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Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

With the introduction of fully convolutional neural networks, deep learning has raised the benchmark for medical image segmentation on both speed and accuracy, and different networks have been proposed for 2D and 3D segmentation with…

Computer Vision and Pattern Recognition · Computer Science 2018-09-26 Ken C. L. Wong , Mehdi Moradi , Hui Tang , Tanveer Syeda-Mahmood

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Purpose: To implement a brain segmentation pipeline based on convolutional neural networks, which rapidly segments 3D volumes into 27 anatomical structures. To provide an extensive, comparative study of segmentation performance on various…

Image and Video Processing · Electrical Eng. & Systems 2020-08-12 Jonathan Zopes , Moritz Platscher , Silvio Paganucci , Christian Federau

Accurate segmentation of infant brain MRI is critical for studying early neurodevelopment and diagnosing neurological disorders. Yet, it remains a fundamental challenge due to continuously evolving anatomy of the subjects, motion artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Alemu Sisay Nigru , Michele Svanera , Austin Dibble , Connor Dalby , Mattia Savardi , Sergio Benini

Detailed whole brain segmentation is an essential quantitative technique, which provides a non-invasive way of measuring brain regions from a structural magnetic resonance imaging (MRI). Recently, deep convolution neural network (CNN) has…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Yuankai Huo , Zhoubing Xu , Yunxi Xiong , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Longitudinal brain MRI is essential for characterizing the progression of neurological diseases such as Alzheimer's disease assessment. However, current deep-learning tools fragment this process: classifiers reduce a scan to a label,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zhaoyang Jiang , Zhizhong Fu , David McAllister , Yunsoo Kim , Honghan Wu

Whole brain segmentation is an important neuroimaging task that segments the whole brain volume into anatomically labeled regions-of-interest. Convolutional neural networks have demonstrated good performance in this task. Existing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Yeshu Li , Jonathan Cui , Yilun Sheng , Xiao Liang , Jingdong Wang , Eric I-Chao Chang , Yan Xu

Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy. Historically, multi-atlas segmentation (MAS) has been regarded as the de facto standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Yuankai Huo , Zhoubing Xu , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Mengqi Wu , Minhui Yu , Shuaiming Jing , Pew-Thian Yap , Zhengwu Zhang , Mingxia Liu

The volume of a brain lesion (e.g. infarct or tumor) is a powerful indicator of patient prognosis and can be used to guide the therapeutic strategy. Lesional volume estimation is usually performed by segmentation with deep convolutional…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 Benjamin Lambert , Florence Forbes , Senan Doyle , Michel Dojat

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

In this study, we proposed and validated a multi-atlas guided 3D fully convolutional network (FCN) ensemble model (M-FCN) for segmenting brain regions of interest (ROIs) from structural magnetic resonance images (MRIs). One major limitation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiong Wu , Xiaoying Tang

Segmentation of brain structures on MRI is the primary step for further quantitative analysis of brain diseases. Manual segmentation is still considered the gold standard in terms of accuracy; however, such data is extremely time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Mengyu Li , Magnus Magnusson , Thilo van Eimeren , Lotta M. Ellingsen

Purpose. Brain Magnetic Resonance Images (MRIs) are essential for the diagnosis of neurological diseases. Recently, deep learning methods for unsupervised anomaly detection (UAD) have been proposed for the analysis of brain MRI. These…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Marcel Bengs , Finn Behrendt , Julia Krüger , Roland Opfer , Alexander Schlaefer

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour
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