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Group-testing refers to the problem of identifying (with high probability) a (small) subset of $D$ defectives from a (large) set of $N$ items via a "small" number of "pooled" tests. For ease of presentation in this work we focus on the…

Information Theory · Computer Science 2013-07-11 Sheng Cai , Mohammad Jahangoshahi , Mayank Bakshi , Sidharth Jaggi

The practice of pooling several individual test statistics to form aggregate tests is common in many statistical application where individual tests may be underpowered. While selection by aggregate tests can serve to increase power, the…

Methodology · Statistics 2020-12-08 Ruth Heller , Amit Meir , Nilanjan Chatterjee

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

Machine Learning · Computer Science 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Under limited available resources, strategies for mitigating the propagation of an epidemic such as random testing and contact tracing become inefficient. Here, we propose to accurately allocate the resources by computing over time an…

Physics and Society · Physics 2023-11-07 Gabriela Bayolo Soler , Miraine Dávila Felipe , Ghislaine Gayraud

In group testing, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether at least one defective item is present. This problem is relevant in areas such as medical…

Information Theory · Computer Science 2022-10-24 Eric Price , Jonathan Scarlett , Nelvin Tan

Mitigation strategies that remove infectious individuals from the greater population have to balance their efficacy with the economic effects associated with quarantine and have to contend with the limited resources available to the public…

Quantitative Methods · Quantitative Biology 2020-12-09 Ted Londner , Jonathan Saunders , Dieter W. Schuldt , Bill Streilein

We consider the problem of recovering an unknown signal ${\mathbf x}\in {\mathbb R}^n$ from general nonlinear measurements obtained through a generalized linear model (GLM), i.e., ${\mathbf y}= f\left({\mathbf A}{\mathbf x}+{\mathbf…

Information Theory · Computer Science 2022-10-18 Jiang Zhu , Xiangming Meng , Xupeng Lei , Qinghua Guo

Detection of rare traits or diseases in a large population is challenging. Pool testing allows covering larger swathes of population at a reduced cost, while simplifying logistics. However, testing precision decreases as it becomes unclear…

Information Theory · Computer Science 2021-06-22 Éric Brier , Megi Dervishi , Rémi Géraud-Stewart , David Naccache , Ofer Yifrach-Stav

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

Sparse Group LASSO (SGL) is a regularized model for high-dimensional linear regression problems with grouped covariates. SGL applies $l_1$ and $l_2$ penalties on the individual predictors and group predictors, respectively, to guarantee…

Statistics Theory · Mathematics 2022-02-23 Kan Chen , Zhiqi Bu , Shiyun Xu

We study Dorfman's classical group testing protocol in a novel setting where individual specimen statuses are modeled as exchangeable random variables. We are motivated by infectious disease screening. In that case, specimens which arrive…

Applications · Statistics 2024-02-28 Nicholas C. Landolfi , Sanjay Lall

We describe a generalization of the group testing problem termed symmetric group testing. Unlike in classical binary group testing, the roles played by the input symbols zero and one are "symmetric" while the outputs are drawn from a…

Information Theory · Computer Science 2011-08-16 Amin Emad , Jun Shen , Olgica Milenkovic

We study the group testing problem where the goal is to identify a set of k infected individuals carrying a rare disease within a population of size n, based on the outcomes of pooled tests which return positive whenever there is at least…

Machine Learning · Statistics 2022-06-16 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Alexander S. Wein , Ilias Zadik

The generalized approximate message passing (GAMP) algorithm is an efficient method of MAP or approximate-MMSE estimation of $x$ observed from a noisy version of the transform coefficients $z = Ax$. In fact, for large zero-mean i.i.d…

Information Theory · Computer Science 2015-08-11 Jeremy Vila , Philip Schniter , Sundeep Rangan , Florent Krzakala , Lenka Zdeborova

We formulate and analyze a stochastic threshold group testing problem motivated by biological applications. Here a set of $n$ items contains a subset of $d \ll n$ defective items. Subsets (pools) of the $n$ items are tested -- the test…

Information Theory · Computer Science 2013-04-25 Chun Lam Chan , Sheng Cai , Mayank Bakshi , Sidharth Jaggi , Venkatesh Saligrama

The estimation of a random vector with independent components passed through a linear transform followed by a componentwise (possibly nonlinear) output map arises in a range of applications. Approximate message passing (AMP) methods, based…

Information Theory · Computer Science 2016-05-03 Sundeep Rangan , Philip Schniter , Erwin Riegler , Alyson Fletcher , Volkan Cevher

In order to identify the infected individuals of a population, their samples are divided in equally sized groups called pools and a single laboratory test is applied to each pool. Individuals whose samples belong to pools that test negative…

Statistics Theory · Mathematics 2021-10-06 Inés Armendáriz , Pablo A. Ferrari , Daniel Fraiman , José M. Martínez , Silvina Ponce Dawson

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

Populations and Evolution · Quantitative Biology 2021-06-16 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

The goal of the group testing problem is to identify a set of defective items within a larger set of items, using suitably-designed tests whose outcomes indicate whether any defective item is present. In this paper, we study how the number…

Information Theory · Computer Science 2023-01-18 Ivan Lau , Jonathan Scarlett , Yang Sun

Generalized approximate message passing (GAMP) is a computationally efficient algorithm for estimating an unknown signal $w_0\in\mathbb{R}^N$ from a random linear measurement $y= Xw_0 + \epsilon\in\mathbb{R}^M$, where…

Information Theory · Computer Science 2025-08-06 Takashi Takahashi