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In structural optimization, both parameters and shape are relevant for the model performance. Yet, conventional optimization techniques usually consider either parameters or the shape separately. This work addresses this problem by…

Optimization and Control · Mathematics 2025-03-18 Michael Wiesheu , Theodor Komann , Melina Merkel , Sebastian Schöps , Stefan Ulbrich , Idoia Cortes Garcia

We develop a new computational approach for "focused" optimal Bayesian experimental design with nonlinear models, with the goal of maximizing expected information gain in targeted subsets of model parameters. Our approach considers…

Computation · Statistics 2019-03-28 Chi Feng , Youssef M. Marzouk

Critical aspects of computational imaging systems, such as experimental design and image priors, can be optimized through deep networks formed by the unrolled iterations of classical model-based reconstructions (termed physics-based…

Computer Vision and Pattern Recognition · Computer Science 2020-03-13 Michael Kellman , Kevin Zhang , Jon Tamir , Emrah Bostan , Michael Lustig , Laura Waller

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

Breast cancer histopathology image classification is critical for early detection and improved patient outcomes. 1 This study introduces a novel approach leveraging EfficientNetV2 models, to improve feature extraction and focus on relevant…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Naren Sengodan

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

Computer aided diagnosis (CAD) of Breast Cancer (BRCA) images has been an active area of research in recent years. The main goals of this research is to develop reliable automatic methods for detecting and diagnosing different types of BRCA…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Marco A. V. M. Grinet , Nuno M. Garcia , Ana I. R. Gouveia , Jose A. F. Moutinho , Abel J. P. Gomes

Electrical impedance tomography is an imaging modality for extracting information on the conductivity distribution inside a physical body from boundary measurements of current and voltage. In many practical applications, it is a priori…

Numerical Analysis · Mathematics 2014-06-06 Lauri Harhanen , Nuutti Hyvönen , Helle Majander , Stratos Staboulis

Computational models and simulations are not just appealing because of their intrinsic characteristics across spatiotemporal scales, scalability, and predictive power, but also because the set of problems in cancer biomedicine that can be…

Tissues and Organs · Quantitative Biology 2023-11-01 Nicolò Cogno , Cristian Axenie , Roman Bauer , Vasileios Vavourakis

Since Estimation of Distribution Algorithms (EDA) were proposed, many attempts have been made to improve EDAs' performance in the context of global optimization. So far, the studies or applications of multivariate probabilistic model based…

Neural and Evolutionary Computing · Computer Science 2011-11-10 Weishan Dong , Tianshi Chen , Peter Tino , Xin Yao

To accelerate MRI, the field of compressed sensing is traditionally concerned with optimizing the image quality after a partial undersampling of the measurable $\textit{k}$-space. In our work, we propose to change the focus from the quality…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Artem Razumov , Oleg Y. Rogov , Dmitry V. Dylov

Quantum sensing can enhance imaging performance by reducing measurement noise below the classical limit, thereby improving the signal-to-noise ratio (SNR) of acquired data. In conventional quantum imaging schemes, squeezing is applied…

Quantum Physics · Physics 2026-04-21 Haowei Shi , Visuttha Manthamkarn , Christopher M. Jones , Zheshen Zhang , Quntao Zhuang

Deep learning models in medical imaging face dual challenges: domain shift, where models perform poorly when deployed in settings different from their training environment, and class imbalance, where certain disease conditions are naturally…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Lei Li , Xinglin Zhang , Jun Liang , Tao Chen

Principal component analysis (PCA) is widely used for dimensionality reduction, with well-documented merits in various applications involving high-dimensional data, including computer vision, preference measurement, and bioinformatics. In…

Machine Learning · Statistics 2013-10-01 Gonzalo Mateos , Georgios B. Giannakis

Electropermeabilization is a clinical technique in cancer treatment to locally stimulate the cell metabolism. It is based on electrical fields that change the properties of the cell membrane. With that, cancer treatment can reach the cell…

Analysis of PDEs · Mathematics 2016-03-03 Habib Ammari , Thomas Widlak , Wenlong Zhang

We review a scalable two- and three-dimensional computer code for low-temperature plasma simulations in multi-material complex geometries. Our approach is based on embedded boundary (EB) finite volume discretizations of the minimal…

Computational Physics · Physics 2019-05-01 Robert Marskar

In medical image segmentation, limited external validity remains a critical obstacle when models are deployed across unseen datasets, an issue particularly pronounced in the ultrasound image domain. Existing solutions-such as domain…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Christian Schmidt , Heinrich Martin Overhoff

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…

Medical Physics · Physics 2021-08-11 Samuele Cavinato , Timo Felser , Marco Fusella , Marta Paiusco , Simone Montangero

Physics-driven artificial intelligence (PD-AI) reconstruction methods have emerged as the state-of-the-art for accelerating MRI scans, enabling higher spatial and temporal resolutions. However, the high resolution of these scans generates…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Yaşar Utku Alçalar , Yu Cao , Mehmet Akçakaya
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