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Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Pathologically altered iron levels, detected using iron-sensitive MRI techniques such as quantitative susceptibility mapping (QSM), are observed in neurological disorders such as multiple sclerosis (MS) and may play a crucial role in…

Motivation - The test-retest reliability of quantitative susceptibility mapping (QSM) is affected by parameters of the acquisition protocol such as the angulation of acquisition plane with respect to the B0 field direction and spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Shuai Huang , Thomas Denney , Deqiang Qiu

Quantitative susceptibility mapping (QSM) has gained broad interests in the field by extracting biological tissue properties, predominantly myelin, iron and calcium from magnetic resonance imaging (MRI) phase measurements in vivo. Thereby,…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Woojin Jung , Steffen Bollmann , Jongho Lee

This article provides recommendations for implementing quantitative susceptibility mapping (QSM) for clinical brain research. It is a consensus of the ISMRM Electro-Magnetic Tissue Properties Study Group. While QSM technical development…

Quantitative susceptibility mapping (QSM) aims to visualize the three dimensional susceptibility distribution by solving the field-to-source inverse problem using the phase data in magnetic resonance signal. However, the inverse problem is…

Numerical Analysis · Mathematics 2018-12-31 Chenglong Bao , Jae Kyu Choi , Bin Dong

Brain iron deposition, in particular deep gray matter nuclei, increases with advancing age. Hereditary Hemochromatosis (HH) is the most common inherited disorder of systemic iron excess in Europeans and recent studies claimed high brain…

Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates magnetic susceptibility of tissue from Larmor frequency offset measurements. The generation of QSM requires solving a challenging…

Medical Physics · Physics 2020-08-18 Juan Liu , Kevin M. Koch

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to estimate local tissue susceptibility, which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue. QSM requires addressing a…

Medical Physics · Physics 2019-06-03 Juan Liu , Kevin M. Koch

Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Yicheng Chen , Angela Jakary , Sivakami Avadiappan , Christopher P. Hess , Janine M. Lupo

Quantitative Susceptibility Mapping (QSM) is a technique for measuring magnetic susceptibility of tissues, aiding in the detection of pathologies like traumatic brain injury and multiple sclerosis by analyzing variations in substances such…

Quantitative Methods · Quantitative Biology 2025-06-05 Liad Doniza , Mitchel Lee , Tamar Blumenfeld Katzir , Moran Artzi , Dafna Ben Bashat , Dvir Radunsky , Karin Shmueli , Noam Ben-Eliezer

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing technique to extract the distribution of tissue susceptibilities, demonstrating significant potential in studying neurological diseases. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Min Li , Chen Chen , Zhuang Xiong , Ying Liu , Pengfei Rong , Shanshan Shan , Feng Liu , Hongfu Sun , Yang Gao

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…

Image and Video Processing · Electrical Eng. & Systems 2019-05-16 Hongjiang Wei , Steven Cao , Yuyao Zhang , Xiaojun Guan , Fuhua Yan , Kristen W. Yeom , Chunlei Liu

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing method that quantifies tissue magnetic susceptibility distributions. However, QSM acquisitions are relatively slow, even with parallel imaging. Incoherent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Yang Gao , Martijn Cloos , Feng Liu , Stuart Crozier , G. Bruce Pike , Hongfu Sun

Accurate estimation of microscopic magnetic field variations induced in biological tissue can be valuable for mapping tissue composition in health and disease. Here, we present an extension to Quantitative susceptibility mapping (QSM) to…

Quantitative susceptibility mapping (QSM) is a MRI technique that estimates tissue magnetic susceptibility. The generation of QSM requires solving a challenging ill-posed field-to-source inversion problem. Recently, several deep learning…

Medical Physics · Physics 2022-06-28 Juan Liu , Kevin Koch

Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Deep neural networks have demonstrated promising potential for the field of medical image reconstruction. In this work, an MRI reconstruction algorithm, which is referred to as quantitative susceptibility mapping (QSM), has been developed…

Image and Video Processing · Electrical Eng. & Systems 2018-06-18 Jaeyeon Yoon , Enhao Gong , Itthi Chatnuntawech , Berkin Bilgic , Jingu Lee , Woojin Jung , Jingyu Ko , Hosan Jung , Kawin Setsompop , Greg Zaharchuk , Eung Yeop Kim , John Pauly , Jongho Lee
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