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Electronic Health Records (EHRs) are pivotal in clinical practices, yet their retrieval remains a challenge mainly due to semantic gap issues. Recent advancements in dense retrieval offer promising solutions but existing models, both…

Information Retrieval · Computer Science 2025-07-25 Zhengyun Zhao , Huaiyuan Ying , Yue Zhong , Sheng Yu

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing data in certain clinical variables is not at random but depends…

Machine Learning · Computer Science 2024-06-17 Hojjat Karami , David Atienza , Anisoara Ionescu

The diversity in disease profiles and therapeutic approaches between hospitals and health professionals underscores the need for patient-centric personalized strategies in healthcare. Alongside this, similarities in disease progression…

Machine Learning · Computer Science 2025-05-23 Navid Seidi , Satyaki Roy , Sajal K. Das , Ardhendu Tripathy

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

The identification of phenotypes within complex diseases or syndromes is a fundamental component of precision medicine, which aims to adapt healthcare to individual patient characteristics. Postoperative delirium (POD) is a complex…

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

Machine Learning · Computer Science 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu

Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network…

Information Retrieval · Computer Science 2018-10-09 Xuan Wang , Yu Zhang , Xiang Ren , Yuhao Zhang , Marinka Zitnik , Jingbo Shang , Curtis Langlotz , Jiawei Han

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

Patient subtyping based on temporal observations can lead to significantly nuanced subtyping that acknowledges the dynamic characteristics of diseases. Existing methods for subtyping trajectories treat the evolution of clinical observations…

Machine Learning · Computer Science 2018-11-30 Nikhil Galagali , Minnan Xu-Wilson

Accurate extraction of Alzheimer's Disease and Related Dementias (ADRD) phenotypes from electronic health records (EHR) is critical for early-stage detection and disease staging. However, this information is usually embedded in unstructured…

Artificial Intelligence · Computer Science 2026-03-17 Mingchen Shao , Yuzhang Xie , Carl Yang , Jiaying Lu

Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

Making the most use of abundant information in electronic health records (EHR) is rapidly becoming an important topic in the medical domain. Recent work presented a promising framework that embeds entire features in raw EHR data regardless…

Machine Learning · Computer Science 2023-05-11 Eunbyeol Cho , Min Jae Lee , Kyunghoon Hur , Jiyoun Kim , Jinsung Yoon , Edward Choi

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

Electronic health records (EHRs) contain important longitudinal information on individuals who have received medical care. Traditionally, EHRs have been used to support a wide range of administrative activities such as billing and clinical…

Databases · Computer Science 2024-11-18 Arian Aminoleslami , Geoffrey M. Anderson , Davide Chicco

In electronic health records (EHR) analysis, clustering patients according to patterns in their data is crucial for uncovering new subtypes of diseases. Existing medical literature often relies on classical hypothesis testing methods to…

Methodology · Statistics 2024-05-07 Zihan Zhu , Xin Gai , Anru R. Zhang

Electronic Health Record (EHR) tables pose unique challenges among which is the presence of hidden contextual dependencies between medical features with a high level of data dimensionality and sparsity. This study presents the first…

Computation and Language · Computer Science 2025-01-17 Jesus Lovon , Martin Mouysset , Jo Oleiwan , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Learning from electronic medical records (EMR) is challenging due to their relational nature and the uncertain dependence between a patient's past and future health status. Statistical relational learning is a natural fit for analyzing EMRs…

Machine Learning · Computer Science 2012-07-03 Jesse Davis , Vitor Santos Costa , Peggy Peissig , Michael Caldwell , Elizabeth Berg , David Page

Current machine learning has made great progress on computer vision and many other fields attributed to the large amount of high-quality training samples, while it does not work very well on genomic data analysis, since they are notoriously…

Machine Learning · Computer Science 2020-09-04 Ziyi Yang , Jun Shu , Yong Liang , Deyu Meng , Zongben Xu