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Spike timing dependent plasticity (STDP) is believed to play an important role in shaping the structure of neural circuits. Here we show that STDP generates effective interactions between synapses of different neurons, which were neglected…

Neurons and Cognition · Quantitative Biology 2016-08-25 Neta Ravid Tannenbaum , Yoram Burak

In eukaryotic cells, mitochondria form networks that range from highly fused interconnected structures to fragmented populations of individual organelles that undergo transient interactions. These structures can be described as temporal…

Biological Physics · Physics 2026-02-24 Keaton B. Holt , Camryn Zurita , Lizzy Teryoshin , Samantha C. Lewis , Elena F. Koslover

This article is devoted to the theoretical and numerical analysis of a network of excitatory and inhibitory neurons of Hodgkin-Huxley (HH) type, for which the topology is inspired by that of a single local layer of visual cortex V1. Our…

Neurons and Cognition · Quantitative Biology 2021-08-13 M. Maama , B. Ambrosio , M. A. Aziz-Alaoui , S. M. Mintchev

Recently spike timing dependent plasticity was observed in inhibitory synapse in the layer II of entorhinal cortex. The rule provides an interesting zero in the region of $\Delta t=t_{post}-t_{pre}=0$ and in addition the dynamic range of…

Neurons and Cognition · Quantitative Biology 2013-04-24 Sachin S Talathi

We study the effects of nonzero time delays in stochastic synchronization problems with linear couplings in complex networks. We consider two types of time delays: transmission delays between interacting nodes and local delays at each node…

Statistical Mechanics · Physics 2012-12-03 D. Hunt , B. K. Szymanski , G. Korniss

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Biological neural networks are characterized by their high degree of plasticity, a core property that enables the remarkable adaptability of natural organisms. Importantly, this ability affects both the synaptic strength and the topology of…

Neural and Evolutionary Computing · Computer Science 2024-06-17 Erwan Plantec , Joachin W. Pedersen , Milton L. Montero , Eleni Nisioti , Sebastian Risi

The mechanisms underlying how activity in the visual pathway may give rise through neural plasticity to many of the features observed experimentally in the early stages of visual processing was provided by Linkser in a seminal, three-paper…

Neurons and Cognition · Quantitative Biology 2020-11-30 Catherine E Davey , David B Grayden , Anthony N Burkitt

We analyze continuous Hopfield associative memories augmented by additional, rapid short-term associative synaptic plasticity. Through the cavity method, we determine the boundary between the retrieval and forgetting, or spin-glass phase,…

Neurons and Cognition · Quantitative Biology 2026-02-10 Martina Del Gaudio , Federico Ghimenti , Surya Ganguli

The fundamental `plasticity' of the nervous system (i.e high adaptability at different structural levels) is primarily based on Hebbian learning mechanisms that modify the synaptic connections. The modifications rely on neural activity and…

Adaptation and Self-Organizing Systems · Physics 2008-06-24 Gabor Szirtes , Zsolt Palotai , Andras Lorincz

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

Real-world networks in technology, engineering and biology often exhibit dynamics that cannot be adequately reproduced using network models given by smooth dynamical systems and a fixed network topology. Asynchronous networks give a…

Dynamical Systems · Mathematics 2017-02-07 Christian Bick , Michael Field

We investigate temporal coherence and spatial synchronization on small-world networks consisting of noisy Terman-Wang (TW) excitable neurons in dependence on two types of time-delayed coupling: $\{x_j(t-\tau)-x_i (t)\}$ and…

Disordered Systems and Neural Networks · Physics 2011-09-01 Hao Wu , Huijun Jiang , Zhonghuai Hou

Synaptic plasticity typically produces heavy-tailed distributions of synaptic strengths, consisting of a few strong connections among many weaker ones. Meanwhile, structural plasticity relies on distinct signaling cascades to reshape…

Neurons and Cognition · Quantitative Biology 2026-01-06 Jia Li , Cees van Leeuwen , Roman Bauer , Ilias Rentzeperis

Delayed interactions are a common property of coupled natural systems and therefore arise in a variety of different applications. For instance, signals in neural or laser networks propagate at finite speed giving rise to delayed…

Dynamical Systems · Mathematics 2015-06-12 Leonhard Lücken , Jan Philipp Pade , Kolja Knauer , Serhiy Yanchuk

Brains can process sensory information from different modalities at astonishing speed; this is surprising as the integration of inputs through the membrane of each individual neuron already causes a delayed response. Neuronal recordings…

Neurons and Cognition · Quantitative Biology 2024-08-20 Simon Brandt , Mihai Alexandru Petrovici , Walter Senn , Katharina Anna Wilmes , Federico Benitez

We develop a framework for collective frequency selection and attractor formation by means of delay plasticity. Specifically, we consider adaptive axonal delays (AADs), motivated by activity-dependent myelination in the brain which…

Adaptation and Self-Organizing Systems · Physics 2026-05-25 Stefan Ruschel , Emanuil Hristov , Hil G. E. Meijer , Stephen Coombes , Rachel Nicks

To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing on different cognitive systems. How does the brain's network of anatomical connections help facilitate…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Shi Gu , John D. Medaglia , Fabio Pasqualetti , Danielle S. Bassett

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

For energy-efficient computation in specialized neuromorphic hardware, we present spiking neural coding, an instantiation of a family of artificial neural models grounded in the theory of predictive coding. This model, the first of its…

Neural and Evolutionary Computing · Computer Science 2022-08-09 Alexander Ororbia