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Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

Machine Learning · Computer Science 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen

Independent component analysis is commonly applied to functional magnetic resonance imaging (fMRI) data to extract independent components (ICs) representing functional brain networks. While ICA produces reliable group-level estimates,…

Methodology · Statistics 2020-06-05 Amanda F. Mejia , David Bolin , Yu Ryan Yue , Jiongran Wang , Brian S. Caffo , Mary Beth Nebel

Semantic segmentation of functional magnetic resonance imaging (fMRI) makes great sense for pathology diagnosis and decision system of medical robots. The multi-channel fMRI provides more information of the pathological features. But the…

Computer Vision and Pattern Recognition · Computer Science 2017-07-12 Lei Tai , Haoyang Ye , Qiong Ye , Ming Liu

Different brain imaging modalities offer unique insights into brain function and structure. Combining them enhances our understanding of neural mechanisms. Prior multimodal studies fusing functional MRI (fMRI) and structural MRI (sMRI) have…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Oktay Agcaoglu , Rogers F. Silva , Deniz Alacam , Sergey Plis , Tulay Adali , Vince Calhoun

In open data sets of functional magnetic resonance imaging (fMRI), the heterogeneity of the data is typically attributed to a combination of factors, including differences in scanning procedures, the presence of confounding effects, and…

Machine Learning · Computer Science 2026-04-17 Xin Wen , Shijie Guo , Wenbo Ning , Rui Cao , Yan Niu , Bin Wan , Peng Wei , Xiaobo Liu , Jie Xiang

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Nonlinear independent component analysis (ICA) provides an appealing framework for unsupervised feature learning, but the models proposed so far are not identifiable. Here, we first propose a new intuitive principle of unsupervised deep…

Machine Learning · Statistics 2016-05-23 Aapo Hyvarinen , Hiroshi Morioka

Finding overcomplete latent representations of data has applications in data analysis, signal processing, machine learning, theoretical neuroscience and many other fields. In an overcomplete representation, the number of latent features…

Machine Learning · Computer Science 2021-06-10 Jesse A. Livezey , Alejandro F. Bujan , Friedrich T. Sommer

Independent component analysis (ICA) is a popular tool for investigating brain organization in neuroscience research. In fMRI studies, an important goal is to study how brain networks are modulated by subjects' clinical and demographic…

Computation · Statistics 2020-04-08 Joshua Lukemire , Yikai Wang , Amit Verma , Ying Guo

Examining task-free functional connectivity (FC) in the human brain offers insights on how spontaneous integration and segregation of information relate to human cognition, and how this organization may be altered in different conditions,…

Recently, nonlinear ICA has surfaced as a popular alternative to the many heuristic models used in deep representation learning and disentanglement. An advantage of nonlinear ICA is that a sophisticated identifiability theory has been…

Machine Learning · Statistics 2023-11-29 Hermanni Hälvä , Jonathan So , Richard E. Turner , Aapo Hyvärinen

Independent Component Analysis (ICA) is a computational technique for revealing latent factors that underlie sets of measurements or signals. It has become a standard technique in functional neuroimaging. In functional neuroimaging, so…

We introduce a novel recurrent neural network (RNN) approach to account for temporal dynamics and dependencies in brain networks observed via functional magnetic resonance imaging (fMRI). Our approach directly parameterizes temporal…

Neural and Evolutionary Computing · Computer Science 2018-08-28 R Devon Hjelm , Eswar Damaraju , Kyunghyun Cho , Helmut Laufs , Sergey M. Plis , Vince Calhoun

We propose a novel denoising framework for task functional Magnetic Resonance Imaging (tfMRI) data to delineate the high-resolution spatial pattern of the brain functional connectivity via dictionary learning and sparse coding (DLSC). In…

Machine Learning · Computer Science 2017-07-24 Seongah Jeong , Xiang Li , Jiarui Yang , Quanzheng Li , Vahid Tarokh

Spatial Independent Component Analysis (ICA) decomposes the time by space functional MRI (fMRI) matrix into a set of 1-D basis time courses and their associated 3-D spatial maps that are optimized for mutual independence. When applied to…

Applications · Statistics 2015-05-30 Gautam V. Pendse , David Borsook , Lino Becerra

Recent studies have applied deep learning methods such as convolutional recurrent neural networks (CRNs) and Transformers to brain disease classification based on dynamic functional connectivity networks (dFCNs), such as Alzheimer's disease…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Zhixiang Zhang , Biao Jie , Zhengdong Wang , Jie Zhou , Yang Yang

Understanding how large-scale functional brain networks reorganize during cognitive decline remains a central challenge in neuroimaging. While recent self-supervised models have shown promise for learning representations from resting-state…

Machine Learning · Computer Science 2026-03-03 Karanpartap Singh , Adam Turnbull , Mohammad Abbasi , Kilian Pohl , Feng Vankee Lin , Ehsan Adeli

Brain functional connectivity (FC), the temporal synchrony between brain networks, is essential to understand the functional organization of the brain and to identify changes due to neurological disorders, development, treatment, and other…

Applications · Statistics 2025-06-18 Amanda Mejia , David Bolin , Daniel Spencer , Ani Eloyan

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

Applications · Statistics 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

Kernel and Multiple Kernel Canonical Correlation Analysis (CCA) are employed to classify schizophrenic and healthy patients based on their SNPs, DNA Methylation and fMRI data. Kernel and Multiple Kernel CCA are popular methods for finding…

Quantitative Methods · Quantitative Biology 2016-09-16 Owen Richfield , Md. Ashad Alam , Vince Calhoun , Yu-Ping Wang