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Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

In the context of PDE-constrained optimization theory, source identification problems traditionally entail particles emerging from an unknown source distribution inside a domain, moving according to a prescribed stochastic process,…

Optimization and Control · Mathematics 2025-08-22 Richard B. Lehoucq , Scott A. McKinley , Petr Plecháč

The inference of physical parameters from measured distributions constitutes a core task in physics data analyses. Among recent deep learning methods, so-called conditional invertible neural networks provide an elegant approach owing to…

Instrumentation and Methods for Astrophysics · Physics 2022-03-14 Teresa Bister , Martin Erdmann , Ullrich Köthe , Josina Schulte

Density-ratio estimation via classification is a cornerstone of unsupervised learning. It has provided the foundation for state-of-the-art methods in representation learning and generative modelling, with the number of use-cases continuing…

Machine Learning · Statistics 2020-11-25 Benjamin Rhodes , Kai Xu , Michael U. Gutmann

While many areas of machine learning have benefited from the increasing availability of large and varied datasets, the benefit to causal inference has been limited given the strong assumptions needed to ensure identifiability of causal…

Machine Learning · Computer Science 2022-01-02 Wenshuo Guo , Serena Wang , Peng Ding , Yixin Wang , Michael I. Jordan

We consider settings where the observations are drawn from a zero-mean multivariate (real or complex) normal distribution with the population covariance matrix having eigenvalues of arbitrary multiplicity. We assume that the eigenvectors of…

Statistics Theory · Mathematics 2009-01-22 N. Raj Rao , James A. Mingo , Roland Speicher , Alan Edelman

Completely random measures (CRMs) and their normalizations are a rich source of Bayesian nonparametric priors. Examples include the beta, gamma, and Dirichlet processes. In this paper we detail two major classes of sequential CRM…

Statistics Theory · Mathematics 2020-05-11 Trevor Campbell , Jonathan H. Huggins , Jonathan P. How , Tamara Broderick

Is it possible to detect a feature in an image without ever looking at it? Images are known to have sparser representation in Wavelets and other similar transforms. Compressed Sensing is a technique which proposes simultaneous acquisition…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Suyash Shandilya

In this paper, we consider the problem of locating the information source with sparse observations. We assume that a piece of information spreads in a network following a heterogeneous susceptible-infected-recovered (SIR) model and that a…

Social and Information Networks · Computer Science 2013-09-20 Kai Zhu , Lei Ying

We consider continuous time Markovian processes where populations of individual agents interact stochastically according to kinetic rules. Despite the increasing prominence of such models in fields ranging from biology to smart cities,…

Machine Learning · Statistics 2016-05-16 Anastasis Georgoulas , Jane Hillston , Guido Sanguinetti

We introduce a new approach to prediction in graphical models with latent-shift adaptation, i.e., where source and target environments differ in the distribution of an unobserved confounding latent variable. Previous work has shown that as…

Machine Learning · Statistics 2023-06-26 William I. Walker , Arthur Gretton , Maneesh Sahani

Motivated by the desire to generate labels for real-time data we develop a method to estimate the dependency structure and accuracy of weak supervision sources incrementally. Our method first estimates the dependency structure associated…

Machine Learning · Computer Science 2022-05-12 Richard Gresham Correro

Upcoming next-generation sky surveys will detect large number of faint objects with magnitudes larger than 25. When objects are crowded within a limited a field of view, blending becomes unavoidable. Blending leads to the omission of many…

Instrumentation and Methods for Astrophysics · Physics 2026-03-03 Yibo Yan , Chao Liu , Jiadong Li , Feng Wang

Consider $n$ random variables forming a Markov random field (MRF). The true model of the MRF is unknown, and it is assumed to belong to a binary set. The objective is to sequentially sample the random variables (one-at-a-time) such that the…

Methodology · Statistics 2020-08-04 Javad Heydari , Ali Tajer , H. Vincent Poor

Network structures underlie the dynamics of many complex phenomena, from gene regulation and foodwebs to power grids and social media. Yet, as they often cannot be observed directly, their connectivities must be inferred from observations…

Machine Learning · Computer Science 2023-11-02 Thomas Gaskin , Grigorios A. Pavliotis , Mark Girolami

A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual…

Machine Learning · Computer Science 2025-10-08 Sebastian Wagner-Carena , Aizhan Akhmetzhanova , Sydney Erickson

I discuss an issue arising in analyzing data from astronomical surveys: accounting for measurement uncertainties in the properties of individual sources detected in a survey when making inferences about the entire population of sources.…

Astrophysics · Physics 2009-11-10 Thomas J. Loredo

Self-consistency boosts inference-time performance by sampling multiple reasoning traces in parallel and voting. However, in constrained domains like math and code, this strategy is compute-inefficient because it samples with replacement,…

Machine Learning · Computer Science 2026-04-23 Xueyan Li , Johannes Zenn , Ekaterina Fadeeva , Guinan Su , Mrinmaya Sachan , Jonas Geiping

We introduce a framework for uncertainty estimation that both describes and extends many existing methods. We consider typical hyperparameters involved in classical training as random variables and marginalise them out to capture various…

Machine Learning · Computer Science 2021-07-07 Francesco Farina , Lawrence Phillips , Nicola J Richmond

To facilitate the numerical analysis of particle methods, we derive truncation error estimates for the approximate operators in a generalized particle method. Here, a generalized particle method is defined as a meshfree numerical method…

Numerical Analysis · Mathematics 2019-07-09 Yusuke Imoto