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Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another…

Machine Learning · Computer Science 2022-07-07 Mohammadreza Nemati , Haonan Zhang , Michael Sloma , Dulat Bekbolsynov , Hong Wang , Stanislaw Stepkowski , Kevin S. Xu

Kidney Exchange Programs (KEPs) promote access to living donor trans- plantation for patients suffering from end stage renal disease. The HLA compatibility between transplant recipients and donors plays an important role when solving the…

Optimization and Control · Mathematics 2025-10-17 Valentina Peralta Clarke , Hans de Ferrante , Francisco Perez Galarce , Joris van de Klundert

Five year post-transplant survival rate is an important indicator on quality of care delivered by kidney transplant centers in the United States. To provide a fair assessment of each transplant center, an effect that represents the…

Applications · Statistics 2017-03-13 Lanfeng Pan , Yehua Li , Kevin He , Yanming Li , Yi Li

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…

Computers and Society · Computer Science 2019-08-22 Ehsan Khan , Avishek Choudhury , Amy L Friedman , Daehan Won

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

This paper presents a comprehensive review of the last two decades of research on Kidney Exchange Programs (KEPs), systematically categorizing and classifying key contributions to provide readers with a structured understanding of…

Artificial Intelligence · Computer Science 2025-02-13 Shayan Sharifi

Capturing the inter-dependencies among multiple types of clinically-critical events is critical not only to accurate future event prediction, but also to better treatment planning. In this work, we propose a deep latent state-space…

Machine Learning · Computer Science 2024-07-30 Yuan Xue , Denny Zhou , Nan Du , Andrew M. Dai , Zhen Xu , Kun Zhang , Claire Cui

Incompatibility between patient and donor is a major barrier in kidney transplantation (KT). The increasing shortage of kidney donors has driven the development of desensitization techniques to overcome this immunological challenge.…

Systems and Control · Electrical Eng. & Systems 2025-04-29 Xingyu Ren , Michael C. Fu , Steven I. Marcus

Liver transplant can be a life-saving procedure for patients with end-stage liver disease. With the introduction of modern immunosuppressive therapies, short-term survival has significantly improved. However, long-term survival has not…

Quantitative Methods · Quantitative Biology 2024-11-28 Julia Bruner , Kyle Adams , Skylar Grey , Mahya Aghaee , Sergio Duarte , Ali Zarrinpar , Helen Moore

Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another…

Computer Science and Game Theory · Computer Science 2017-10-24 Sommer Gentry , Michal Mankowski , T. S. Michael , Dorry Segev

Hemodialysis patients who are on donor lists for kidney transplant may get misidentified, delaying their wait time. Thus, predicting their survival time is crucial for optimizing waiting lists and personalizing treatment plans. Predicting…

Machine Learning · Computer Science 2024-12-17 Abhiram Raju , Praneeth Vepakomma

Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making…

Artificial Intelligence · Computer Science 2023-02-21 Sirui Ding , Ruixiang Tang , Daochen Zha , Na Zou , Kai Zhang , Xiaoqian Jiang , Xia Hu

Liver allograft failure occurs in approximately 20% of liver transplant recipients within five years post-transplant, leading to mortality or the need for retransplantation. Providing an accurate and interpretable model for individualized…

Machine Learning · Computer Science 2024-08-13 Xiang Gao , Michael Cooper , Maryam Naghibzadeh , Amirhossein Azhie , Mamatha Bhat , Rahul G. Krishnan

An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival…

Machine Learning · Computer Science 2017-05-30 Margaux Luck , Tristan Sylvain , Héloïse Cardinal , Andrea Lodi , Yoshua Bengio

Kidney paired donation programs (KPDPs) match patients with willing but incompatible donors to compatible donors with an assurance that when they donate, their intended recipient receives a kidney in return from a different donor. A patient…

Optimization and Control · Mathematics 2023-02-13 Lizeth Carolina Riascos-Alvarez , Merve Bodur , Dionne M. Aleman

Motivated by kidney exchange, we study a stochastic cycle and chain packing problem, where we aim to identify structures in a directed graph to maximize the expectation of matched edge weights. All edges are subject to failure, and the…

Artificial Intelligence · Computer Science 2020-07-08 Hoda Bidkhori , John P Dickerson , Duncan C McElfresh , Ke Ren

We consider a well-studied online random graph model for kidney exchange, where nodes representing patient-donor pairs arrive over time, and the probability of a directed edge is p. We assume existence of a single altruistic donor, who…

Computer Science and Game Theory · Computer Science 2020-10-06 Avrim Blum , Yishay Mansour

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be…

Other Quantitative Biology · Quantitative Biology 2023-06-02 Raja Al-Bahou , Julia Bruner , Helen Moore , Ali Zarrinpar
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