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The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting…

Biomolecules · Quantitative Biology 2007-05-23 Richard A. Neher , Ulrich Gerland

Phase separation of two phase separating solutes in a common solvent can result in mesoscale (micron-sized) droplets with complex topologies of the domains of each solute within each droplet. Such topologies have been observed in-vitro in…

Soft Condensed Matter · Physics 2025-07-31 Amit Kumar , Gary H. Karpen , Samuel A. Safran

Found in all eukaryotic cells, linker histones H1 are known to bind to and rearrange nucleosomal linker DNA. In vitro, the fundamental nature of H1/DNA interactions has attracted wide interest among research communities - for biologists…

Biological Physics · Physics 2010-08-12 Rolf Dootz , Adriana Cristina Toma , Thomas Pfohl

In the present study, we have studied the electro-hydrodynamic of a physical system where a Newtonian dielectric liquid column or droplet suspended in another Newtonian dielectric liquid medium in presence of a simple shear flow. Taking…

Fluid Dynamics · Physics 2018-05-25 Somnath Santra , Shubhadeep Mandal , Suman Chakraborty

Using Brownian dynamics simulations, we study the migration of long charged chains in an electrophoretic microchannel device consisting of an array of microscopic entropic traps with alternating deep regions and narrow constrictions. Such a…

Biological Physics · Physics 2007-05-23 Martin Streek , Friederike Schmid , Thanh Tu Duong , Alexandra Ros

DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Steffen Both , Thomas Weiss , Na Liu

Orientational and positional ordering properties of liquid crystal monolayers are examined by means of Fundamental-Measure Density Functional Theory. Particles forming the monolayer are modeled as hard parallelepipeds of square section of…

Soft Condensed Matter · Physics 2015-06-19 Yuri Martinez-Raton , Szabolcs Varga y Enrique Velasco

By exploring a recent model [Palmeri, J., M. Manghi, and N. Destainville. 2007. Phys. Rev. Lett. 99:088103] where DNA bending elasticity, described by the wormlike chain model, is coupled to base-pair denaturation, we demonstrate that small…

Statistical Mechanics · Physics 2010-06-22 Nicolas Destainville , Manoel Manghi , John Palmeri

Phase separation is a fairly common physical phenomenon with examples including the formation of water droplets from humid air (fog, rain), the separation of a crystalline structure from an isotropic material such as a liquid or even the…

Probability · Mathematics 2007-05-23 Ágoston Pisztora

Active Brownian particles display self-propelled movement, which can be modelled as arising from a one-body force. Although their interparticle interactions are purely repulsive, for strong self propulsion the swimmers phase separate into…

Soft Condensed Matter · Physics 2021-03-25 Sophie Hermann , Daniel de las Heras , Matthias Schmidt

When processing dense emulsions, complex flows stretch and deform droplets to the point of breakup, changing the droplet size distribution and the mechanical properties of the final product. For steady homogeneous flows, a droplet's shape…

Fluid Dynamics · Physics 2023-05-29 Joseph Peterson , Ioannis Bagkeris , Vipin Michael

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target regulatory elements. To better…

Biomolecules · Quantitative Biology 2014-07-22 Cameron Mura , J. Andrew McCammon

Droplets are essential for spatially controlling biomolecules in cells. To work properly, cells need to control the emergence and morphology of droplets. On the one hand, driven chemical reactions can affect droplets profoundly. For…

Soft Condensed Matter · Physics 2024-03-14 Noah Ziethen , David Zwicker

Ionic liquids constrained at interfaces or restricted in subnanometric pores are increasingly employed in modern technologies, including energy applications. Understanding the details of their behavior in these conditions is therefore…

Materials Science · Physics 2018-09-25 Stefano Mossa

We study the phase ordering colloids suspended in a thermotropic nematic liquid crystal below the clearing point Tni and the resulting aggregated structure. Small (150nm) PMMA particles are dispersed in a classical liquid crystal matrix,…

Soft Condensed Matter · Physics 2007-05-23 V. J. Anderson , E. M. Terentjev , S. P. Meeker , J. Crain , W. C. K. Poon

The multiphase flow of droplets is widespread, both at the industrial and the microscale, for both biological and non-biological applications alike. But the ensemble interactions of such systems are inherently nonlinear and complex,…

Fluid Dynamics · Physics 2022-02-25 Wenyang Jing , Hee-Sun Han

The phase diagram of a water solution of DNA and oppositely charged spherical macroions is studied. DNA winds around spheres to form beads-on-a-string complexes resembling the chromatin 10 nm fiber. At small enough concentration of spheres…

Soft Condensed Matter · Physics 2009-11-07 Toan T. Nguyen , Boris I. Shklovskii

We demonstrate the realization of (laterally) optically bounded colloidal structures on a liquid-liquid interface of an emulsion droplet. We use DNA tethers to graft the particles to the droplet surface, effectively confining them to a…

Soft Condensed Matter · Physics 2017-03-27 Alessio Caciagli , Darshana Joshi , Jurij Kotar , Erika Eiser

The formation of condensates is now considered as a major organization principle of eukaryotic cells. Several studies have recently shown that the properties of these condensates are affected by enzymatic reactions. We propose here a simple…

Soft Condensed Matter · Physics 2024-11-19 Jacques Fries , Javier Diaz , Marie Jardat , Ignacio Pagonabarraga , Pierre Illien , Vincent Dahirel

The possibility of prescribing local interactions between nano- and microscopic components that direct them to assemble in a predictable fashion is a central goal of nanotechnology research. In this article we advance a new paradigm in…