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Schizophrenia is a complex psychiatric disorder involving changes in thought patterns, perception, mood, and behavior. The diagnosis of schizophrenia is challenging and requires that patients show two or more positive symptoms for at least…

Machine Learning · Computer Science 2021-02-17 Maritza Tynes , Mahboobeh Parsapoor

Counting fish larvae is an important, yet demanding and time consuming, task in aquaculture. In order to address this problem, in this work, we evaluate four neural network architectures, including convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Daniel Ortega de Carvalho , Luiz Felipe Teodoro Monteiro , Fernanda Marques Bazilio , Gabriel Toshio Hirokawa Higa , Hemerson Pistori

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early…

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially…

Complex systems may contain heterogeneous types of variables that interact in a multi-level and multi-scale manner. In this context, high-level layers may considered as groups of variables interacting in lower-level layers. This is…

Quantitative Methods · Quantitative Biology 2018-11-28 Veronica Tozzo , Federico Tomasi , Margherita Squillario , Annalisa Barla

Serious games have proven to be effective tools for screening cognitive impairments and supporting diagnosis in patients with neurodegenerative diseases like Alzheimer's and Parkinson's. They also offer cognitive training benefits.…

Formal Languages and Automata Theory · Computer Science 2026-02-04 Elisabetta De Maria , Christopher Leturc

Zebrafish pretectal neurons exhibit specificities for large-field optic flow patterns associated with rotatory or translatory body motion. We investigate the hypothesis that these specificities reflect the input statistics of natural optic…

Neurons and Cognition · Quantitative Biology 2018-10-10 Gerrit A. Ecke , Fabian A. Mikulasch , Sebastian A. Bruijns , Thede Witschel , Aristides B. Arrenberg , Hanspeter A. Mallot

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

One of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the progression is diagnosing it in the early…

Machine Learning · Computer Science 2023-10-23 Md. Taufiqul Haque Khan Tusar , Md. Touhidul Islam , Abul Hasnat Sakil

Alzheimer's disease is the most common cause of dementia, yet hard to diagnose precisely without invasive techniques, particularly at the onset of the disease. This work approaches image analysis and classification of synthetic…

Image and Video Processing · Electrical Eng. & Systems 2017-12-05 Wellington Pinheiro dos Santos , Ricardo Emmanuel de Souza , Plínio B. dos Santos Filho

The preclinical stage of many neurodegenerative diseases can span decades before symptoms become apparent. Understanding the sequence of preclinical biomarker changes provides a critical opportunity for early diagnosis and effective…

Methodology · Statistics 2024-06-11 Yizhen Xu , Scott Zeger , Zheyu Wang

The sonar images provide a rapid view of the seabed in order to characterize it. However, in such as uncertain environment, real seabed is unknown and the only information we can obtain, is the interpretation of different human experts,…

Computer Vision and Pattern Recognition · Computer Science 2008-12-18 Arnaud Martin , Christophe Osswald

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

This paper presents a multitask deep learning model to detect all the five stages of diabetic retinopathy (DR) consisting of no DR, mild DR, moderate DR, severe DR, and proliferate DR. This multitask model consists of one classification…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Sharmin Majumder , Nasser Kehtarnavaz

This study conducts an empirical examination of MLP networks investigated through a rigorous methodical experimentation process involving three diverse datasets: TinyFace, Heart Disease, and Iris. Study Overview: The study includes three…

Machine Learning · Computer Science 2025-06-13 Mohammad Subhi Al-Batah , Mowafaq Salem Alzboon , Muhyeeddin Alqaraleh

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research.…

Machine Learning · Computer Science 2018-12-04 Wenyuan Li , Yunlong Wang , Yong Cai , Corey Arnold , Emily Zhao , Yilian Yuan

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

Applications · Statistics 2017-05-18 Jue Wang , Sheng Luo , Liang Li

The increasing access to brain signal data using electroencephalography creates new opportunities to study electrophysiological brain activity and perform ambulatory diagnoses of neuronal diseases. This work proposes a pairwise distance…

Machine Learning · Computer Science 2019-09-09 David Calhas , Enrique Romero , Rui Henriques

Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerged as a powerful tool to enhance PD classification and diagnostic accuracy, particularly by…

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