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Inter-subject parcellation of functional Magnetic Resonance Imaging (fMRI) data based on a standard General Linear Model (GLM)and spectral clustering was recently proposed as a means to alleviate the issues associated with spatial…

Computer Vision and Pattern Recognition · Computer Science 2010-07-05 Yongnan Ji , Pierre-Yves Herve , Uwe Aickelin , Alain Pitiot

Social media is one of the most highly sought resources for analyzing characteristics of the language by its users. In particular, many researchers utilized various linguistic features of mental health problems from social media. However,…

Computation and Language · Computer Science 2023-06-06 Hoyun Song , Jisu Shin , Huije Lee , Jong C. Park

The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…

Machine Learning · Computer Science 2025-10-28 Rekha R Nair , Tina Babu , Alavikunhu Panthakkan , Hussain Al-Ahmad , Balamurugan Balusamy

Nowadays, many people worldwide suffer from brain disorders, and their health is in danger. So far, numerous methods have been proposed for the diagnosis of Schizophrenia (SZ) and attention deficit hyperactivity disorder (ADHD), among which…

Neuroimaging data, e.g. obtained from magnetic resonance imaging (MRI), is comparably homogeneous due to (1) the uniform structure of the brain and (2) additional efforts to spatially normalize the data to a standard template using linear…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Fabian Eitel , Jan Philipp Albrecht , Martin Weygandt , Friedemann Paul , Kerstin Ritter

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

The main idea of canonical correlation analysis (CCA) is to map different views onto a common latent space with maximum correlation. We propose a deep interpretable variational canonical correlation analysis (DICCA) for multi-view learning.…

Machine Learning · Statistics 2022-03-03 Lin Qiu , Lynn Lin , Vernon M. Chinchilli

Schizophrenia is a complex psychiatric disorder involving changes in thought patterns, perception, mood, and behavior. The diagnosis of schizophrenia is challenging and requires that patients show two or more positive symptoms for at least…

Machine Learning · Computer Science 2021-02-17 Maritza Tynes , Mahboobeh Parsapoor

Accurate and automated segmentation of intervertebral discs (IVDs) in medical images is crucial for assessing spine-related disorders, such as osteoporosis, vertebral fractures, or IVD herniation. We present HCA-Net, a novel contextual…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Afshin Bozorgpour , Bobby Azad , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

Deep Neural Networks (DNNs) are widely used for decision making in a myriad of critical applications, ranging from medical to societal and even judicial. Given the importance of these decisions, it is crucial for us to be able to interpret…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Teddy Koker , Fatemehsadat Mireshghallah , Tom Titcombe , Georgios Kaissis

The cross-modal synthesis between structural magnetic resonance imaging (sMRI) and functional network connectivity (FNC) is a relatively unexplored area in medical imaging, especially with respect to schizophrenia. This study employs…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yuda Bi , Anees Abrol , Jing Sui , Vince Calhoun

Unraveling how macroscopic cognitive phenotypes emerge from microscopic neuronal connectivity remains one of the core pursuits of neuroscience. To this end, researchers typically leverage multi-modal information from structural connectivity…

Artificial Intelligence · Computer Science 2026-02-03 Tianhao Huang , Guanghui Min , Zhenyu Lei , Aiying Zhang , Chen Chen

We consider exploratory methods for the discovery of cortical functional connectivity. Typically, data for the i-th subject (i=1...NS) is represented as an NVxNT matrix Xi, corresponding to brain activity sampled at NT moments in time from…

Methodology · Statistics 2011-03-17 Roberto D. Pascual-Marqui , Rolando J. Biscay-Lirio

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

In this work, we propose three explainable deep learning architectures to automatically detect patients with Alzheimer`s disease based on their language abilities. The architectures use: (1) only the part-of-speech features; (2) only…

Computation and Language · Computer Science 2021-01-11 Ning Wang , Mingxuan Chen , K. P. Subbalakshmi

Timely diagnosis of Intracranial hemorrhage (ICH) on Computed Tomography (CT) scans remains a clinical priority, yet the development of robust Artificial Intelligence (AI) solutions is still hindered by fragmented public data. To close this…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Kasra Davoodi , Mohammad Hoseyni , Javad Khoramdel , Reza Barati , Reihaneh Mortazavi , Amirhossein Nikoofard , Mahdi Aliyari-Shoorehdeli , Jaber Hatam Parikhan

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

Signal Processing · Electrical Eng. & Systems 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

Neurons and Cognition · Quantitative Biology 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…

Social and Information Networks · Computer Science 2020-06-11 Tommaso Lanciano , Francesco Bonchi , Aristides Gionis

The neural mechanisms supporting flexible relational inferences, especially in novel situations, are a major focus of current research. In the complementary learning systems framework, pattern separation in the hippocampus allows rapid…

Neurons and Cognition · Quantitative Biology 2021-05-20 Jacob Russin , Maryam Zolfaghar , Seongmin A. Park , Erie Boorman , Randall C. O'Reilly