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Optical coherence tomography angiography (OCTA) has drawn numerous attentions in ophthalmology. However, its data acquisition is time-consuming, because it is based on temporal-decorrelation principle thus requires multiple repeated…

Medical Physics · Physics 2019-10-15 Jianlong Yang , Peng Liu , Lixin Duan , Yan Hu , Jiang Liu

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Optical Coherence Tomography Angiography (OCTA) has been increasingly used in the management of eye and systemic diseases in recent years. Manual or automatic analysis of blood vessel in 2D OCTA images (en face angiograms) is commonly used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-01 Shuai Yu , Jianyang Xie , Jinkui Hao , Yalin Zheng , Jiong Zhang , Yan Hu , Jiang Liu , Yitian Zhao

Optical coherence tomography (OCT) can perform non-invasive high-resolution three-dimensional (3D) imaging and has been widely used in biomedical fields, while it is inevitably affected by coherence speckle noise which degrades OCT imaging…

Optics · Physics 2025-06-30 Renxiong Wu , Fei Zheng , Meixuan Li , Shaoyan Huang , Xin Ge , Linbo Liu , Yong Liu , Guangming Ni

Machine learning methods play increasingly important roles in pre-procedural planning for complex surgeries and interventions. Very often, however, researchers find the historical records of emerging surgical techniques, such as the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-06 Jialei Chen , Yujia Xie , Kan Wang , Zih Huei Wang , Geet Lahoti , Chuck Zhang , Mani A Vannan , Ben Wang , Zhen Qian

Purpose: To assess the feasibility of deep learning-based high resolution synthetic CT generation from MRI scans of the lower arm for orthopedic applications. Methods: A conditional Generative Adversarial Network was trained to synthesize…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Frank Zijlstra , Koen Willemsen , Mateusz C. Florkow , Ralph J. B. Sakkers , Harrie H. Weinans , Bart C. H. van der Wal , Marijn van Stralen , Peter R. Seevinck

Last-generation GAN models allow to generate synthetic images which are visually indistinguishable from natural ones, raising the need to develop tools to distinguish fake and natural images thus contributing to preserve the trustworthiness…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Mauro Barni , Kassem Kallas , Ehsan Nowroozi , Benedetta Tondi

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

While multiplex immunofluorescence (mIF) imaging provides deep, spatially-resolved molecular data, integrating this information with the morphological standard of Hematoxylin & Eosin (H&E) can be very important for obtaining complementary…

Quantitative Methods · Quantitative Biology 2025-08-08 Jillur Rahman Saurav , Mohammad Sadegh Nasr , Jacob M. Luber

Virtual staining streamlines traditional staining procedures by digitally generating stained images from unstained or differently stained images. While conventional staining methods involve time-consuming chemical processes, virtual…

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Automated analysis of optical colonoscopy (OC) video frames (to assist endoscopists during OC) is challenging due to variations in color, lighting, texture, and specular reflections. Previous methods either remove some of these variations…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Shawn Mathew , Saad Nadeem , Arie Kaufman

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

The advent of Generative Adversarial Networks (GANs) has brought about completely novel ways of transforming and manipulating pixels in digital images. GAN based techniques such as Image-to-Image translations, DeepFakes, and other automated…

Computer Vision and Pattern Recognition · Computer Science 2019-10-04 Lakshmanan Nataraj , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , Arjuna Flenner , Jawadul H. Bappy , Amit K. Roy-Chowdhury , B. S. Manjunath

Ultrasound (US) imaging is widely used for anatomical structure inspection in clinical diagnosis. The training of new sonographers and deep learning based algorithms for US image analysis usually requires a large amount of data. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Jiamin Liang , Xin Yang , Yuhao Huang , Haoming Li , Shuangchi He , Xindi Hu , Zejian Chen , Wufeng Xue , Jun Cheng , Dong Ni

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Early detection and diagnosis of coronary artery disease (CAD) could save lives and reduce healthcare costs. The current clinical practice is to perform CAD diagnosis through analysing medical images from computed tomography coronary…

Pathological alterations in the human vascular system underlie many chronic diseases, such as atherosclerosis and aneurysms. However, manually analyzing diagnostic images of the vascular system, such as computed tomographic angiograms…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Alireza Bagheri Rajeoni , Breanna Pederson , Ali Firooz , Hamed Abdollahi , Andrew K. Smith , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar
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