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The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

Neurons and Cognition · Quantitative Biology 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu

Functional neuroimaging measures how the brain responds to complex stimuli. However, sample sizes are modest, noise is substantial, and stimuli are high dimensional. Hence, direct estimates are inherently imprecise and call for…

Applications · Statistics 2016-02-05 Leila Wehbe , Aaditya Ramdas , Rebecca C. Steorts , Cosma Rohilla Shalizi

The $1/f$-like decay observed in the power spectrum of electro-physiological signals, along with scale-free statistics of the so-called neuronal avalanches, constitute evidences of criticality in neuronal systems. Recent in vitro studies…

Neurons and Cognition · Quantitative Biology 2017-08-31 Fabrizio Lombardi , Hans J. Herrmann , Lucilla de Arcangelis

Functional MRI measuring BOLD signal is an increasingly important imaging modality in studying brain functions and neurological disorders. It can be acquired in either a resting-state or a task-based paradigm. Compared to resting-state…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Jiyao Wang , Nicha C. Dvornek , Peiyu Duan , Lawrence H. Staib , James S. Duncan

We characterize the amplitude statistics of intraoperative microelectrode recordings (MERs) obtained during deep brain stimulation (DBS) surgery in 46 patients with Parkinson's disease, using 184 recordings equally balanced between inside…

We consider the problem of localization of sources of brain electrical activity from electroencephalographic (EEG) and magnetoencephalographic (MEG) measurements using spatial filtering techniques. We propose novel reduced-rank activity…

Signal Processing · Electrical Eng. & Systems 2024-08-02 Tomasz Piotrowski , Jan Nikadon , Alexander Moiseev

Electroencephalography (EEG) signals are promising as alternatives to other biometrics owing to their protection against spoofing. Previous studies have focused on capturing individual variability by analyzing task/condition-specific EEG.…

Signal Processing · Electrical Eng. & Systems 2021-03-29 Mari Ganesh Kumar , Shrikanth Narayanan , Mriganka Sur , Hema A Murthy

In the status quo, dementia is yet to be cured. Precise diagnosis prior to the onset of the symptoms can prevent the rapid progression of the emerging cognitive impairment. Recent progress has shown that Electroencephalography (EEG) is the…

Scale-invariant neuronal avalanches have been observed in cell cultures and slices as well as anesthetized and awake brains, suggesting that the brain operates near criticality, i.e. within a narrow margin between avalanche propagation and…

Neurons and Cognition · Quantitative Biology 2011-01-18 Tiago L. Ribeiro , Mauro Copelli , Fábio Caixeta , Hindiael Belchior , Dante R. Chialvo , Miguel A. L. Nicolelis , Sidarta Ribeiro

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Brain decoding that classifies cognitive states using the functional fluctuations of the brain can provide insightful information for understanding the brain mechanisms of cognitive functions. Among the common procedures of decoding the…

Human-Computer Interaction · Computer Science 2024-07-12 Jianfei Zhu , Baichun Wei , Jiaru Tian , Feng Jiang , Chunzhi Yi

Aperiodic activity is a physiologically distinct component of the electrophysiological power spectrum. It is suggested to reflect the balance of excitation and inhibition in the brain, within selected frequency bands. However, the impact of…

Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal and…

Methodology · Statistics 2025-02-07 Jian Zhang , Gary Green

We consider the problem of estimating the difference between two functional undirected graphical models with shared structures. In many applications, data are naturally regarded as high-dimensional random function vectors rather than…

Machine Learning · Statistics 2019-11-19 Boxin Zhao , Y. Samuel Wang , Mladen Kolar

The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are…

Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and…

Brain responses related to working memory originate from distinct brain areas and oscillate at different frequencies. EEG signals with high temporal correlation can effectively capture these responses. Therefore, estimating the functional…

Machine Learning · Computer Science 2024-05-01 Harshini Gangapuram , Vidya Manian

The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…

Statistical Mechanics · Physics 2022-07-08 Guillermo B. Morales , Serena Di Santo , Miguel A. Munoz

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…