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We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

Medical Physics · Physics 2025-10-22 Haotian Feng , Ke Sheng

In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and progression-free survival. In a cohort of 132 patients,…

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

This paper presents an overview of the second edition of the HEad and neCK TumOR (HECKTOR) challenge, organized as a satellite event of the 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI)…

Objective Neoadjuvant chemotherapy (NACT) is one kind of treatment for advanced stage ovarian cancer patients. However, due to the nature of tumor heterogeneity, the clinical outcomes to NACT vary significantly among different subgroups.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Ke Zhang , Neman Abdoli , Patrik Gilley , Youkabed Sadri , Xuxin Chen , Theresa C. Thai , Lauren Dockery , Kathleen Moore , Robert S. Mannel , Yuchen Qiu

Patients with metastatic breast cancer (mBC) undergo continuous medical imaging during treatment, making accurate lesion detection and monitoring over time critical for clinical decisions. Predicting drug response from post-treatment data…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Subrata Mukherjee

Neurofibromatosis Type 1 is a genetic disorder characterized by the development of neurofibromas (NFs), which exhibit significant variability in size, morphology, and anatomical location. Accurate and automated segmentation of these tumors…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Georgii Kolokolnikov , Marie-Lena Schmalhofer , Lennart Well , Said Farschtschi , Victor-Felix Mautner , Inka Ristow , Rene Werner

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer in which the tumor-vascular involvement greatly affects the resectability and, thus, overall survival of patients. However, current prognostic prediction methods fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Hexin Dong , Jiawen Yao , Yuxing Tang , Mingze Yuan , Yingda Xia , Jian Zhou , Hong Lu , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Yu Shi , Ling Zhang

Non-invasive colorectal cancer (CRC) screening represents a key opportunity to improve colonoscopy participation rates and reduce CRC mortality. This study explores the potential of the gut-liver axis for predicting colorectal neoplasia…

Early detection of cancer can help improve patient prognosis by early intervention. Head and neck cancer is diagnosed in specialist centres after a surgical biopsy, however, there is a potential for these to be missed leading to delayed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-08 Abdullah Alsalemi , Anza Shakeel , Mollie Clark , Syed Ali Khurram , Shan E Ahmed Raza

Prostate cancer is the most diagnosed form of cancer in Canadian men, and is the third leading cause of cancer death. Despite these statistics, prognosis is relatively good with a sufficiently early diagnosis, making fast and reliable…

Computer Vision and Pattern Recognition · Computer Science 2015-10-21 Audrey G. Chung , Mohammad Javad Shafiee , Devinder Kumar , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Brain tumor segmentation is a critical task for tumor volumetric analyses and AI algorithms. However, it is a time-consuming process and requires neuroradiology expertise. While there has been extensive research focused on optimizing brain…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Partoo Vafaeikia , Matthias W. Wagner , Uri Tabori , Birgit B. Ertl-Wagner , Farzad Khalvati

Brain tumor is one of the leading causes of cancer death. The high-grade brain tumors are easier to recurrent even after standard treatment. Therefore, developing a method to predict brain tumor recurrence location plays an important role…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Tongxue Zhou , Alexandra Noeuveglise , Romain Modzelewski , Fethi Ghazouani , Sébastien Thureau , Maxime Fontanilles , Su Ruan

Radiomics and deep learning both offer powerful tools for quantitative medical imaging, but most existing fusion approaches only leverage global radiomic features and overlook the complementary value of spatially resolved radiomic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Zengtian Deng , Yimeng He , Yu Shi , Lixia Wang , Touseef Ahmad Qureshi , Xiuzhen Huang , Debiao Li

In this paper we propose a method for predicting the status of MGMT promoter methylation in high-grade gliomas. From the available MR images, we segment the tumor using deep convolutional neural networks and extract both radiomic features…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Koen Van Leemput

Despite the unprecedented performance of deep neural networks (DNNs) in computer vision, their practical application in the diagnosis and prognosis of cancer using medical imaging has been limited. One of the critical challenges for…

Machine Learning · Computer Science 2023-04-27 Lennart Brocki , Neo Christopher Chung

Automated segmentation proves to be a valuable tool in precisely detecting tumors within medical images. The accurate identification and segmentation of tumor types hold paramount importance in diagnosing, monitoring, and treating highly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Fadillah Maani , Anees Ur Rehman Hashmi , Mariam Aljuboory , Numan Saeed , Ikboljon Sobirov , Mohammad Yaqub

Distant metastases (DM) refer to the dissemination of tumors, usually, beyond the organ where the tumor originated. They are the leading cause of death in patients with soft-tissue sarcomas (STSs). Positron emission tomography-computed…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Yige Peng , Lei Bi , Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

Segmenting brain tumors in multi-parametric magnetic resonance imaging enables performing quantitative analysis in support of clinical trials and personalized patient care. This analysis provides the potential to impact clinical…

Stereotactic radiotherapy (SRT) is one of the most important treatment for patients with brain metastases (BM). Conventionally, following SRT patients are monitored by serial imaging and receive salvage treatments in case of significant…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Philipp Sommer , Yixing Huang , Christoph Bert , Andreas Maier , Manuel Schmidt , Arnd Dörfler , Rainer Fietkau , Florian Putz