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Quantitative disease severity scoring in medical imaging is costly, time-consuming, and subject to inter-reader variability. At the same time, clinical archives contain far more longitudinal imaging data than expert-annotated severity…

Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Qianying Liu , Xiao Gu , Paul Henderson , Fani Deligianni

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Medical image interpretation using deep learning has shown promise but often requires extensive expert-annotated datasets. To reduce this annotation burden, we develop an Image-Graph Contrastive Learning framework that pairs chest X-rays…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Sameer Khanna , Daniel Michael , Marinka Zitnik , Pranav Rajpurkar

Lesion detection is a fundamental problem in the computer-aided diagnosis scheme for mammography. The advance of deep learning techniques have made a remarkable progress for this task, provided that the training data are large and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Zheren Li , Zhiming Cui , Sheng Wang , Yuji Qi , Xi Ouyang , Qitian Chen , Yuezhi Yang , Zhong Xue , Dinggang Shen , Jie-Zhi Cheng

Learning good representations involves capturing the diverse ways in which data samples relate. Contrastive loss - an objective matching related samples - underlies methods from self-supervised to multimodal learning. Contrastive losses,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Vlad Sobal , Mark Ibrahim , Randall Balestriero , Vivien Cabannes , Diane Bouchacourt , Pietro Astolfi , Kyunghyun Cho , Yann LeCun

Vast quantities of person-generated health data (wearables) are collected but the process of annotating to feed to machine learning models is impractical. This paper discusses ways in which self-supervised approaches that use contrastive…

Machine Learning · Computer Science 2021-11-16 Kevalee Shah , Dimitris Spathis , Chi Ian Tang , Cecilia Mascolo

Medical image labels are often organized by taxonomies (e.g., organ - tissue - subtype), yet standard self-supervised learning (SSL) ignores this structure. We present a hierarchy-preserving contrastive framework that makes the label tree a…

Quantitative Methods · Quantitative Biology 2025-11-07 Alif Elham Khan

Well-annotated medical datasets enable deep neural networks (DNNs) to gain strong power in extracting lesion-related features. Building such large and well-designed medical datasets is costly due to the need for high-level expertise. Model…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Yixiong Chen , Chunhui Zhang , Chris H. Q. Ding , Li Liu

Multi-label classification, which involves assigning multiple labels to a single input, has emerged as a key area in both research and industry due to its wide-ranging applications. Designing effective loss functions is crucial for…

Machine Learning · Computer Science 2025-01-06 Alexandre Audibert , Aurélien Gauffre , Massih-Reza Amini

Visual recognition is recently learned via either supervised learning on human-annotated image-label data or language-image contrastive learning with webly-crawled image-text pairs. While supervised learning may result in a more…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Jianwei Yang , Chunyuan Li , Pengchuan Zhang , Bin Xiao , Ce Liu , Lu Yuan , Jianfeng Gao

Contrastive learning methods in computer vision typically rely on augmented views of the same image or multimodal pretraining strategies that align paired modalities. However, these approaches often overlook semantic relationships between…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Marta Hasny , Maxime Di Folco , Keno Bressem , Julia Schnabel

Learning visual representations of medical images (e.g., X-rays) is core to medical image understanding but its progress has been held back by the scarcity of human annotations. Existing work commonly relies on fine-tuning weights…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Yuhao Zhang , Hang Jiang , Yasuhide Miura , Christopher D. Manning , Curtis P. Langlotz

Unsupervised learning has been a long-standing goal of machine learning and is especially important for medical image analysis, where the learning can compensate for the scarcity of labeled datasets. A promising subclass of unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ozan Ciga , Tony Xu , Anne L. Martel

Contrastive self-supervised learning has been successfully used in many domains, such as images, texts, graphs, etc., to learn features without requiring label information. In this paper, we propose a new local contrastive feature learning…

Machine Learning · Computer Science 2022-11-22 Zhabiz Gharibshah , Xingquan Zhu

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Huai Chen , Renzhen Wang , Xiuying Wang , Jieyu Li , Qu Fang , Hui Li , Jianhao Bai , Qing Peng , Deyu Meng , Lisheng Wang

Many contrastive representation learning methods learn a single global representation of an entire image. However, dense contrastive representation learning methods such as DenseCL (Wang et al., 2021) can learn better representations for…

Computer Vision and Pattern Recognition · Computer Science 2023-01-12 Berk Iskender , Zhenlin Xu , Simon Kornblith , En-Hung Chu , Maryam Khademi

Disease diagnosis from medical images via supervised learning is usually dependent on tedious, error-prone, and costly image labeling by medical experts. Alternatively, semi-supervised learning and self-supervised learning offer…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Attiano Purpura-Pontoniere , Demetri Terzopoulos , Adam Wang , Abdullah-Al-Zubaer Imran