 Reza Dastranj , Martin Kolar

Flexible continuous-time survival modeling is critical for capturing complex time-varying hazard dynamics in high-dimensional data; however, training such models remains challenging due to the intractable integral required for likelihood…

Machine Learning · Statistics 2026-05-18 Chaeyeon Lee , Sehwan Kim , Hyungrok Do

When re-structuring patient cohorts into so-called population graphs, initially independent data points can be incorporated into one interconnected graph structure. This population graph can then be used for medical downstream tasks using…

Social and Information Networks · Computer Science 2023-09-20 Tamara T. Mueller , Sophie Starck , Leonhard F. Feiner , Kyriaki-Margarita Bintsi , Daniel Rueckert , Georgios Kaissis

Deep learning excels in the analysis of unstructured data and recent advancements allow to extend these techniques to survival analysis. In the context of clinical radiology, this enables, e.g., to relate unstructured volumetric images to a…

Machine Learning · Computer Science 2021-11-04 Tobias Weber , Michael Ingrisch , Matthias Fabritius , Bernd Bischl , David Rügamer

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

Machine Learning · Computer Science 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

Machine Learning · Computer Science 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia

Wide heterogeneity exists in cancer patients' survival, ranging from a few months to several decades. To accurately predict clinical outcomes, it is vital to build an accurate predictive model that relates patients' molecular profiles with…

Machine Learning · Statistics 2023-10-12 Yaohua Rong , Sihai Dave Zhao , Xia Zheng , Yi Li

Semi-parametric survival analysis methods like the Cox Proportional Hazards (CPH) regression (Cox, 1972) are a popular approach for survival analysis. These methods involve fitting of the log-proportional hazard as a function of the…

Machine Learning · Computer Science 2019-05-16 Chirag Nagpal , Rohan Sangave , Amit Chahar , Parth Shah , Artur Dubrawski , Bhiksha Raj

Neural architecture search has attracted wide attentions in both academia and industry. To accelerate it, researchers proposed weight-sharing methods which first train a super-network to reuse computation among different operators, from…

Machine Learning · Computer Science 2020-12-16 Xin Chen , Lingxi Xie , Jun Wu , Longhui Wei , Yuhui Xu , Qi Tian

Deep neural networks (DNNs) are one of the most highlighted methods in machine learning. However, as DNNs are black-box models, they lack explanatory power for their predictions. Recently, neural additive models (NAMs) have been proposed to…

Machine Learning · Computer Science 2022-05-23 Wonkeun Jo , Dongil Kim

We use a Quantum Extreme Learning Machine for characterizing and estimating parameters of quantum dynamics generated by a tunable collision model. The input to the learning protocol consists of quantum states produced by successive system…

Quantum Physics · Physics 2026-03-19 Hajar Assil , Abderrahim El Allati , Gian Luca Giorgi

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

There is currently great interest in applying neural networks to prediction tasks in medicine. It is important for predictive models to be able to use survival data, where each patient has a known follow-up time and event/censoring…

Machine Learning · Statistics 2020-02-12 Michael F. Gensheimer , Balasubramanian Narasimhan

Accurate and transparent prediction of cancer survival times on the level of individual patients can inform and improve patient care and treatment practices. In this paper, we design a model that concurrently learns to accurately predict…

Machine Learning · Computer Science 2018-01-31 Maruan Al-Shedivat , Avinava Dubey , Eric P. Xing

Evolutionary computation (EC)-based neural architecture search (NAS) has achieved remarkable performance in the automatic design of neural architectures. However, the high computational cost associated with evaluating searched architectures…

Neural and Evolutionary Computing · Computer Science 2025-05-01 Yangyang Li , Guanlong Liu , Ronghua Shang , Licheng Jiao