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Living organisms interact with their surroundings in a closed-loop fashion, where sensory inputs dictate the initiation and termination of behaviours. Even simple animals are able to develop and execute complex plans, which has not yet been…

Robotics · Computer Science 2025-01-30 Giulia Lafratta , Bernd Porr , Christopher Chandler , Alice Miller

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…

Soft Condensed Matter · Physics 2025-09-04 James Clarke , Jake McGrath , Colin Johnson , José Alvarado

The sensory-triggered activity of a neuron is typically characterized in terms of a tuning curve, which describes the neuron's average response as a function of a parameter that characterizes a physical stimulus. What determines the shapes…

Neurons and Cognition · Quantitative Biology 2007-05-23 Emilio Salinas

Almost all organisms show some kind of time periodicity in their behavior. Especially in mammals the neurons of the suprachiasmatic nucleus form a biological clock regulating the activity-inactivity cycle of the animal. This clock is…

Adaptation and Self-Organizing Systems · Physics 2011-11-24 Domien G. M. Beersma , Henk W. Broer , Konstantinos Efstathiou , Kim A. Gargar , Igor Hoveijn

Collective motion in active matter is usually modelled through instantaneous local alignment, where each agent updates its heading from the current configuration of its neighbours. Many biological and engineered agents, however, possess…

Physics and Society · Physics 2026-05-11 Jyotiranjan Beuria

The activity of neurons is correlated, and this correlation affects how the brain processes information. We study the neural circuit mechanisms of correlations by analyzing a network model characterized by strong and heterogeneous…

Neurons and Cognition · Quantitative Biology 2012-12-03 Alberto Bernacchia , Xiao-Jing Wang

Humans and animals developed a sophisticated motor control apparatus and there is much evidence that it has a modular structure. The modularity offers a range of benefits, e.g. ability to learn dissociable motion styles without interference…

Robotics · Computer Science 2016-05-20 Kirill Makukhin

An internal model of the own body can be assumed a fundamental and evolutionary-early representation as it is present throughout the animal kingdom. Such functional models are, on the one hand, required in motor control, for example solving…

Robotics · Computer Science 2019-04-25 Malte Schilling

We propose a novel feedback controller for a class of uncertain higher-order nonlinear systems, subject to delays in both state measurement and control input signals. Building on the prescribed performance control framework, a…

Optimization and Control · Mathematics 2025-09-11 Thomas Berger , Lampros N. Bikas , Jan Hachmeister , George A. Rovithakis

Computational level explanations based on optimal feedback control with signal-dependent noise have been able to account for a vast array of phenomena in human sensorimotor behavior. However, commonly a cost function needs to be assumed for…

Machine Learning · Computer Science 2021-10-22 Matthias Schultheis , Dominik Straub , Constantin A. Rothkopf

Obtaining reliable feedback from the environment is a fundamental capability for intelligent agents to evaluate the correctness of their actions and to accumulate reusable knowledge. However, most existing approaches rely on predefined…

Artificial Intelligence · Computer Science 2026-01-09 Hong Su

The human brain receives complex inputs when performing cognitive tasks, which range from external inputs via the senses to internal inputs from other brain regions. However, the explicit inputs to the brain during a cognitive task remain…

Neurons and Cognition · Quantitative Biology 2024-04-26 Zhichao Liang , Yinuo Zhang , Jushen Wu , Quanying Liu

Animals must integrate sensory cues with their current behavioral context to generate a suitable response. How this integration occurs is poorly understood. Previously we developed high throughput methods to probe neural activity in…

Neurons and Cognition · Quantitative Biology 2023-09-25 Sandeep Kumar , Anuj K Sharma , Andrew Tran , Andrew M Leifer

Information processing in the brain requires integration of information over time. Such an integration can be achieved if signals are maintained in the network activity for the required period, as quantified by the intrinsic timescale.…

Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning. Inferring an agent's internal model is a crucial ingredient in social interactions (theory of mind),…

Machine Learning · Computer Science 2019-06-13 Zhengwei Wu , Paul Schrater , Xaq Pitkow

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

Flexible cognition requires the ability to rapidly detect systematic functions of variables and guide future behavior based on predictions. The model described here proposes a potential framework for patterns of neural activity to detect…

Neurons and Cognition · Quantitative Biology 2018-10-17 Michael E. Hasselmo

Controlling sensori-motor systems in higher animals or complex robots is a challenging combinatorial problem, because many sensory signals need to be simultaneously coordinated into a broad behavioural spectrum. To rapidly interact with the…

Disordered Systems and Neural Networks · Physics 2011-05-10 Silke Steingrube , Marc Timme , Florentin Woergoetter , Poramate Manoonpong

The brain's self-monitoring of activities, including internal activities -- a functionality that we refer to as awareness -- has been suggested as a key element of consciousness. Here we investigate whether the presence of an inner-eye-like…

Artificial Intelligence · Computer Science 2017-05-29 José F. Fontanari

We present a comprehensive, novel framework for understanding how the neocortex, including the thalamocortical loops through the deep layers, can support a temporal context representation in the service of predictive learning. Many have…

Neurons and Cognition · Quantitative Biology 2014-07-15 Randall C. O'Reilly , Dean Wyatte , John Rohrlich