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The recent improvements in cryo-electron microscopy (cryo-EM) in the past few years are now allowing to observe molecular complexes at atomic resolution. As a consequence, numerous structures derived from cryo-EM are now available in the…

Biomolecules · Quantitative Biology 2020-05-04 Mikael Trellet , Gydo van Zundert , Alexandre M. J. J. Bonvin

Although a superconductor has no DC losses, a superconducting system does have significant losses, especially when it comes to power supply. Here, we study two different power supply systems. The first, a conventional one, consists of a…

The relentless pursuit of miniaturization and performance enhancement in electronic devices has led to a fundamental challenge in the field of circuit design and simulation: how to accurately account for the inherent stochastic nature of…

Machine Learning · Computer Science 2023-11-13 Jack Hutchins , Shamiul Alam , Dana S. Rampini , Bakhrom G. Oripov , Adam N. McCaughan , Ahmedullah Aziz

Scalable quantum photonics relies on interfacing many optical components under mutually compatible operating conditions. To that end, we demonstrate that spontaneous parametric down-conversion (SPDC) in nonlinear waveguides, a standard…

Quantum computers are nearing the thousand qubit mark, with the current focus on scaling to improve computational performance. As quantum processors grow in complexity, new challenges arise such as the management of device variability and…

Ferroelectric-based capacitive crossbar arrays have been proposed for energy-efficient in-memory computing in the charge domain. They combat the challenges like sneak paths and high static power faced by resistive crossbar arrays but are…

Emerging Technologies · Computer Science 2025-10-30 Madhav Vadlamani , Dyutimoy Chakraborty , Jianwei Jia , Halid Mulaosmanovic , Stefan Duenkel , Sven Beyer , Suman Datta , Shimeng Yu

This work builds on the previous introduction [1] of a coupled experimental-computational system devised to fully characterize the thermal behavior of complex 3D submicron electronic devices. The new system replaces the laser-based surface…

Materials Science · Physics 2007-09-13 Peter E. Raad , Pavel L. Komarov , M. Burzo

In this paper, a simple algorithm for detailed system-level thermal noise analysis is developed, demonstrated, and verified. This method uses noise-wave theory and noise covariance matrices to cascade noise and scattering parameters of…

Instrumentation and Detectors · Physics 2022-09-12 Maurio B. Grando , Christian R. Boutan , Jihee Yang

Diversification of digital applications and workloads has driven the development of diverse datacenter architectures on ever-larger scales. These datacenters consist of complex IT, power, and cooling systems with interdependencies that…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Wedan Emmanuel Gnibga , Andrew A. Chien

Quantum computing, ultra-low-noise sensing, and high-energy physics experiments often rely on superconducting circuits or semiconductor qubits and devices operating at deep cryogenic temperatures (4K and below). Photonic integrated circuits…

The design and performance of a low-noise, modular cryogenic probe, applicable to a wide range of measurements over a broad range of working frequencies, temperatures, and magnetic fields is presented. The design of the probe facilitates…

Other Condensed Matter · Physics 2022-10-13 Erick Garcia , Calvin Bales , William Patterson , Alexander Zaslavsky , Vesna F. Mitrović

Large-scale superconducting quantum computers require massive numbers of high-performance cryogenic low-noise amplifiers (cryo-LNA) for qubit readout. Here we present a C-Band monolithic microwave integrated circuit (MMIC) cryo-LNA for this…

X-ray calorimetric sample platforms combining specific heat and synchrotron x-ray measurements provide a powerful means to investigate fundamental material properties. Calorimeter cell designs featuring a compact heater and thermometer…

Instrumentation and Detectors · Physics 2026-02-02 U. Patel , H. Zheng , J. L. McChesney , U. Welp , Z. Islam , A. Miceli

Temperature sensors with micro- and nanoscale spatial resolution have long been explored for their potential to investigate the details of physical systems at an unprecedented scale. In particular, the rapid miniaturization of transistor…

Computationally expensive temperature and power grid analyses are required during the design cycle to guide IC design. This paper employs encoder-decoder based generative (EDGe) networks to map these analyses to fast and accurate…

Hardware Architecture · Computer Science 2020-09-22 Vidya A. Chhabria , Vipul Ahuja , Ashwath Prabhu , Nikhil Patil , Palkesh Jain , Sachin S. Sapatnekar

Cryogenic test facilities are critical infrastructure for physics experiments in a variety of fields, perhaps most notably for particle detection with noble liquid detectors, low-temperature device development, and quantum information…

Quantum computing (QC) has already entered the industrial landscape and several multinational corporations have initiated their own research efforts. So far, many of these efforts have been focusing on superconducting qubits, whose…

Quantum Physics · Physics 2019-08-08 Farzan Jazaeri , Arnout Beckers , Armin Tajalli , Jean-Michel Sallese

The optimal design of power converters requires accurate knowledge of the dissipation elements of its system to achieve the desired performance and security requirements. Calorimetric methods have surpassed classical electrical methods for…

Systems and Control · Electrical Eng. & Systems 2023-11-06 Jose Miguel Sanz-Alcaine , Eduardo Sebastian , Francisco Jose Perez-Cebolla , Asier Arruti , Carlos Bernal-Ruiz , Iosu Aizpuru

The next generation of ultra-low-noise cryogenic detectors for space science applications require continued exploration of materials characteristics at low temperatures. The low noise and good energy sensitivity of current Transition Edge…

Mesoscale and Nanoscale Physics · Physics 2011-02-01 D. J. Goldie , D. M. Glowacka , K. Rostem† , S. Withington

This chapter gives an overview of the principles of low temperature refrigeration and the thermodynamics behind it. Basic cryogenic processes - Joule-Thomoson process, Brayton process as well as Claude process - are described and compared.…

Accelerator Physics · Physics 2015-01-30 A. Alekseev
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