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Designing flexible probabilistic models over tree topologies is important for developing efficient phylogenetic inference methods. To do that, previous works often leverage the similarity of tree topologies via hand-engineered heuristic…

Populations and Evolution · Quantitative Biology 2023-10-17 Tianyu Xie , Cheng Zhang

Tree ensembles are very popular machine learning models, known for their effectiveness in supervised classification and regression tasks. Their performance derives from aggregating predictions of multiple decision trees, which are renowned…

Optimization and Control · Mathematics 2025-01-14 Lorenzo Bonasera , Emilio Carrizosa

Diffusion models have revolutionized generative tasks through high-fidelity outputs, yet flow matching (FM) offers faster inference and empirical performance gains. However, current foundation FM models are computationally prohibitive for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Johannes Schusterbauer , Ming Gui , Frank Fundel , Björn Ommer

Program comprehension is a fundamental task in software development and maintenance processes. Software developers often need to understand a large amount of existing code before they can develop new features or fix bugs in existing…

Machine Learning · Computer Science 2019-10-29 Vinoj Jayasundara , Nghi Duy Quoc Bui , Lingxiao Jiang , David Lo

Probabilistic programming languages represent complex data with intermingled models in a few lines of code. Efficient inference algorithms in probabilistic programming languages make possible to build unified frameworks to compute…

Machine Learning · Statistics 2016-07-15 Anh Tong , Jaesik Choi

Phylogeny is the field of modelling the temporal discrete dynamics of speciation. Complex models can nowadays be studied using the Approximate Bayesian Computation approach which avoids likelihood calculations. The field's progression is…

Populations and Evolution · Quantitative Biology 2020-11-23 Krzysztof Bartoszek , Pietro Liò

Dataflow programming is a popular and convenient programming paradigm in systems modelling, optimisation, and machine learning. It has a number of advantages, for instance the lacks of control flow allows computation to be carried out in…

Programming Languages · Computer Science 2021-03-03 Steven W. T. Cheung , Dan R. Ghica , Koko Muroya

Differential evolution possesses a multitude of various strategies for generating new trial solutions. Unfortunately, the best strategy is not known in advance. Moreover, this strategy usually depends on the problem to be solved. This paper…

Neural and Evolutionary Computing · Computer Science 2013-07-04 Iztok Fister , Iztok Fister , Janez Brest

Motivation: Many inference tools use the Perfect Phylogeny Model (PPM) to learn trees from noisy variant allele frequency (VAF) data. Learning in this setting is hard, and existing tools use approximate or heuristic algorithms. An…

Quantitative Methods · Quantitative Biology 2019-08-26 Surjyendu Ray , Bei Jia , Sam Safavi , Tim van Opijnen , Ralph Isberg , Jason Rosch , José Bento

TensorFlow is a popular cloud computing framework that targets machine learning applications. It separates the specification of application logic (in a dataflow graph) from the execution of the logic. TensorFlow's native runtime executes…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-27 Sam Whitlock , James Larus , Edouard Bugnion

Estimating phylogenetic trees is an important problem in evolutionary biology, environmental policy and medicine. Although trees are estimated, their uncertainties are discarded by mathematicians working in tree space. Here we explicitly…

Methodology · Statistics 2017-10-16 Amy D. Willis , Rayna C. Bell

Speculative optimisation relies on the estimation of the probabilities that certain properties of the control flow are fulfilled. Concrete or estimated branch probabilities can be used for searching and constructing advantageous speculative…

Programming Languages · Computer Science 2013-07-18 Alessandra Di Pierro , Herbert Wiklicky

Sampling a target probability distribution with an unknown normalization constant is a fundamental challenge in computational science and engineering. Recent work shows that algorithms derived by considering gradient flows in the space of…

Machine Learning · Statistics 2024-03-12 Yifan Chen , Daniel Zhengyu Huang , Jiaoyang Huang , Sebastian Reich , Andrew M Stuart

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

Data Structures and Algorithms · Computer Science 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

Artificial intelligence has recently experienced remarkable advances, fueled by large models, vast datasets, accelerated hardware, and, last but not least, the transformative power of differentiable programming. This new programming…

Machine Learning · Computer Science 2025-06-25 Mathieu Blondel , Vincent Roulet

Predicting future states or actions of a given system remains a fundamental, yet unsolved challenge of intelligence, especially in the scope of complex and non-deterministic scenarios, such as modeling behavior of humans. Existing…

Machine Learning · Computer Science 2020-12-01 Maciej Zięba , Marcin Przewięźlikowski , Marek Śmieja , Jacek Tabor , Tomasz Trzcinski , Przemysław Spurek

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

Populations and Evolution · Quantitative Biology 2022-07-27 Brandon Legried , Sebastien Roch

Regression trees have emerged as a preeminent tool for solving real-world regression problems due to their ability to deal with nonlinearities, interaction effects and sharp discontinuities. In this article, we rather study regression trees…

Machine Learning · Statistics 2025-11-14 Nathan Wycoff

Distributed inference serves as a promising approach to enabling the inference of large language models (LLMs) at the network edge. It distributes the inference process to multiple devices to ensure that the LLMs can fit into the device…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-13 Xing Liu , Lizhuo Luo , Ming Tang , Chao Huang , Xu Chen

Towards a future where machine learning systems will integrate into every aspect of people's lives, researching methods to interpret such systems is necessary, instead of focusing exclusively on enhancing their performance. Enriching the…

Machine Learning · Computer Science 2021-12-21 Ioannis Mollas , Nick Bassiliades , Ioannis Vlahavas , Grigorios Tsoumakas
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