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Deep neural networks are often ignorant about what they do not know and overconfident when they make uninformed predictions. Some recent approaches quantify classification uncertainty directly by training the model to output high…

Machine Learning · Computer Science 2020-06-09 Murat Sensoy , Lance Kaplan , Federico Cerutti , Maryam Saleki

In microscopy image cell segmentation, it is common to train a deep neural network on source data, containing different types of microscopy images, and then fine-tune it using a support set comprising a few randomly selected and annotated…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Youssef Dawoud , Arij Bouazizi , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis

The uncertainty in the redshift distributions of galaxies has a significant potential impact on the cosmological parameter values inferred from multi-band imaging surveys. The accuracy of the photometric redshifts measured in these surveys…

Cosmology and Nongalactic Astrophysics · Physics 2011-08-05 Augusta Abrahamse , Lloyd Knox , Samuel Schmidt , Paul Thorman , J. Anthony Tyson , Hu Zhan

Integrating heterogeneous datasets across different measurement platforms is a fundamental challenge in many scientific applications. A common example arises in deconvolution problems, such as cell type deconvolution, where one aims to…

Methodology · Statistics 2025-09-30 Dongyue Xie , Lin Gui , Jingshu Wang

We propose a theoretical motivation to quantify actual physiological features, such as the shape index distributions measured by Jones and Palmer in cats and by Ringach in macaque monkeys. We will adopt the Uncertainty Principle associated…

Cell Behavior · Quantitative Biology 2013-03-05 Davide Barbieri , Giovanna Citti , Alessandro Sarti

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Motivation: The scratch assay is a standard experimental protocol used to characterize cell migration. It can be used to identify genes that regulate migration and evaluate the efficacy of potential drugs that inhibit cancer invasion. In…

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 diabetes. We consider three families of sequence models based on LSTM, GRU, and…

Machine Learning · Computer Science 2026-03-31 Hai Siong Tan , Rafe McBeth

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

A commonly accepted hypothesis is that models with higher accuracy on Imagenet perform better on other downstream tasks, leading to much research dedicated to optimizing Imagenet accuracy. Recently this hypothesis has been challenged by…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Niv Nayman , Avram Golbert , Asaf Noy , Tan Ping , Lihi Zelnik-Manor

Conformal inference is a method that provides prediction sets for machine learning models, operating independently of the underlying distributional assumptions and relying solely on the exchangeability of training and test data. Despite its…

Methodology · Statistics 2025-10-01 Daniela Corbetta , Livio Finos , Ludwig Geistlinger , Davide Risso

Uncertainty estimation is important for interpreting the trustworthiness of machine learning models in many applications. This is especially critical in the data-driven active learning setting where the goal is to achieve a certain accuracy…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Bo Li , Tommy Sonne Alstrøm

Measuring uncertainties in the output of a deep learning method is useful in several ways, such as in assisting with interpretation of the outputs, helping build confidence with end users, and for improving the training and performance of…

Machine Learning · Computer Science 2022-09-20 Luke Whitbread , Mark Jenkinson

While clustering is ubiquitously used across science and industry, uncertainty in cluster assignments is rarely quantified with rigorous guarantees. We propose a novel conformal inference framework for clustering that returns confidence…

Methodology · Statistics 2026-04-13 YoonHaeng Hur , Anirban Nath , Genevera Allen

Uncertainty Sampling is an Active Learning strategy that aims to improve the data efficiency of machine learning models by iteratively acquiring labels of data points with the highest uncertainty. While it has proven effective for…

Machine Learning · Computer Science 2025-02-28 Dominik Fuchsgruber , Tom Wollschläger , Bertrand Charpentier , Antonio Oroz , Stephan Günnemann

Unsupervised domain adaptation methods seek to generalize effectively on unlabeled test data, especially when encountering the common challenge in time series data that distribution shifts occur between training and testing datasets. In…

Machine Learning · Computer Science 2025-08-27 Weide Liu , Xiaoyang Zhong , Lu Wang , Jingwen Hou , Yuemei Luo , Jiebin Yan , Yuming Fang

Single-cell technologies are revolutionizing the entire field of biology. The large volumes of data generated by single-cell technologies are high-dimensional, sparse, heterogeneous, and have complicated dependency structures, making…

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

This paper introduces a novel uncertainty quantification framework for regression models where the response takes values in a separable metric space, and the predictors are in a Euclidean space. The proposed algorithms can efficiently…

Statistics Theory · Mathematics 2024-05-09 Gábor Lugosi , Marcos Matabuena

Modern machine learning methods including deep learning have achieved great success in predictive accuracy for supervised learning tasks, but may still fall short in giving useful estimates of their predictive {\em uncertainty}. Quantifying…

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