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Sleep staging is fundamental for sleep assessment and disease diagnosis. Although previous attempts to classify sleep stages have achieved high classification performance, several challenges remain open: 1) How to effectively extract…

Machine Learning · Computer Science 2021-05-31 Ziyu Jia , Youfang Lin , Jing Wang , Xuehui Wang , Peiyi Xie , Yingbin Zhang

Clinical adoption of deep learning models has been hindered, in part, because the black-box nature of neural networks leads to concerns regarding their trustworthiness and reliability. These concerns are particularly relevant in the field…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Lindsay Munroe , Mariana da Silva , Faezeh Heidari , Irina Grigorescu , Simon Dahan , Emma C. Robinson , Maria Deprez , Po-Wah So

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Automatic sleep staging commonly adopts Transformers under the assumption that they learn complex long-range dependencies. We challenge this view by revealing a neglected property of sleep sequences: strong local temporal continuity. We…

Machine Learning · Computer Science 2026-05-12 Guisong Liu , Xin Gao , Martin Dresler , Jiansong Zhang , Pengfei Wei

In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming…

Computers and Society · Computer Science 2020-06-25 Lichin Chen , Yu Tsao , Ji-Tian Sheu

Sleep staging is a key method for assessing sleep quality and diagnosing sleep disorders. However, current deep learning methods face challenges: 1) postfusion techniques ignore the varying contributions of different modalities; 2)…

Machine Learning · Computer Science 2025-02-21 Chenjun Zhao , Xuesen Niu , Xinglin Yu , Long Chen , Na Lv , Huiyu Zhou , Aite Zhao

Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore,…

Machine Learning · Statistics 2018-08-20 Sebastien Dubois , Nathanael Romano , David C. Kale , Nigam Shah , Kenneth Jung

Sleep stage classification constitutes an important element of sleep disorder diagnosis. It relies on the visual inspection of polysomnography records by trained sleep technologists. Automated approaches have been designed to alleviate this…

Quantitative Methods · Quantitative Biology 2020-04-28 Antoine Guillot , Fabien Sauvet , Emmanuel H During , Valentin Thorey

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

Neurons and Cognition · Quantitative Biology 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

Sleep posture is linked to several health conditions such as nocturnal cramps and more serious musculoskeletal issues. However, in-clinic sleep assessments are often limited to vital signs (e.g. brain waves). Wearable sensors with embedded…

Machine Learning · Computer Science 2022-05-24 Omar Elnaggar , Frans Coenen , Andrew Hopkinson , Lyndon Mason , Paolo Paoletti

Despite continued advancement in machine learning algorithms and increasing availability of large data sets, there is still no universally acceptable solution for automatic sleep staging of human sleep recordings. One reason is that a…

Neurons and Cognition · Quantitative Biology 2018-01-10 Kaare Mikkelsen , Maarten de Vos

Automating sleep staging is vital to scale up sleep assessment and diagnosis to serve millions experiencing sleep deprivation and disorders and enable longitudinal sleep monitoring in home environments. Learning from raw polysomnography…

Signal Processing · Electrical Eng. & Systems 2021-04-06 Huy Phan , Oliver Y. Chén , Minh C. Tran , Philipp Koch , Alfred Mertins , Maarten De Vos

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Understanding specifically where a model focuses on within an image is critical for human interpretability of the decision-making process. Deep learning-based solutions are prone to learning coincidental correlations in training datasets,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Aidan Boyd , Mohamed Trabelsi , Huseyin Uzunalioglu , Dan Kushnir

Most efforts in interpretability in deep learning have focused on (1) extracting explanations of a specific downstream task in relation to the input features and (2) imposing constraints on the model, often at the expense of predictive…

Machine Learning · Computer Science 2022-02-22 Marco Bertolini , Djork-Arné Clevert , Floriane Montanari

We propose a neuro-symbolic architecture that learns four interpretable physiological concepts, oculomotor dynamics, gaze stability, prefrontal hemodynamics, and multimodal, from eye-tracking and neural hemodynamics, functional…

Human-Computer Interaction · Computer Science 2026-03-26 Mohammadreza Jamalifard , Yaxiong Lei , Parasto Azizinezhad , Javier Fumanal-Idocin , Javier Andreu-Perez

Machine learning is permeating every conceivable domain to promote data-driven decision support. The focus is often on advanced black-box models due to their assumed performance advantages, whereas interpretable models are often associated…

Machine Learning · Computer Science 2024-09-24 Sven Kruschel , Nico Hambauer , Sven Weinzierl , Sandra Zilker , Mathias Kraus , Patrick Zschech

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

In practical sleep stage classification, a key challenge is the variability of EEG data across different subjects and environments. Differences in physiology, age, health status, and recording conditions can lead to domain shifts between…

Signal Processing · Electrical Eng. & Systems 2025-01-08 Siyuan Zhao , Chenyu Liu , Yi Ding , Xinliang Zhou

Being able to interpret, or explain, the predictions made by a machine learning model is of fundamental importance. This is especially true when there is interest in deploying data-driven models to make high-stakes decisions, e.g. in…

Machine Learning · Computer Science 2019-10-01 An-phi Nguyen , María Rodríguez Martínez