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Zebrafish embryos are a valuable model for drug discovery due to their optical transparency and genetic similarity to humans. However, current evaluations rely on manual inspection, which is costly and labor-intensive. While machine…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Sarath Sivaprasad , Hui-Po Wang , Anna-Lisa Jäckel , Jonas Baumann , Carole Baumann , Jennifer Herrmann , Mario Fritz

Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal…

Neurons and Cognition · Quantitative Biology 2007-05-23 Scott A. Hill , Xiao-Ping Liu , Melissa A. Borla , Jorge V. Jose , Donald M. O'Malley

Collective movements are pervasive behaviours among social organisms and have led to the development of many models. However, modelling animal trajectories and social interactions in simple bounded environments remains a challenge.…

Neurons and Cognition · Quantitative Biology 2018-11-28 Leo Cazenille , Nicolas Bredeche , José Halloy

In this work we present a novel publicly available stereo based 3D RGB dataset for multi-object zebrafish tracking, called 3D-ZeF. Zebrafish is an increasingly popular model organism used for studying neurological disorders, drug addiction,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Malte Pedersen , Joakim Bruslund Haurum , Stefan Hein Bengtson , Thomas B. Moeslund

The tracing of neural pathways through large volumes of image data is an incredibly tedious and time-consuming process that significantly encumbers progress in neuroscience. We are exploring deep learning's potential to automate…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Ishtar Nyawira , Kristi Bushman , Iris Qian , Annie Zhang

Data-driven benchmarks have led to significant progress in key scientific modeling domains including weather and structural biology. Here, we introduce the Zebrafish Activity Prediction Benchmark (ZAPBench) to measure progress on the…

In the field of environmental toxicology, rapid and precise assessment of the inflammatory response to pollutants in biological models is critical. This study leverages the power of deep learning to enable automated assessments of…

Biological Physics · Physics 2024-06-04 Lulu Xu , Peiwu Qin , Zhenglin Chen , Jiaqi Yang

Zebrafish is an excellent model organism, which has been widely used in the fields of biological experiments, drug screening, and swarm intelligence. In recent years, there are a large number of techniques for tracking of zebrafish involved…

Computer Vision and Pattern Recognition · Computer Science 2022-08-10 Heng Cong , Mingzhu Sun , Duoying Zhou , Xin Zhao

Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…

Machine Learning · Computer Science 2024-12-25 Majid Ali , Hina Shakir , Asia Samreen , Sohaib Ahmed

Collective motion is one of the most ubiquitous behaviours displayed by social organisms and has led to the development of numerous models. Recent advances in the understanding of sensory system and information processing by animals impel…

Biological Physics · Physics 2016-01-28 Bertrand Collignon , Axel Séguret , José Halloy

Larval zebrafish hunting provides a tractable setting to study how ecological and energetic constraints shape adaptive behavior in both biological brains and artificial agents. Here we develop a minimal agent-based model, training recurrent…

Neurons and Cognition · Quantitative Biology 2025-10-07 Raaghav Malik , Satpreet H. Singh , Sonja Johnson-Yu , Nathan Wu , Roy Harpaz , Florian Engert , Kanaka Rajan

Most living organisms show highly conserved physiological changes following a 24-hour cycle which goes by the name of circadian rhythm. Among experimental models, the effects of light-dark cycle have been recently investigated in the larval…

Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of…

Zebrafish share a high degree of homology with human genes and are commonly used as model organism in biomedical research. For medical laboratories, counting zebrafish is a daily task. Due to the tiny size of zebrafish, manual visual…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Qianghua Chen , Huiyu Wang , Li Ming , Ying Zhao

Individual computations and social interactions underlying collective behavior in groups of animals are of great ethological, behavioral, and theoretical interest. While complex individual behaviors have successfully been parsed into small…

Neurons and Cognition · Quantitative Biology 2022-06-08 Roy Harpaz , Gašper Tkačik , Elad Schneidman

Self-organized pattern behavior is ubiquitous throughout nature, from fish schooling to collective cell dynamics during organism development. Qualitatively these patterns display impressive consistency, yet variability inevitably exists…

Quantitative Methods · Quantitative Biology 2022-06-08 Melissa R. McGuirl , Alexandria Volkening , Björn Sandstede

Social behavior across animal species ranges from simple pairwise interactions to thousands of individuals coordinating goal-directed movements. Regardless of the scale, these interactions are governed by the interplay between multimodal…

Neurons and Cognition · Quantitative Biology 2024-08-06 Sarah Josephine Stednitz , Andrew Lesak , Adeline L Fecker , Peregrine Painter , Phil Washbourne , Luca Mazzucato , Ethan K Scott

In this paper, we explore deep learning techniques for individual identification of animals based on their skin patterns. Individual identification is crucial in biodiversity monitoring, since it enables analysis of decline or growth of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Jens van Bijsterveld , Daniele Avitabile , Fons J. Verbeek , Rita Pucci

Imaging and genomic data offer distinct and rich features, and their integration can unveil new insights into the complex landscape of diseases. In this study, we present a novel approach utilizing radiogenomic data including structural MRI…

Machine Learning · Computer Science 2025-05-16 Aditya Raj , Golrokh Mirzaei

Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica
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