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Related papers: Automatic differentiation is no panacea for phylog…

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Gradient-based multilevel optimization (MLO) has gained attention as a framework for studying numerous problems, ranging from hyperparameter optimization and meta-learning to neural architecture search and reinforcement learning. However,…

Machine Learning · Computer Science 2023-03-16 Sang Keun Choe , Willie Neiswanger , Pengtao Xie , Eric Xing

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

While normalizing flows for continuous data have been extensively researched, flows for discrete data have only recently been explored. These prior models, however, suffer from limitations that are distinct from those of continuous flows.…

Machine Learning · Computer Science 2022-07-06 Mai Elkady , Jim Lim , David I. Inouye

Automatic differentiation, as implemented today, does not have a simple mathematical model adapted to the needs of modern machine learning. In this work we articulate the relationships between differentiation of programs as implemented in…

Machine Learning · Computer Science 2020-10-30 Jerome Bolte , Edouard Pauwels

Per-example gradient clipping is a key algorithmic step that enables practical differential private (DP) training for deep learning models. The choice of clipping threshold R, however, is vital for achieving high accuracy under DP. We…

Machine Learning · Computer Science 2023-10-05 Zhiqi Bu , Yu-Xiang Wang , Sheng Zha , George Karypis

As an adaptive, interpretable, robust, and accurate meta-algorithm for arbitrary differentiable loss functions, gradient tree boosting is one of the most popular machine learning techniques, though the computational expensiveness severely…

Machine Learning · Computer Science 2019-11-21 Daniel Chao Zhou , Zhongming Jin , Tong Zhang

Gradient-based bilevel optimisation is a powerful technique with applications in hyperparameter optimisation, task adaptation, algorithm discovery, meta-learning more broadly, and beyond. It often requires differentiating through the…

Machine Learning · Computer Science 2025-06-11 Iurii Kemaev , Dan A Calian , Luisa M Zintgraf , Gregory Farquhar , Hado van Hasselt

Many engineering problems involve learning hidden dynamics from indirect observations, where the physical processes are described by systems of partial differential equations (PDE). Gradient-based optimization methods are considered…

Numerical Analysis · Mathematics 2019-12-17 Kailai Xu , Dongzhuo Li , Eric Darve , Jerry M. Harris

Phylogenetic trees describe the relationships between species in the evolutionary process, and provide information about the rates of diversification. To understand the mechanisms behind macroevolution, we consider a class of multitype…

Populations and Evolution · Quantitative Biology 2024-10-07 Mingqi He , Sophie Hautphenne , Yao-ban Chan

Many biological studies involve inferring the evolutionary history of a sample of individuals from a large population and interpreting the reconstructed tree. Such an ascertained tree typically represents only a small part of a…

Populations and Evolution · Quantitative Biology 2024-08-13 Michael Celentano , William S. DeWitt , Sebastian Prillo , Yun S. Song

Large Language Models (LLMs) have demonstrated remarkable abilities in general scenarios. Instruction finetuning empowers them to align with humans in various tasks. Nevertheless, the Diversity and Quality of the instruction data remain two…

Computation and Language · Computer Science 2024-07-09 Xingyuan Pan , Luyang Huang , Liyan Kang , Zhicheng Liu , Yu Lu , Shanbo Cheng

In this paper, we examine how large language models (LLMs) solve multi-step problems under a language agent framework with three components: a generator, a discriminator, and a planning method. We investigate the practical utility of two…

Computation and Language · Computer Science 2024-06-07 Ziru Chen , Michael White , Raymond Mooney , Ali Payani , Yu Su , Huan Sun

PennyLane is a Python 3 software framework for differentiable programming of quantum computers. The library provides a unified architecture for near-term quantum computing devices, supporting both qubit and continuous-variable paradigms.…

Classification of gene trees is an important task both in the analysis of multi-locus phylogenetic data, and assessment of the convergence of Markov Chain Monte Carlo (MCMC) analyses used in Bayesian phylogenetic tree reconstruction. The…

Combinatorics · Mathematics 2024-06-10 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

We propose a novel method for the inference of phylogenetic trees that utilises point configurations on hyperbolic space as its optimisation landscape. Each taxon corresponds to a point of the point configuration, while the evolutionary…

Machine Learning · Computer Science 2021-06-07 Benjamin Wilson

We present an algorithm for classification tasks on big data. Experiments conducted as part of this study indicate that the algorithm can be as accurate as ensemble methods such as random forests or gradient boosted trees. Unlike ensemble…

Machine Learning · Statistics 2017-10-27 Rajiv Sambasivan , Sourish Das

The Persistent-Phylogeny Model is an extension of the widely studied Perfect-Phylogeny Model, encompassing a broader range of evolutionary phenomena. Biological and algorithmic questions concerning persistent phylogeny have been intensely…

Populations and Evolution · Quantitative Biology 2015-06-03 Dan Gusfield

Application of phylogenetic methods to textual traditions has traditionally treated all changes as equivalent even though it is widely recognized that certain types of variants were more likely to be introduced than others. While it is…

Digital Libraries · Computer Science 2025-11-19 Robert Turnbull

Decision trees and random forest remain highly competitive for classification on medium-sized, standard datasets due to their robustness, minimal preprocessing requirements, and interpretability. However, a single tree suffers from high…

Machine Learning · Statistics 2025-12-02 Cencheng Shen , Yuexiao Dong , Carey E. Priebe

In many evolutionary computation systems, parent selection methods can affect, among other things, convergence to a solution. In this paper, we present a study comparing the role of two commonly used parent selection methods in evolving…