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We investigate the evolutionary dynamics of a population structured in phenotype, subjected to trait dependent selection with a linearly moving optimum and an asexual mode of reproduction. Our model consists of a non-local and non-linear…

Analysis of PDEs · Mathematics 2021-12-09 Raphaël Forien , Jimmy Garnier , Florian Patout

Mendelian randomization (MR) is a natural experimental design based on the random transmission of genes from parents to offspring. However, this inferential basis is typically only implicit or used as an informal justification. As…

Methodology · Statistics 2023-04-19 Matthew J Tudball , George Davey Smith , Qingyuan Zhao

We consider a population with non-overlapping generations, whose size goes to infinity. It is described by a discrete genealogy which may be time non-homogeneous and we pay special attention to branching trees in varying environments. A…

Probability · Mathematics 2013-05-22 Vincent Bansaye , Chunmao Huang

We consider a Moran-type model of cultural evolution, which describes how traits emerge, are transmitted, and get lost in populations. Our analysis focuses on the underlying cultural genealogies; they were first described by Aguilar and…

Populations and Evolution · Quantitative Biology 2026-02-04 Joe Yuichiro Wakano , Hisashi Ohtsuki , Yutaka Kobayashi , Ellen Baake

Infinitely many distinct trait values may arise in populations bearing quantitative traits, and modeling their population dynamics is thus a formidable task. While classical models assume fixed or infinite population size, models in which…

Populations and Evolution · Quantitative Biology 2025-05-08 Ananda Shikhara Bhat

Adaptive dynamics so far has been put on a rigorous footing only for clonal inheritance. We extend this to sexually reproducing diploids, although admittedly still under the restriction of an unstructured population with Lotka-Volterra-like…

Probability · Mathematics 2011-11-29 Pierre Collet , Sylvie Méléard , J. A. J. Metz

Just as the $\lambda$-calculus uses three primitives (abstraction, application, variable) as the foundation of functional programming, inheritance-calculus uses three primitives (record, definition, inheritance) as the foundation of…

Programming Languages · Computer Science 2026-05-27 Bo Yang

In genetic studies of complex diseases, the underlying mode of inheritance is often not known. Thus, the most powerful test or other optimal procedure for one model, e.g. recessive, may be quite inefficient if another model, e.g. dominant,…

Statistics Theory · Mathematics 2007-06-13 Gang Zheng , Boris Freidlin , Joseph L. Gastwirth

Inequality in human success may emerge through endogenous success-breeds-success dynamics but may also originate in pre-existing differences in talent. It is widely recognized that the skew in static frequency distributions of success…

Probability · Mathematics 2023-10-06 Alexandros Gelastopoulos , Lucas Sage , Arnout van de Rijt

In the field of genetics, the concept of heritability refers to the proportion of variations of a biological trait or disease that can be explained by genetic factors. Quantifying the heritability of a disease is a fundamental challenge in…

Statistics Theory · Mathematics 2016-11-10 Anna Bonnet

Infinitesimal gradient boosting (Dombry and Duchamps, 2021) is defined as the vanishing-learning-rate limit of the popular tree-based gradient boosting algorithm from machine learning. It is characterized as the solution of a nonlinear…

Machine Learning · Statistics 2023-07-13 Clement Dombry , Jean-Jil Duchamps

We consider a branching model in discrete time where each individual has a trait in some general state space. Both the reproduction law and the trait inherited by the offsprings may depend on the trait of the mother and the environment. We…

Probability · Mathematics 2013-11-26 Vincent Bansaye

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

In a previous paper (called "Rectangular random matrices. Related covolution"), we defined, for $\lambda \in [0,1]$, the rectangular free convolution with ratio $\lambda$. Here, we investigate the related notion of infinite divisiblity,…

Operator Algebras · Mathematics 2007-05-23 Florent Benaych-Georges

In this work we model the dynamics of a population that evolves as a continuous time branching process with a trait structure and ecological interactions in form of mutations and competition between individuals. We generalize existing…

Probability · Mathematics 2020-10-19 Gabriel Berzunza , Anja Sturm , Anita Winter

A key goal in studies of ecology and evolution is understanding the causes of phenotypic diversity in nature. Most traits of interest, such as those relating to morphology, life-history, immunity and behaviour are quantitative, and…

Populations and Evolution · Quantitative Biology 2022-11-22 Susan E. Johnston , Nancy Chen , Emily B. Josephs

In this paper we analyse the genetic evolution of a diploid hermaphroditic population, which is modelled by a three-type nonlinear birth-and-death process with competition and Mendelian reproduction. In a recent paper, Collet et al., 2013…

Probability · Mathematics 2017-08-28 Anton Bovier , Rebecca Neukirch

Heritability is a central concept in the long-standing debate about nature versus nurture in biological and social sciences. However, existing notions of heritability are based on strong assumptions and do not use explicit causal models. We…

Applications · Statistics 2026-05-26 Haochen Lei , Jieru Shi , Hongyuan Cao , Qingyuan Zhao

We reconsider the deterministic haploid mutation-selection equation with two types. This is an ordinary differential equation that describes the type distribution (forward in time) in a population of infinite size. This paper establishes…

Probability · Mathematics 2020-09-25 Ellen Baake , Fernando Cordero , Sebastian Hummel

The process of evolutionary diversification unfolds in a vast genotypic space of potential outcomes. During the past century there have been remarkable advances in the development of theory for this diversification, and the theory's success…

Populations and Evolution · Quantitative Biology 2011-10-14 Troy Day