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Compressed streak imaging (CSI) is a computational imaging strategy that can acquire video at over 150 trillion frames per second. Despite this achievement, CSI faces challenges in detecting subtle intensity fluctuations in slow-moving,…

Fluorescence Molecular Tomography (FMT) is a widely used non-invasive optical imaging technology in biomedical research. It usually faces significant accuracy challenges in depth reconstruction, and conventional iterative methods struggle…

Numerical Analysis · Mathematics 2025-10-08 Ruchi Guo , Jiahua Jiang , Bangti Jin , Wuwei Ren , Jianru Zhang

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Speeding up the data acquisition is one of the central aims to advance tomographic imaging. On the one hand, this reduces motion artifacts due to undesired movements, and on the other hand this decreases the examination time for the…

Numerical Analysis · Mathematics 2015-01-20 Michael Sandbichler , Felix Krahmer , Thomas Berer , Peter Burgholzer , Markus Haltmeier

While transmission electron microscopes (TEM) can achieve a much higher resolution than optical microscopes, they face challenges of damage to samples during the high energy processes involved. Here, we explore using computational ghost…

Compressed sensing can increase resolution, and decrease electron dose and scan time of electron microscope point-scan systems with minimal information loss. Building on a history of successful deep learning applications in compressed…

Image and Video Processing · Electrical Eng. & Systems 2019-10-28 Jeffrey M. Ede

The goal in signal compression is to reduce the size of the input signal without a significant loss in the quality of the recovered signal. One way to achieve this goal is to apply the principles of compressive sensing, but this has not…

Signal Processing · Electrical Eng. & Systems 2020-03-09 Fereshteh Fakhar Firouzeh , John W. Chinneck , Sreeraman Rajan

While deep neural networks (NN) significantly advance image compressed sensing (CS) by improving reconstruction quality, the necessity of training current CS NNs from scratch constrains their effectiveness and hampers rapid deployment.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Chen , Zhenyu Zhang , Weiqi Li , Chen Zhao , Jiwen Yu , Shijie Zhao , Jie Chen , Jian Zhang

Optical imaging of quantum emitters is essential for a wide range of quantum applications. Conventional confocal imaging relies on point-by-point raster scanning, which is inherently time-consuming and photon-inefficient, particularly for…

Nanoscale focused ion beams (FIBs) represent one of the most useful tools in nanotechnology, enabling nanofabrication via milling and gas-assisted deposition, microscopy and microanalysis, and selective, spatially resolved doping of…

Atomic Physics · Physics 2021-06-09 J. J. McClelland , A. V. Steele , B. Knuffman , K. A. Twedt , A. Schwarzkopf , T. M. Wilson

Different tasks in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM) require enhancing the quality of the highly noisy raw images. To this end, we develop an efficient algorithm for signal enhancement of…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Guy Sharon , Yoel Shkolnisky , Tamir Bendory

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

Focused ion beams (FIBs) are widely used to modify optoelectronic devices, but their utility is severely restricted in some III-V materials due to adverse effects such as nanofibre growth and contamination. This study describes an effective…

Applied Physics · Physics 2019-06-17 Pierce Maguire , Darragh Keane , Brian Kelly , Colm C. Faulkner , Hongzhou Zhang

Existing Masked Image Modeling (MIM) depends on a spatial patch-based masking-reconstruction strategy to perceive objects'features from unlabeled images, which may face two limitations when applied to chest CT: 1) inefficient feature…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Jie Zheng , Ru Wen , Haiqin Hu , Lina Wei , Kui Su , Wei Chen , Chen Liu , Jun Wang

Doubly selective (DS) channel estimation in largescale multiple-input multiple-output (MIMO) systems is a challenging problem due to the requirement of unaffordable pilot overheads and prohibitive complexity. In this paper, we propose a…

Information Theory · Computer Science 2015-11-10 Bo Gong , Qibo Qin , Xiang Ren , Lin Gui , Hanwen Luo , Wen Chen

Fourier ptychographic microscopy (FPM) is a pivotal computational imaging technique that achieves phase and amplitude reconstruction with high resolution and wide field of view, using low numerical aperture objectives and LED array…

Modern electron tomography has progressed to higher resolution at lower doses by leveraging compressed sensing methods that minimize total variation (TV). However, these sparsity-emphasized reconstruction algorithms introduce tunable…

Medical Physics · Physics 2023-09-12 William Millsaps , Jonathan Schwartz , Zichao Wendy Di , Yi Jiang , Robert Hovden

Compressed sensing (CS) is a powerful method routinely employed to accelerate image acquisition. It is particularly suited to situations when the image under consideration is sparse but can be sampled in a basis where it is non-sparse. Here…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 Xudong Lv , Ashok Ajoy

Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature, it has the potential to provide…

To optimize diffusion MRI acquisition protocols for IMPULSED model at clinical 3T scanner using Bayesian experimental design, enabling accurate cellular-scale parameter estimation under realistic scan time and scanner hardware constraints.…

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