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Related papers: Information-Theoretic Foundations of DNA Data Stor…

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To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

Data storage in DNA is developing as a possible solution for archival digital data. Recently, to further increase the potential capacity of DNA-based data storage systems, the combinatorial composite DNA synthesis method was suggested. This…

Information Theory · Computer Science 2024-05-28 Omer Sabary , Inbal Preuss , Ryan Gabrys , Zohar Yakhini , Leon Anavy , Eitan Yaakobi

DNA has been discussed as a potential medium for data storage. Potentially it could be denser, could consume less energy, and could be more durable than conventional storage media such as hard drives, solid-state storage, and optical media.…

Emerging Technologies · Computer Science 2023-07-04 Arnav Solanki , Zak Griffin , Purab Ranjan Sutradhar , Amlan Ganguly , Marc D. Riedel

This paper studies two problems that are motivated by the novel recent approach of composite DNA that takes advantage of the DNA synthesis property which generates a huge number of copies for every synthesized strand. Under this paradigm,…

Information Theory · Computer Science 2025-05-15 Tomer Cohen , Eitan Yaakobi

In the current world due to the huge demand for storage, DNA-based storage solution sounds quite promising because of their longevity, low power consumption, and high capacity. However in real life storing data in the form of DNA is quite…

Information Theory · Computer Science 2024-04-09 Sanket Doshi , Mihir Gohel , Manish K. Gupta

Synthesis of DNA molecules offers unprecedented advances in storage technology. Yet, the microscopic world in which these molecules reside induces error patterns that are fundamentally different from their digital counterparts. Hence, to…

Information Theory · Computer Science 2017-08-08 Netanel Raviv , Moshe Schwartz , Eitan Yaakobi

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

Soft Condensed Matter · Physics 2008-05-02 Nicholas A. Licata

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect…

Information Theory · Computer Science 2025-11-25 Yu-Ting Lin , Hsin-Po Wang , Venkatesan Guruswami

The efficient storage of digital data is becoming very challenging over the years due to the exponential increase in the generation of data which can't compete with the existing storage resources. Furthermore, the infrequently accessed data…

Emerging Technologies · Computer Science 2021-03-18 Melpomeni Dimopoulou , Eva Gil San Antonio , Marc Antonini

Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, studied in arXiv:1203.6233, is what read length and coverage depth…

Information Theory · Computer Science 2022-02-09 Aditya Narayan Ravi , Alireza Vahid , Ilan Shomorony

The formation of DNA loops by proteins and protein complexes that bind at distal DNA sites plays a central role in many cellular processes, such as transcription, recombination, and replication. Here we review the basic thermodynamic…

Molecular Networks · Quantitative Biology 2007-05-23 Jose M. G. Vilar , Leonor Saiz

Information theory and the framework of information dynamics have been used to provide tools to characterise complex systems. In particular, we are interested in quantifying information storage, information modification and information…

Information Theory · Computer Science 2013-03-25 Oliver Obst , Joschka Boedecker , Benedikt Schmidt , Minoru Asada

This article proposes a blockchain-based file storage system that utilizes DNA encryption for enhanced security. The system utilizes blockchain technology to provide decentralized and tamper-proof file storage, while DNA encryption is…

Cryptography and Security · Computer Science 2023-10-12 Onur Yıldırım

We propose a novel and flexible DNA-storage architecture, which divides the storage space into fixed-size units (blocks) that can be independently and efficiently accessed at random for both read and write operations, and further allows…

Emerging Technologies · Computer Science 2023-10-02 Puru Sharma , Cheng-Kai Lim , Dehui Lin , Yash Pote , Djordje Jevdjic

In this paper, we propose the Neural Knowledge DNA, a framework that tailors the ideas underlying the success of neural networks to the scope of knowledge representation. Knowledge representation is a fundamental field that dedicate to…

Artificial Intelligence · Computer Science 2016-03-01 Haoxi Zhang , Cesar Sanin , Edward Szczerbicki

DNA-based data storage systems face practical challenges due to the high cost of DNA synthesis. A strategy to address the problem entails encoding data via topological modifications of the DNA sugar-phosphate backbone. The DNA Punchcards…

Emerging Technologies · Computer Science 2025-05-07 Jin Sima , Chao Pan , S. Kasra Tabatabaei , Alvaro G. Hernandez , Charles M. Schroeder , Olgica Milenkovic

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

Through in-depth thinking and reasoning about the conditions required for cells to maintain unchanged material distribution, it is concluded that life metabolic reactions require high information content. However, the self-replication of a…

Biological Physics · Physics 2024-08-27 Cheng Bi