Related papers: Surface Deformation During an Action Potential in …
Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…
The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…
Electroporation of biological cell membranes is a phenomena that occurs almost universally at a transmembrane potential of approximately 1000 mV. Theories of pore formation have been proposed based on electrocompression (Crowley 1972,…
Active matter with local polar or nematic order is subject to the well-known Simha-Ramaswamy instability. It is so far unclear how, despite this instability, biological tissues can undergo robust active anisotropic deformation during animal…
The paper considers rotations at different scales in granular materials: the rotations of individual particles, the rolling and rigid-rotation of particle pairs, the rotational interactions of a particle within its cluster of neighbors, and…
Coordinated movements of epithelia tissue are linked with active matter processes. We here consider the influence of curvature on the spatiotemporal arrangements and the shapes of the cells. The cells are represented by a multiphase field…
We coarse-grain a model of closely-packed ellipses that can vary their aspect ratio to derive continuum equations for materials comprising confluent deformable particles such as epithelial cell layers. We show that contractile nearest…
Recent theoretical studies show that nanoscale contact on dielectric substrates can induce flexoelectric polarization large enough to drive electron transfer. This has been supported by experimental evidence, indicating that contact…
Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…
Periodic structures are a type of metamaterial in which the physical properties depend not only on the details of the unit cell but also on how unit cells are arranged and interact with each other. In conventional engineering structures,…
The recent discovery of electro-active polymers has shown great promises in the field of soft robotics, and was logically followed by experimental, numerical and theoretical developments. Most of these studies were concerned with systems…
The propagation of an action potential is accompanied by mechanical and thermal effects. Several mathematical models explain the deformation of the unmyelinated axon wall. In this paper, the deformation of the myelinated axon wall is…
We present experimental and theoretical results for the surface topography of a plastically deformed metallic (aluminum) block. When a hard spherical body (here a steel-, silica glass- or silicon nitride ball) with a smooth surface is…
It is well known that lipid membranes respond to a threshold transmembrane electric field through a reversible mechanism called electroporation, where hydrophilic water pores form across the membrane, an effect widely used in biological…
We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…
Cells are modeled with spherical grains connected each other. Each cell can shrink and swell by transporting its fluid content to other connected neighbor while still maintaining its density at constant value. As a spherical part of a cell…
We investigate different mechanical effects which accompany the nerve pulse propagation by using mathematical modeling. The propagation process is composed by three connected phenomena: (i) the action potential (electrical signal) which is…
We present numerical analysis of the lateral movement of a deformable spherical capsule in a pulsatile channel flow, with a Newtonian fluid in almost inertialess condition and at a small confinement ratio $a_0/R = 0.4$, where $R$ and $a$…
Deployable structures, essential across various engineering applications ranging from umbrellas to satellites, are evolving to include soft, morphable designs where geometry drives transformation. However, a major challenge for soft…
The motion of a eukaryotic cell presents a variety of interesting and challenging problems from both a modeling and a computational perspective. The processes span many spatial scales (from molecular to tissue) as well as disparate time…