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Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Radiomics is an exciting new area of texture research for extracting quantitative and morphological characteristics of pathological tissue. However, to date, only single images have been used for texture analysis. We have extended radiomic…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Vishwa S. Parekh , John Laterra , Chetan Bettegowda , Alex E. Bocchieri , Jay J. Pillai , Michael A. Jacobs

Head and neck cancers are the fifth most common cancer worldwide, and recently, analysis of Positron Emission Tomography (PET) and Computed Tomography (CT) images has been proposed to identify patients with a prognosis. Even though the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Vajira Thambawita , Andrea M. Storås , Steven A. Hicks , Pål Halvorsen , Michael A. Riegler

Objectives: High-grade serous ovarian carcinoma (HGSOC) is typically diagnosed at an advanced stage with extensive peritoneal metastases, making treatment challenging. Neoadjuvant chemotherapy (NACT) is often used to reduce tumor burden…

Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Ikboljon Sobirov

Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

Lung cancer is the leading cause for cancer related deaths. As such, there is an urgent need for a streamlined process that can allow radiologists to provide diagnosis with greater efficiency and accuracy. A powerful tool to do this is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-29 Devinder Kumar , Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Background: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along…

Quantitative Methods · Quantitative Biology 2025-03-04 Khashayar Namdar , Matthias W. Wagner , Birgit B. Ertl-Wagner , Farzad Khalvati

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yaxi Chen , Zi Ye , Shaheer U. Saeed , Oliver Yu , Simin Ni , Jie Huang , Yipeng Hu

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Inye Na , Nejung Rue , Jiwon Chung , Hyunjin Park

Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities caused by high-dose exposure to critical structures remain a…

Accurate prognosis of a tumor can help doctors provide a proper course of treatment and, therefore, save the lives of many. Traditional machine learning algorithms have been eminently useful in crafting prognostic models in the last few…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Numan Saeed , Roba Al Majzoub , Ikboljon Sobirov , Mohammad Yaqub

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Daniil Tikhonov , Matheus Scatolin , Mohor Banerjee , Qiankun Ji , Ahmed Jaheen , Mostafa Salem , Abdelrahman Elsayed , Hu Wang , Sarim Hashmi , Mohammad Yaqub

A reliable locoregional recurrence (LRR) prediction model is important for the personalized management of head and neck cancers (HNC) patients. This work aims to develop a delta-radiomics feature-based multi-classifier, multi-objective, and…

Medical Physics · Physics 2023-05-10 Kai Wang , Michael Dohopolski , Qiongwen Zhang , David Sher , Jing Wang

Breast cancer is the most prevalent cancer among women and predicting pathologic complete response (pCR) after anti-cancer treatment is crucial for patient prognosis and treatment customization. Deep learning has shown promise in medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park